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Items: 1 to 20 of 64

1.

P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis.

Nishida M, Sato Y, Uemura A, Narita Y, Tozaki-Saitoh H, Nakaya M, Ide T, Suzuki K, Inoue K, Nagao T, Kurose H.

EMBO J. 2008 Dec 3;27(23):3104-15. doi: 10.1038/emboj.2008.237. Epub 2008 Nov 13.

2.

G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure.

Takefuji M, Wirth A, Lukasova M, Takefuji S, Boettger T, Braun T, Althoff T, Offermanns S, Wettschureck N.

Circulation. 2012 Oct 16;126(16):1972-82. doi: 10.1161/CIRCULATIONAHA.112.109256. Epub 2012 Sep 12.

3.

UDP induces intestinal epithelial migration via the P2Y6 receptor.

Nakamura T, Murata T, Hori M, Ozaki H.

Br J Pharmacol. 2013 Oct;170(4):883-92. doi: 10.1111/bph.12334.

4.

Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction.

Zhong J, Basu R, Guo D, Chow FL, Byrns S, Schuster M, Loibner H, Wang XH, Penninger JM, Kassiri Z, Oudit GY.

Circulation. 2010 Aug 17;122(7):717-28, 18 p following 728. doi: 10.1161/CIRCULATIONAHA.110.955369. Epub 2010 Aug 2.

5.

Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes In vitro.

Malhotra R, Sadoshima J, Brosius FC 3rd, Izumo S.

Circ Res. 1999 Jul 23;85(2):137-46.

6.

Androgen receptor gene knockout male mice exhibit impaired cardiac growth and exacerbation of angiotensin II-induced cardiac fibrosis.

Ikeda Y, Aihara K, Sato T, Akaike M, Yoshizumi M, Suzaki Y, Izawa Y, Fujimura M, Hashizume S, Kato M, Yagi S, Tamaki T, Kawano H, Matsumoto T, Azuma H, Kato S, Matsumoto T.

J Biol Chem. 2005 Aug 19;280(33):29661-6. Epub 2005 Jun 16.

7.

The opposing effects of CCN2 and CCN5 on the development of cardiac hypertrophy and fibrosis.

Yoon PO, Lee MA, Cha H, Jeong MH, Kim J, Jang SP, Choi BY, Jeong D, Yang DK, Hajjar RJ, Park WJ.

J Mol Cell Cardiol. 2010 Aug;49(2):294-303. doi: 10.1016/j.yjmcc.2010.04.010. Epub 2010 Apr 27.

PMID:
20430035
8.

RhoGEF12 controls cardiac remodeling by integrating G protein- and integrin-dependent signaling cascades.

Takefuji M, Krüger M, Sivaraj KK, Kaibuchi K, Offermanns S, Wettschureck N.

J Exp Med. 2013 Apr 8;210(4):665-73. doi: 10.1084/jem.20122126. Epub 2013 Mar 25.

9.

Protective effects of endogenous adrenomedullin on cardiac hypertrophy, fibrosis, and renal damage.

Niu P, Shindo T, Iwata H, Iimuro S, Takeda N, Zhang Y, Ebihara A, Suematsu Y, Kangawa K, Hirata Y, Nagai R.

Circulation. 2004 Apr 13;109(14):1789-94. Epub 2004 Feb 16.

10.

The renin-angiotensin system and experimental heart failure.

Wollert KC, Drexler H.

Cardiovasc Res. 1999 Sep;43(4):838-49. Review.

PMID:
10615411
11.

Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts.

Li L, Fan D, Wang C, Wang JY, Cui XB, Wu D, Zhou Y, Wu LL.

Cardiovasc Res. 2011 Jul 1;91(1):80-9. doi: 10.1093/cvr/cvr067. Epub 2011 Mar 2.

PMID:
21367774
12.
13.

Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation.

Adam O, Lavall D, Theobald K, Hohl M, Grube M, Ameling S, Sussman MA, Rosenkranz S, Kroemer HK, Schäfers HJ, Böhm M, Laufs U.

J Am Coll Cardiol. 2010 Feb 2;55(5):469-80. doi: 10.1016/j.jacc.2009.08.064.

14.

Tissue Angiotensin-converting enzyme activity plays an important role in pressure overload-induced cardiac fibrosis in rats.

Kurosawa Y, Katoh M, Doi H, Narita H.

J Cardiovasc Pharmacol. 2002 Apr;39(4):600-9.

PMID:
11904534
15.

Regulation of extracellular UTP-activated Cl- current by P2Y-PLC-PKC signaling and ATP hydrolysis in mouse ventricular myocytes.

Yamamoto S, Ichishima K, Ehara T.

J Physiol Sci. 2007 Apr;57(2):85-94. Epub 2007 Feb 11.

PMID:
17291397
16.
17.

G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes.

Nishida M, Tanabe S, Maruyama Y, Mangmool S, Urayama K, Nagamatsu Y, Takagahara S, Turner JH, Kozasa T, Kobayashi H, Sato Y, Kawanishi T, Inoue R, Nagao T, Kurose H.

J Biol Chem. 2005 May 6;280(18):18434-41. Epub 2005 Mar 1.

18.

Connective tissue growth factor and cardiac fibrosis after myocardial infarction.

Dean RG, Balding LC, Candido R, Burns WC, Cao Z, Twigg SM, Burrell LM.

J Histochem Cytochem. 2005 Oct;53(10):1245-56. Epub 2005 Jun 13.

PMID:
15956033
19.

Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy.

Maruyama Y, Nishida M, Sugimoto Y, Tanabe S, Turner JH, Kozasa T, Wada T, Nagao T, Kurose H.

Circ Res. 2002 Nov 15;91(10):961-9.

20.

Cardioprotective effects of granulocyte colony-stimulating factor in angiotensin II-induced cardiac remodelling.

Jia N, Dong P, Huang Q, Jin W, Zhang J, Dai Q, Liu S.

Clin Exp Pharmacol Physiol. 2009 Mar;36(3):262-6. doi: 10.1111/j.1440-1681.2008.05052.x. Epub 2008 Sep 10.

PMID:
18785976

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