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Items: 1 to 20 of 94

1.

Product inhibition of secreted phospholipase A2 may explain lysophosphatidylcholines' unexpected therapeutic properties.

Cunningham TJ, Yao L, Lucena A.

J Inflamm (Lond). 2008 Oct 22;5:17. doi: 10.1186/1476-9255-5-17.

2.

Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9.

Cunningham TJ, Maciejewski J, Yao L.

J Neuroinflammation. 2006 Sep 11;3:25.

3.

Evidence supporting a key role of Lp-PLA2-generated lysophosphatidylcholine in human atherosclerotic plaque inflammation.

Gonçalves I, Edsfeldt A, Ko NY, Grufman H, Berg K, Björkbacka H, Nitulescu M, Persson A, Nilsson M, Prehn C, Adamski J, Nilsson J.

Arterioscler Thromb Vasc Biol. 2012 Jun;32(6):1505-12. doi: 10.1161/ATVBAHA.112.249854. Epub 2012 Apr 12.

4.

An essential role for lysophosphatidylcholine in the inhibition of platelet aggregation by secretory phospholipase A2.

Yuan Y, Jackson SP, Newnham HH, Mitchell CA, Salem HH.

Blood. 1995 Dec 1;86(11):4166-74.

5.

Accumulation of bioactive lipids during storage of blood products is not cell but plasma derived and temperature dependent.

Vlaar AP, Kulik W, Nieuwland R, Peters CP, Tool AT, van Bruggen R, Juffermans NP, de Korte D.

Transfusion. 2011 Nov;51(11):2358-66. doi: 10.1111/j.1537-2995.2011.03177.x. Epub 2011 May 16.

PMID:
21575006
6.

Treatment with beta-blockers is associated with lower levels of Lp-PLA2 and suPAR in carotid plaques.

Asciutto G, Edsfeldt A, Dias NV, Nilsson J, Prehn C, Adamski J, Gonçalves I.

Cardiovasc Pathol. 2013 Nov-Dec;22(6):438-43. doi: 10.1016/j.carpath.2013.04.005. Epub 2013 Jun 6.

PMID:
23747086
7.

Lysophosphatidylcholine enhances susceptibility in signaling pathway against pathogen infection through biphasic production of reactive oxygen species and ethylene in tobacco plants.

Wi SJ, Seo Sy, Cho K, Nam MH, Park KY.

Phytochemistry. 2014 Aug;104:48-59. doi: 10.1016/j.phytochem.2014.04.009. Epub 2014 May 13.

PMID:
24837357
8.
9.
10.

Lysophosphatidylcholine and carotid intima-media thickness in young smokers: a role for oxidized LDL-induced expression of PBMC lipoprotein-associated phospholipase A2?

Fratta Pasini A, Stranieri C, Pasini A, Vallerio P, Mozzini C, Solani E, Cominacini M, Cominacini L, Garbin U.

PLoS One. 2013 Dec 17;8(12):e83092. doi: 10.1371/journal.pone.0083092. eCollection 2013.

11.

Secreted phospholipase A2 involvement in neurodegeneration: differential testing of prosurvival and anti-inflammatory effects of enzyme inhibition.

Chen S, Yao L, Cunningham TJ.

PLoS One. 2012;7(6):e39257. doi: 10.1371/journal.pone.0039257. Epub 2012 Jun 15.

12.

Oral administration of 2-docosahexaenoyl lysophosphatidylcholine displayed anti-inflammatory effects on zymosan A-induced peritonitis.

Hung ND, Kim MR, Sok DE.

Inflammation. 2011 Jun;34(3):147-60. doi: 10.1007/s10753-010-9218-z.

PMID:
20490641
13.
14.

Anti-inflammatory action of arachidonoyl lysophosphatidylcholine or 15-hydroperoxy derivative in zymosan A-induced peritonitis.

Hung ND, Kim MR, Sok DE.

Prostaglandins Other Lipid Mediat. 2009 Dec;90(3-4):105-11. doi: 10.1016/j.prostaglandins.2009.10.001. Epub 2009 Oct 9.

PMID:
19819343
15.

Secreted phospholipase A2 activity in experimental autoimmune encephalomyelitis and multiple sclerosis.

Cunningham TJ, Yao L, Oetinger M, Cort L, Blankenhorn EP, Greenstein JI.

J Neuroinflammation. 2006 Sep 11;3:26.

16.

Secretory PLA2 inhibitor indoxam suppresses LDL modification and associated inflammatory responses in TNFalpha-stimulated human endothelial cells.

Sonoki K, Iwase M, Sasaki N, Ohdo S, Higuchi S, Takata Y, Iida M.

Br J Pharmacol. 2008 Apr;153(7):1399-408. doi: 10.1038/bjp.2008.12. Epub 2008 Feb 11.

17.

Potentiation of tumor necrosis factor alpha-induced secreted phospholipase A2 (sPLA2)-IIA expression in mesangial cells by an autocrine loop involving sPLA2 and peroxisome proliferator-activated receptor alpha activation.

Beck S, Lambeau G, Scholz-Pedretti K, Gelb MH, Janssen MJ, Edwards SH, Wilton DC, Pfeilschifter J, Kaszkin M.

J Biol Chem. 2003 Aug 8;278(32):29799-812. Epub 2003 Jun 2.

18.

Regulation of lipoxygenase activity by polyunsaturated lysophosphatidylcholines or their oxygenation derivatives.

Huang LS, Kim MR, Sok DE.

J Agric Food Chem. 2008 Sep 10;56(17):7808-14. doi: 10.1021/jf801082x. Epub 2008 Aug 5.

PMID:
18680379
19.

Suppression of murine endotoxic shock by sPLA2 inhibitor, indoxam, through group IIA sPLA2-independent mechanisms.

Yokota Y, Hanasaki K, Ono T, Nakazato H, Kobayashi T, Arita H.

Biochim Biophys Acta. 1999 May 18;1438(2):213-22.

PMID:
10320804
20.

Glucocorticoids suppress basal (but not interleukin-1-supported) ovarian phospholipase A2 activity: evidence for glucocorticoid receptor-mediated regulation.

Kol S, Ben-Shlomo I, Payne DW, Ando M, Rohan RM, Adashi EY.

Mol Cell Endocrinol. 1998 Feb;137(2):117-25.

PMID:
9605513

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