Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 178


The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpoint.

Osmundson EC, Ray D, Moore FE, Gao Q, Thomsen GH, Kiyokawa H.

J Cell Biol. 2008 Oct 20;183(2):267-77. doi: 10.1083/jcb.200801049. Epub 2008 Oct 13.


Smurf2 as a novel mitotic regulator: From the spindle assembly checkpoint to tumorigenesis.

Osmundson EC, Ray D, Moore FE, Kiyokawa H.

Cell Div. 2009 Jul 7;4:14. doi: 10.1186/1747-1028-4-14.


Requirement for proteolysis in spindle assembly checkpoint silencing.

Visconti R, Palazzo L, Grieco D.

Cell Cycle. 2010 Feb 1;9(3):564-9.


Orderly inactivation of the key checkpoint protein mitotic arrest deficient 2 (MAD2) during mitotic progression.

Ma HT, Poon RY.

J Biol Chem. 2011 Apr 15;286(15):13052-9. doi: 10.1074/jbc.M110.201897. Epub 2011 Feb 18.


BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional mitotic checkpoint complex.

Tipton AR, Wang K, Link L, Bellizzi JJ, Huang H, Yen T, Liu ST.

J Biol Chem. 2011 Jun 17;286(24):21173-9. doi: 10.1074/jbc.M111.238543. Epub 2011 Apr 27.


Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding.

Kulukian A, Han JS, Cleveland DW.

Dev Cell. 2009 Jan;16(1):105-17. doi: 10.1016/j.devcel.2008.11.005.


APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation.

Ge S, Skaar JR, Pagano M.

Cell Cycle. 2009 Jan 1;8(1):167-71. Epub 2009 Jan 11.


Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint.

Xia G, Luo X, Habu T, Rizo J, Matsumoto T, Yu H.

EMBO J. 2004 Aug 4;23(15):3133-43. Epub 2004 Jul 15.


The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.

Nilsson J, Yekezare M, Minshull J, Pines J.

Nat Cell Biol. 2008 Dec;10(12):1411-20. doi: 10.1038/ncb1799. Epub 2008 Nov 9.


The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).

Sczaniecka M, Feoktistova A, May KM, Chen JS, Blyth J, Gould KL, Hardwick KG.

J Biol Chem. 2008 Aug 22;283(34):23039-47. doi: 10.1074/jbc.M803594200. Epub 2008 Jun 13.


Defining pathways of spindle checkpoint silencing: functional redundancy between Cdc20 ubiquitination and p31(comet).

Jia L, Li B, Warrington RT, Hao X, Wang S, Yu H.

Mol Biol Cell. 2011 Nov;22(22):4227-35. doi: 10.1091/mbc.E11-05-0389. Epub 2011 Sep 21.


Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation.

Izawa D, Pines J.

J Cell Biol. 2012 Oct 1;199(1):27-37. doi: 10.1083/jcb.201205170. Epub 2012 Sep 24.


The spindle checkpoint requires cyclin-dependent kinase activity.

D'Angiolella V, Mari C, Nocera D, Rametti L, Grieco D.

Genes Dev. 2003 Oct 15;17(20):2520-5.


APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.

Mansfeld J, Collin P, Collins MO, Choudhary JS, Pines J.

Nat Cell Biol. 2011 Sep 18;13(10):1234-43. doi: 10.1038/ncb2347.


Regulation of APC-Cdc20 by the spindle checkpoint.

Yu H.

Curr Opin Cell Biol. 2002 Dec;14(6):706-14. Review.


Supplemental Content

Support Center