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Items: 1 to 20 of 96

1.

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin.

Boerma M, Fu Q, Wang J, Loose DS, Bartolozzi A, Ellis JL, McGonigle S, Paradise E, Sweetnam P, Fink LM, Vozenin-Brotons MC, Hauer-Jensen M.

Blood Coagul Fibrinolysis. 2008 Oct;19(7):709-18. doi: 10.1097/MBC.0b013e32830b2891.

2.

Comparative expression profiling in primary and immortalized endothelial cells: changes in gene expression in response to hydroxy methylglutaryl-coenzyme A reductase inhibition.

Boerma M, Burton GR, Wang J, Fink LM, McGehee RE Jr, Hauer-Jensen M.

Blood Coagul Fibrinolysis. 2006 Apr;17(3):173-80.

PMID:
16575254
3.

Atorvastatin inhibits myocardin expression in vascular smooth muscle cells.

Li J, Jiang J, Yin H, Wang L, Tian R, Li H, Wang Z, Li D, Wang Y, Gui Y, Walsh MP, Zheng XL.

Hypertension. 2012 Jul;60(1):145-53. doi: 10.1161/HYPERTENSIONAHA.112.195644. Epub 2012 May 21.

4.

Atorvastatin inhibited Rho-associated kinase 1 (ROCK1) and focal adhesion kinase (FAK) mediated adhesion and differentiation of CD133+CD44+ prostate cancer stem cells.

Rentala S, Chintala R, Guda M, Chintala M, Komarraju AL, Mangamoori LN.

Biochem Biophys Res Commun. 2013 Nov 22;441(3):586-92. doi: 10.1016/j.bbrc.2013.10.112. Epub 2013 Oct 29.

PMID:
24177008
5.

Discovery of Rho-kinase inhibitors by docking-based virtual screening.

Shen M, Yu H, Li Y, Li P, Pan P, Zhou S, Zhang L, Li S, Lee SM, Hou T.

Mol Biosyst. 2013 Jun;9(6):1511-21. doi: 10.1039/c3mb00016h. Epub 2013 Apr 3.

PMID:
23549429
6.

Atorvastatin ameliorates sildenafil-induced penile erections in experimental diabetes by inhibiting diabetes-induced RhoA/Rho-kinase signaling hyperactivation.

Morelli A, Chavalmane AK, Filippi S, Fibbi B, Silvestrini E, Sarchielli E, Zhang XH, Vignozzi L, Vannelli GB, Forti G, Maggi M.

J Sex Med. 2009 Jan;6(1):91-106. doi: 10.1111/j.1743-6109.2008.01057.x.

PMID:
19170840
7.

The molecular mechanism of the anticancer effect of atorvastatin: DNA microarray and bioinformatic analyses.

Gao Y, Lu XC, Yang HY, Liu XF, Cao J, Fan L.

Int J Mol Med. 2012 Oct;30(4):765-74. doi: 10.3892/ijmm.2012.1054. Epub 2012 Jul 4.

PMID:
22766564
8.

Atorvastatin but not elocalcitol increases sildenafil responsiveness in spontaneously hypertensive rats by regulating the RhoA/ROCK pathway.

Fibbi B, Morelli A, Marini M, Zhang XH, Mancina R, Vignozzi L, Filippi S, Chavalmane A, Silvestrini E, Colli E, Adorini L, Vannelli GB, Maggi M.

J Androl. 2008 Jan-Feb;29(1):70-84. Epub 2007 Aug 15.

9.

Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors.

Rodríguez C, Alcudia JF, Martínez-González J, Guadall A, Raposo B, Sánchez-Gómez S, Badimon L.

Cardiovasc Res. 2009 Aug 1;83(3):595-603. doi: 10.1093/cvr/cvp136. Epub 2009 Apr 30.

PMID:
19406911
10.

Development of Rho-kinase inhibitors for cardiovascular medicine.

Shimokawa H, Rashid M.

Trends Pharmacol Sci. 2007 Jun;28(6):296-302. Epub 2007 May 7. Review.

PMID:
17482681
11.

Atorvastatin treatment improves the effects of mesenchymal stem cell transplantation on acute myocardial infarction: the role of the RhoA/ROCK/ERK pathway.

Zhang Q, Wang H, Yang YJ, Dong QT, Wang TJ, Qian HY, Li N, Wang XM, Jin C.

Int J Cardiol. 2014 Oct 20;176(3):670-9. doi: 10.1016/j.ijcard.2014.07.071. Epub 2014 Aug 1.

PMID:
25139321
12.

Angiogenic transcriptome of human microvascular endothelial cells: Effect of hypoxia, modulation by atorvastatin.

Loboda A, Jazwa A, Jozkowicz A, Molema G, Dulak J.

Vascul Pharmacol. 2006 Apr;44(4):206-14. Epub 2006 Feb 14.

13.

Mechanism of the inhibitory effect of atorvastatin on endoglin expression induced by transforming growth factor-beta1 in cultured cardiac fibroblasts.

Shyu KG, Wang BW, Chen WJ, Kuan P, Hung CR.

Eur J Heart Fail. 2010 Mar;12(3):219-26. doi: 10.1093/eurjhf/hfq011.

14.

Atorvastatin prevents angiotensin II-induced high permeability of human arterial endothelial cell monolayers via ROCK signaling pathway.

Yi R, Xiao-Ping G, Hui L.

Biochem Biophys Res Commun. 2015 Mar 27;459(1):94-9. doi: 10.1016/j.bbrc.2015.02.076. Epub 2015 Feb 21.

PMID:
25712521
15.

[Roles of periostin in proliferation and migration of vascular smooth muscle cells and the effect of atorvastatin on them].

Li J, Yan W, Wang J, Tan W, Zhou Y, Yang K.

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012 Jul;37(7):689-94. doi: 10.3969/j.issn.1672-7347.2012.07.007. Chinese.

16.

The mechanism underlying vascular smooth muscle cell apoptosis induced by atorvastatin may be mainly associated with down-regulation of survivin expression.

Xu YG, Zhou SH, Li YG, Zheng CH, Li XP, Liu QM, Xu DM, Chen S.

Cardiovasc Drugs Ther. 2007 Jun;21(3):145-53.

PMID:
17372815
17.

Inhibition of serotonin-induced mitogenesis, migration, and ERK MAPK nuclear translocation in vascular smooth muscle cells by atorvastatin.

Li M, Liu Y, Dutt P, Fanburg BL, Toksoz D.

Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L463-71. Epub 2007 Jun 1.

18.

2-methoxyestradiol inhibits atorvastatin-induced rounding of human vascular smooth muscle cells.

Yin H, Gui Y, Zheng XL.

J Cell Physiol. 2010 Mar;222(3):556-64. doi: 10.1002/jcp.21970.

PMID:
19937728
19.

Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid atherosclerotic plaques: modulation by atorvastatin.

Muñoz-García B, Martín-Ventura JL, Martínez E, Sánchez S, Hernández G, Ortega L, Ortiz A, Egido J, Blanco-Colio LM.

Stroke. 2006 Aug;37(8):2044-53. Epub 2006 Jun 29.

20.

Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitors.

Rashid M, Tawara S, Fukumoto Y, Seto M, Yano K, Shimokawa H.

Circ J. 2009 Feb;73(2):361-70. Epub 2008 Dec 8.

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