Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 111

1.

Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model.

Howard KA, Paludan SR, Behlke MA, Besenbacher F, Deleuran B, Kjems J.

Mol Ther. 2009 Jan;17(1):162-8. doi: 10.1038/mt.2008.220. Epub 2008 Sep 30.

2.

Chitosan/siRNA Nanoparticle-mediated TNF-α Knockdown in Peritoneal Macrophages for Anti-inflammatory Treatment in a Murine Arthritis Model.

Howard KA, Paludan SR, Behlke MA, Besenbacher F, Deleuran B, Kjems J.

Mol Ther. 2009 Jan;17(1):162-168. doi: 10.1038/mt.2008.220. Epub 2016 Dec 6.

3.

Peritoneal macrophages mediated delivery of chitosan/siRNA nanoparticle to the lesion site in a murine radiation-induced fibrosis model.

Nawroth I, Alsner J, Deleuran BW, Dagnaes-Hansen F, Yang C, Horsman MR, Overgaard J, Howard KA, Kjems J, Gao S.

Acta Oncol. 2013 Nov;52(8):1730-8. doi: 10.3109/0284186X.2012.726373. Epub 2012 Oct 1.

PMID:
23020526
4.

MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model.

te Boekhorst BC, Jensen LB, Colombo S, Varkouhi AK, Schiffelers RM, Lammers T, Storm G, Nielsen HM, Strijkers GJ, Foged C, Nicolay K.

J Control Release. 2012 Aug 10;161(3):772-80. doi: 10.1016/j.jconrel.2012.05.004. Epub 2012 May 11.

PMID:
22580113
5.

Trimethyl chitosan-cysteine nanoparticles for systemic delivery of TNF-α siRNA via oral and intraperitoneal routes.

He C, Yin L, Tang C, Yin C.

Pharm Res. 2013 Oct;30(10):2596-606. doi: 10.1007/s11095-013-1086-4. Epub 2013 May 29.

PMID:
23715740
6.

TNF-α gene silencing using polymerized siRNA/thiolated glycol chitosan nanoparticles for rheumatoid arthritis.

Lee SJ, Lee A, Hwang SR, Park JS, Jang J, Huh MS, Jo DG, Yoon SY, Byun Y, Kim SH, Kwon IC, Youn I, Kim K.

Mol Ther. 2014 Feb;22(2):397-408. doi: 10.1038/mt.2013.245. Epub 2013 Oct 22.

7.

Optimization of multifunctional chitosan-siRNA nanoparticles for oral delivery applications, targeting TNF-α silencing in rats.

He C, Yin L, Song Y, Tang C, Yin C.

Acta Biomater. 2015 Apr;17:98-106. doi: 10.1016/j.actbio.2015.01.041. Epub 2015 Feb 7.

PMID:
25662912
8.

Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis.

Joosten LA, Lubberts E, Helsen MM, Saxne T, Coenen-de Roo CJ, Heinegård D, van den Berg WB.

Arthritis Res. 1999;1(1):81-91. Epub 1999 Oct 26.

9.

Multifunctional polymeric nanoparticles for oral delivery of TNF-α siRNA to macrophages.

He C, Yin L, Tang C, Yin C.

Biomaterials. 2013 Apr;34(11):2843-54. doi: 10.1016/j.biomaterials.2013.01.033. Epub 2013 Jan 21.

PMID:
23347838
10.

Silencing TNF-α in macrophages and dendritic cells for arthritis treatment.

Ye C, Bhan AK, Deshpande V, Shankar P, Manjunath N.

Scand J Rheumatol. 2013;42(4):266-9. doi: 10.3109/03009742.2013.777779. Epub 2013 Apr 14.

PMID:
23582054
11.
12.

TNF receptor gene therapy results in suppression of IgG2a anticollagen antibody in collagen induced arthritis.

Mukherjee P, Wu B, Mayton L, Kim SH, Robbins PD, Wooley PH.

Ann Rheum Dis. 2003 Aug;62(8):707-14.

13.

Urocanic acid-modified chitosan nanoparticles can confer anti-inflammatory effect by delivering CD98 siRNA to macrophages.

Xiao B, Ma P, Viennois E, Merlin D.

Colloids Surf B Biointerfaces. 2016 Jul 1;143:186-93. doi: 10.1016/j.colsurfb.2016.03.035. Epub 2016 Mar 14.

PMID:
27011348
14.

Suppression of experimental arthritis with self-assembling glycol-split heparin nanoparticles via inhibition of TLR4-NF-κB signaling.

Babazada H, Yamashita F, Hashida M.

J Control Release. 2014 Nov 28;194:295-300. doi: 10.1016/j.jconrel.2014.09.015. Epub 2014 Sep 19.

PMID:
25242730
15.

Arthritic joint-targeting small interfering RNA-encapsulated liposome: implication for treatment strategy for rheumatoid arthritis.

Komano Y, Yagi N, Onoue I, Kaneko K, Miyasaka N, Nanki T.

J Pharmacol Exp Ther. 2012 Jan;340(1):109-13. doi: 10.1124/jpet.111.185884. Epub 2011 Oct 12.

16.

Effects of mannose density on in vitro and in vivo cellular uptake and RNAi efficiency of polymeric nanoparticles.

Chu S, Tang C, Yin C.

Biomaterials. 2015 Jun;52:229-39. doi: 10.1016/j.biomaterials.2015.02.044. Epub 2015 Feb 27.

PMID:
25818429
18.

Chitosan/siRNA nanoparticles targeting cyclooxygenase type 2 attenuate unilateral ureteral obstruction-induced kidney injury in mice.

Yang C, Nilsson L, Cheema MU, Wang Y, Frøkiær J, Gao S, Kjems J, Nørregaard R.

Theranostics. 2015 Jan 1;5(2):110-23. doi: 10.7150/thno.9717. eCollection 2015.

19.

Anti-CD4 monoclonal antibody treatment in acute and early chronic antigen induced arthritis: influence on macrophage activation.

Nissler K, Pohlers D, Hückel M, Simon J, Bräuer R, Kinne RW.

Ann Rheum Dis. 2004 Nov;63(11):1470-7.

20.

Inflammation-inducible anti-TNF gene expression mediated by intra-articular injection of serotype 5 adeno-associated virus reduces arthritis.

Khoury M, Adriaansen J, Vervoordeldonk MJ, Gould D, Chernajovsky Y, Bigey P, Bloquel C, Scherman D, Tak PP, Jorgensen C, Apparailly F.

J Gene Med. 2007 Jul;9(7):596-604.

PMID:
17514770

Supplemental Content

Support Center