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Items: 1 to 20 of 166

1.

Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination.

Balkhi MY, Fitzgerald KA, Pitha PM.

Mol Cell Biol. 2008 Dec;28(24):7296-308. doi: 10.1128/MCB.00662-08. Epub 2008 Sep 29.

2.

IKKalpha negatively regulates IRF-5 function in a MyD88-TRAF6 pathway.

Balkhi MY, Fitzgerald KA, Pitha PM.

Cell Signal. 2010 Jan;22(1):117-27. doi: 10.1016/j.cellsig.2009.09.021. Epub 2009 Sep 25.

PMID:
19786094
4.

Human parainfluenza virus type 2 V protein inhibits TRAF6-mediated ubiquitination of IRF7 to prevent TLR7- and TLR9-dependent interferon induction.

Kitagawa Y, Yamaguchi M, Zhou M, Nishio M, Itoh M, Gotoh B.

J Virol. 2013 Jul;87(14):7966-76. doi: 10.1128/JVI.03525-12. Epub 2013 May 15.

5.

Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling.

Tanishima M, Takashima S, Honda A, Yasuda D, Tanikawa T, Ishii S, MaruYama T.

J Biol Chem. 2017 Oct 20;292(42):17250-17257. doi: 10.1074/jbc.M117.813899. Epub 2017 Sep 7.

PMID:
28882891
6.

Signaling flux redistribution at toll-like receptor pathway junctions.

Selvarajoo K, Takada Y, Gohda J, Helmy M, Akira S, Tomita M, Tsuchiya M, Inoue J, Matsuo K.

PLoS One. 2008;3(10):e3430. doi: 10.1371/journal.pone.0003430. Epub 2008 Oct 17.

7.

Differential activation of IFN regulatory factor (IRF)-3 and IRF-5 transcription factors during viral infection.

Cheng TF, Brzostek S, Ando O, Van Scoy S, Kumar KP, Reich NC.

J Immunol. 2006 Jun 15;176(12):7462-70.

8.

Identification of IRF-8 and IRF-1 target genes in activated macrophages.

Dror N, Alter-Koltunoff M, Azriel A, Amariglio N, Jacob-Hirsch J, Zeligson S, Morgenstern A, Tamura T, Hauser H, Rechavi G, Ozato K, Levi BZ.

Mol Immunol. 2007 Jan;44(4):338-46. Epub 2006 Apr 4.

PMID:
16597464
9.

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.

Newton K, Matsumoto ML, Wertz IE, Kirkpatrick DS, Lill JR, Tan J, Dugger D, Gordon N, Sidhu SS, Fellouse FA, Komuves L, French DM, Ferrando RE, Lam C, Compaan D, Yu C, Bosanac I, Hymowitz SG, Kelley RF, Dixit VM.

Cell. 2008 Aug 22;134(4):668-78. doi: 10.1016/j.cell.2008.07.039.

10.

TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1.

Ning S, Campos AD, Darnay BG, Bentz GL, Pagano JS.

Mol Cell Biol. 2008 Oct;28(20):6536-46. doi: 10.1128/MCB.00785-08. Epub 2008 Aug 18.

11.

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation.

Conze DB, Wu CJ, Thomas JA, Landstrom A, Ashwell JD.

Mol Cell Biol. 2008 May;28(10):3538-47. doi: 10.1128/MCB.02098-07. Epub 2008 Mar 17.

12.

TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor.

Geetha T, Kenchappa RS, Wooten MW, Carter BD.

EMBO J. 2005 Nov 16;24(22):3859-68. Epub 2005 Oct 27.

13.

Direct binding of TRAF2 and TRAF6 to TICAM-1/TRIF adaptor participates in activation of the Toll-like receptor 3/4 pathway.

Sasai M, Tatematsu M, Oshiumi H, Funami K, Matsumoto M, Hatakeyama S, Seya T.

Mol Immunol. 2010 Mar;47(6):1283-91. doi: 10.1016/j.molimm.2009.12.002. Epub 2010 Jan 4.

PMID:
20047764
14.

TRAF6 promotes ubiquitination and regulated intramembrane proteolysis of IL-1R1.

Twomey C, Qian S, McCarthy JV.

Biochem Biophys Res Commun. 2009 Apr 10;381(3):418-23. doi: 10.1016/j.bbrc.2009.02.051. Epub 2009 Feb 20.

PMID:
19232518
15.

TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia.

Liu A, Gong P, Hyun SW, Wang KZ, Cates EA, Perkins D, Bannerman DD, Puché AC, Toshchakov VY, Fang S, Auron PE, Vogel SN, Goldblum SE.

J Biol Chem. 2012 May 11;287(20):16132-45. doi: 10.1074/jbc.M111.310102. Epub 2012 Mar 23.

16.

IRAK-1-mediated negative regulation of Toll-like receptor signaling through proteasome-dependent downregulation of TRAF6.

Muroi M, Tanamoto K.

Biochim Biophys Acta. 2012 Feb;1823(2):255-63. doi: 10.1016/j.bbamcr.2011.10.003. Epub 2011 Oct 18.

17.

Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc.

Alter-Koltunoff M, Goren S, Nousbeck J, Feng CG, Sher A, Ozato K, Azriel A, Levi BZ.

J Biol Chem. 2008 Feb 1;283(5):2724-33. Epub 2007 Nov 28. Erratum in: J Biol Chem. 2008 Aug 8;283(32):22336.

18.

Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells.

Kwa MQ, Nguyen T, Huynh J, Ramnath D, De Nardo D, Lam PY, Reynolds EC, Hamilton JA, Sweet MJ, Scholz GM.

J Biol Chem. 2014 Jul 11;289(28):19758-68. doi: 10.1074/jbc.M114.584540. Epub 2014 May 28.

19.

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction.

Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi O, Akira S.

J Exp Med. 2005 Mar 21;201(6):915-23. Epub 2005 Mar 14.

20.

UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination.

Zhang X, Zhang J, Zhang L, van Dam H, ten Dijke P.

Cell Res. 2013 Mar;23(3):366-77. doi: 10.1038/cr.2013.21. Epub 2013 Feb 5.

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