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Items: 1 to 20 of 226

1.

Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon.

Omodei D, Acampora D, Mancuso P, Prakash N, Di Giovannantonio LG, Wurst W, Simeone A.

Development. 2008 Oct;135(20):3459-70. doi: 10.1242/dev.027003.

2.

Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells.

Ono Y, Nakatani T, Sakamoto Y, Mizuhara E, Minaki Y, Kumai M, Hamaguchi A, Nishimura M, Inoue Y, Hayashi H, Takahashi J, Imai T.

Development. 2007 Sep;134(17):3213-25. Epub 2007 Aug 1.

3.

Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon.

Nakatani T, Kumai M, Mizuhara E, Minaki Y, Ono Y.

Dev Biol. 2010 Mar 1;339(1):101-13. doi: 10.1016/j.ydbio.2009.12.017. Epub 2009 Dec 24.

4.

Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain.

Di Salvio M, Di Giovannantonio LG, Omodei D, Acampora D, Simeone A.

Int J Dev Biol. 2010;54(5):939-45. doi: 10.1387/ijdb.092974ms.

5.

Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis.

Jönsson ME, Ono Y, Björklund A, Thompson LH.

Exp Neurol. 2009 Sep;219(1):341-54. doi: 10.1016/j.expneurol.2009.06.006. Epub 2009 Jun 23.

PMID:
19555687
6.

Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3.

Roybon L, Hjalt T, Christophersen NS, Li JY, Brundin P.

J Neurosci. 2008 Apr 2;28(14):3644-56. doi: 10.1523/JNEUROSCI.0311-08.2008.

7.

Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability.

Di Giovannantonio LG, Di Salvio M, Acampora D, Prakash N, Wurst W, Simeone A.

Dev Biol. 2013 Jan 1;373(1):176-83. doi: 10.1016/j.ydbio.2012.10.022. Epub 2012 Oct 29.

8.

Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells.

Andersson EK, Irvin DK, Ahlsiö J, Parmar M.

Exp Cell Res. 2007 Apr 1;313(6):1172-80. Epub 2006 Dec 30.

PMID:
17291494
9.

Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.

Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A.

Development. 2014 Jan;141(2):377-88. doi: 10.1242/dev.102954. Epub 2013 Dec 11.

10.

Otx genes in neurogenesis of mesencephalic dopaminergic neurons.

Simeone A, Puelles E, Omodei D, Acampora D, Di Giovannantonio LG, Di Salvio M, Mancuso P, Tomasetti C.

Dev Neurobiol. 2011 Aug;71(8):665-79. doi: 10.1002/dneu.20877. Review.

11.

The role of Otx genes in progenitor domains of ventral midbrain.

Simeone A, Puelles E, Acampora D, Omodei D, Mancuso P, Giovanni Di Giovannantonio L.

Adv Exp Med Biol. 2009;651:36-46. Review.

PMID:
19731548
12.

Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon.

Thompson LH, Andersson E, Jensen JB, Barraud P, Guillemot F, Parmar M, Björklund A.

Exp Neurol. 2006 Mar;198(1):183-98. Epub 2006 Jan 24.

PMID:
16438966
13.

Otx2 regulates subtype specification and neurogenesis in the midbrain.

Vernay B, Koch M, Vaccarino F, Briscoe J, Simeone A, Kageyama R, Ang SL.

J Neurosci. 2005 May 11;25(19):4856-67.

14.

Organization of the human embryonic ventral mesencephalon.

Nelander J, Hebsgaard JB, Parmar M.

Gene Expr Patterns. 2009 Dec;9(8):555-61. doi: 10.1016/j.gep.2009.10.002. Epub 2009 Oct 13.

PMID:
19825428
15.

Murine embryonic EGF-responsive ventral mesencephalic neurospheres display distinct regional specification and promote survival of dopaminergic neurons.

Moses D, Teper Y, Gantois I, Finkelstein DI, Horne MK, Drago J.

Exp Neurol. 2006 May;199(1):209-21. Epub 2006 Apr 19.

PMID:
16626706
16.

Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: effects on locomotor behavior and seizure susceptibility.

Tripathi PP, Di Giovannantonio LG, Sanguinetti E, Acampora D, Allegra M, Caleo M, Wurst W, Simeone A, Bozzi Y.

Neuroscience. 2014 Mar 7;261:173-83. doi: 10.1016/j.neuroscience.2013.12.045. Epub 2013 Dec 30.

PMID:
24384227
17.

Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons.

Smits SM, Ponnio T, Conneely OM, Burbach JP, Smidt MP.

Eur J Neurosci. 2003 Oct;18(7):1731-8.

PMID:
14622207
18.

Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons.

Rössler R, Boddeke E, Copray S.

Neuroscience. 2010 Oct 13;170(2):417-28. doi: 10.1016/j.neuroscience.2010.07.023. Epub 2010 Jul 17.

PMID:
20643196
19.

Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain.

Puelles E, Annino A, Tuorto F, Usiello A, Acampora D, Czerny T, Brodski C, Ang SL, Wurst W, Simeone A.

Development. 2004 May;131(9):2037-48.

20.

Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2.

Andersson E, Jensen JB, Parmar M, Guillemot F, Björklund A.

Development. 2006 Feb;133(3):507-16. Epub 2006 Jan 5.

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