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Items: 1 to 20 of 129

1.

MLL5 contributes to hematopoietic stem cell fitness and homeostasis.

Zhang Y, Wong J, Klinger M, Tran MT, Shannon KM, Killeen N.

Blood. 2009 Feb 12;113(7):1455-63. doi: 10.1182/blood-2008-05-159905.

2.

Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation.

Heuser M, Yap DB, Leung M, de Algara TR, Tafech A, McKinney S, Dixon J, Thresher R, Colledge B, Carlton M, Humphries RK, Aparicio SA.

Blood. 2009 Feb 12;113(7):1432-43. doi: 10.1182/blood-2008-06-162263.

3.

Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5.

Madan V, Madan B, Brykczynska U, Zilbermann F, Hogeveen K, Döhner K, Döhner H, Weber O, Blum C, Rodewald HR, Sassone-Corsi P, Peters AH, Fehling HJ.

Blood. 2009 Feb 12;113(7):1444-54. doi: 10.1182/blood-2008-02-142638.

4.

Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.

Jones M, Chase J, Brinkmeier M, Xu J, Weinberg DN, Schira J, Friedman A, Malek S, Grembecka J, Cierpicki T, Dou Y, Camper SA, Maillard I.

J Clin Invest. 2015 May;125(5):2007-20. doi: 10.1172/JCI78124.

5.

Thymus reconstitution by c-kit-expressing hematopoietic stem cells purified from adult mouse bone marrow.

de Vries P, Brasel KA, McKenna HJ, Williams DE, Watson JD.

J Exp Med. 1992 Dec 1;176(6):1503-9.

7.

Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia.

Thorsteinsdottir U, Sauvageau G, Hough MR, Dragowska W, Lansdorp PM, Lawrence HJ, Largman C, Humphries RK.

Mol Cell Biol. 1997 Jan;17(1):495-505.

8.

STAT5 promotes multilineage hematolymphoid development in vivo through effects on early hematopoietic progenitor cells.

Snow JW, Abraham N, Ma MC, Abbey NW, Herndier B, Goldsmith MA.

Blood. 2002 Jan 1;99(1):95-101.

9.

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation.

Wilson A, Murphy MJ, Oskarsson T, Kaloulis K, Bettess MD, Oser GM, Pasche AC, Knabenhans C, Macdonald HR, Trumpp A.

Genes Dev. 2004 Nov 15;18(22):2747-63.

10.

Disruption of bis leads to the deterioration of the vascular niche for hematopoietic stem cells.

Kwon KR, Ahn JY, Kim MS, Jung JY, Lee JH, Oh IH.

Stem Cells. 2010 Feb;28(2):268-78. doi: 10.1002/stem.285.

11.

In vitro and in vivo effects of a farnesyltransferase inhibitor on Nf1-deficient hematopoietic cells.

Mahgoub N, Taylor BR, Gratiot M, Kohl NE, Gibbs JB, Jacks T, Shannon KM.

Blood. 1999 Oct 1;94(7):2469-76.

12.

Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells.

Eto T, Winkler I, Purton LE, Lévesque JP.

Exp Hematol. 2005 Feb;33(2):232-42.

PMID:
15676218
13.

Retroviral transduction of enriched hematopoietic stem cells allows lifelong Bcl-2 expression in multiple lineages but does not perturb hematopoiesis.

Innes KM, Szilvassy SJ, Davidson HE, Gibson L, Adams JM, Cory S.

Exp Hematol. 1999 Jan;27(1):75-87.

PMID:
9923446
14.

The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression.

Orelio C, Harvey KN, Miles C, Oostendorp RA, van der Horn K, Dzierzak E.

Blood. 2004 Jun 1;103(11):4084-92.

15.

Thrombopoietic potential and serial repopulating ability of murine hematopoietic stem cells constitutively expressing interleukin 11.

Hawley RG, Hawley TS, Fong AZ, Quinto C, Collins M, Leonard JP, Goldman SJ.

Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10297-302.

16.

Bone marrow connexin-43 expression is critical for hematopoietic regeneration after chemotherapy.

Presley CA, Lee AW, Kastl B, Igbinosa I, Yamada Y, Fishman GI, Gutstein DE, Cancelas JA.

Cell Commun Adhes. 2005 Jul-Dec;12(5-6):307-17.

PMID:
16531325
17.

Oncogenic Kras initiates leukemia in hematopoietic stem cells.

Sabnis AJ, Cheung LS, Dail M, Kang HC, Santaguida M, Hermiston ML, Passegué E, Shannon K, Braun BS.

PLoS Biol. 2009 Mar 17;7(3):e59. doi: 10.1371/journal.pbio.1000059.

18.

RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia.

Kim WI, Matise I, Diers MD, Largaespada DA.

Blood. 2009 Jan 29;113(5):1086-96. doi: 10.1182/blood-2008-01-132316.

19.

A novel hematopoietic multilineage clone, Myl-D-7, is stromal cell-dependent and supported by an alternative mechanism(s) independent of stem cell factor/c-kit interaction.

Itoh K, Friel J, Kluge N, Kina T, Kondo-Takaori A, Kawamata S, Uchiyama T, Ostertag W.

Blood. 1996 Apr 15;87(8):3218-28.

20.

Role of p53 in hematopoietic recovery after cytotoxic treatment.

Wlodarski P, Wasik M, Ratajczak MZ, Sevignani C, Hoser G, Kawiak J, Gewirtz AM, Calabretta B, Skorski T.

Blood. 1998 Apr 15;91(8):2998-3006.

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