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Items: 1 to 20 of 118

1.

Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate.

Lee S, Kang J, Yoo J, Ganesan SK, Cook SC, Aguilar B, Ramu S, Lee J, Hong YK.

Blood. 2009 Feb 19;113(8):1856-9. doi: 10.1182/blood-2008-03-145789. Epub 2008 Sep 24.

2.

An exquisite cross-control mechanism among endothelial cell fate regulators directs the plasticity and heterogeneity of lymphatic endothelial cells.

Kang J, Yoo J, Lee S, Tang W, Aguilar B, Ramu S, Choi I, Otu HH, Shin JW, Dotto GP, Koh CJ, Detmar M, Hong YK.

Blood. 2010 Jul 8;116(1):140-50. doi: 10.1182/blood-2009-11-252270. Epub 2010 Mar 29.

3.

COUP-TFII orchestrates venous and lymphatic endothelial identity by homo- or hetero-dimerisation with PROX1.

Aranguren XL, Beerens M, Coppiello G, Wiese C, Vandersmissen I, Lo Nigro A, Verfaillie CM, Gessler M, Luttun A.

J Cell Sci. 2013 Mar 1;126(Pt 5):1164-75. doi: 10.1242/jcs.116293. Epub 2013 Jan 23.

4.

The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells.

Srinivasan RS, Geng X, Yang Y, Wang Y, Mukatira S, Studer M, Porto MP, Lagutin O, Oliver G.

Genes Dev. 2010 Apr 1;24(7):696-707. doi: 10.1101/gad.1859310.

5.

COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction.

Yamazaki T, Yoshimatsu Y, Morishita Y, Miyazono K, Watabe T.

Genes Cells. 2009 Mar;14(3):425-34. doi: 10.1111/j.1365-2443.2008.01279.x. Epub 2009 Feb 4.

6.

Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves.

Srinivasan RS, Oliver G.

Genes Dev. 2011 Oct 15;25(20):2187-97. doi: 10.1101/gad.16974811.

7.

Divergence of zebrafish and mouse lymphatic cell fate specification pathways.

van Impel A, Zhao Z, Hermkens DM, Roukens MG, Fischer JC, Peterson-Maduro J, Duckers H, Ober EA, Ingham PW, Schulte-Merker S.

Development. 2014 Mar;141(6):1228-38. doi: 10.1242/dev.105031. Epub 2014 Feb 12.

8.

Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate.

Hong YK, Harvey N, Noh YH, Schacht V, Hirakawa S, Detmar M, Oliver G.

Dev Dyn. 2002 Nov;225(3):351-7.

9.

Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development.

Lin FJ, Chen X, Qin J, Hong YK, Tsai MJ, Tsai SY.

J Clin Invest. 2010 May;120(5):1694-707. doi: 10.1172/JCI40101. Epub 2010 Apr 1.

10.

Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity.

Johnson NC, Dillard ME, Baluk P, McDonald DM, Harvey NL, Frase SL, Oliver G.

Genes Dev. 2008 Dec 1;22(23):3282-91. doi: 10.1101/gad.1727208.

11.

Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades.

Mishima K, Watabe T, Saito A, Yoshimatsu Y, Imaizumi N, Masui S, Hirashima M, Morisada T, Oike Y, Araie M, Niwa H, Kubo H, Suda T, Miyazono K.

Mol Biol Cell. 2007 Apr;18(4):1421-9. Epub 2007 Feb 7.

12.

Prox1, master regulator of the lymphatic vasculature phenotype.

Hong YK, Detmar M.

Cell Tissue Res. 2003 Oct;314(1):85-92. Epub 2003 Jul 22. Review.

PMID:
12883994
13.

Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis.

Shin JW, Min M, Larrieu-Lahargue F, Canron X, Kunstfeld R, Nguyen L, Henderson JE, Bikfalvi A, Detmar M, Hong YK.

Mol Biol Cell. 2006 Feb;17(2):576-84. Epub 2005 Nov 16.

14.

Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus.

Yoo J, Lee HN, Choi I, Choi D, Chung HK, Kim KE, Lee S, Aguilar B, Kang J, Park E, Lee YS, Maeng YS, Kim NY, Koh CJ, Hong YK.

PLoS Pathog. 2012;8(6):e1002770. doi: 10.1371/journal.ppat.1002770. Epub 2012 Jun 14.

15.

Transcription factor COUP-TFII is indispensable for venous and lymphatic development in zebrafish and Xenopus laevis.

Aranguren XL, Beerens M, Vandevelde W, Dewerchin M, Carmeliet P, Luttun A.

Biochem Biophys Res Commun. 2011 Jun 24;410(1):121-6. doi: 10.1016/j.bbrc.2011.05.117. Epub 2011 May 27.

PMID:
21641336
16.

The Prox1-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors.

Srinivasan RS, Escobedo N, Yang Y, Interiano A, Dillard ME, Finkelstein D, Mukatira S, Gil HJ, Nurmi H, Alitalo K, Oliver G.

Genes Dev. 2014 Oct 1;28(19):2175-87. doi: 10.1101/gad.216226.113.

17.

BRG1 promotes COUP-TFII expression and venous specification during embryonic vascular development.

Davis RB, Curtis CD, Griffin CT.

Development. 2013 Mar;140(6):1272-81. doi: 10.1242/dev.087379. Epub 2013 Feb 13.

18.

Lymphatic fate determination: playing RAF with ERK.

Deng Y, Simons M.

Cell Cycle. 2013 Apr 15;12(8):1157-8. doi: 10.4161/cc.24491. Epub 2013 Apr 2. No abstract available.

19.

miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo.

Pedrioli DM, Karpanen T, Dabouras V, Jurisic G, van de Hoek G, Shin JW, Marino D, Kälin RE, Leidel S, Cinelli P, Schulte-Merker S, Brändli AW, Detmar M.

Mol Cell Biol. 2010 Jul;30(14):3620-34. doi: 10.1128/MCB.00185-10. Epub 2010 May 17.

20.

Prox1 postmitotically defines dentate gyrus cells by specifying granule cell identity over CA3 pyramidal cell fate in the hippocampus.

Iwano T, Masuda A, Kiyonari H, Enomoto H, Matsuzaki F.

Development. 2012 Aug;139(16):3051-62. doi: 10.1242/dev.080002. Epub 2012 Jul 12.

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