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Fat adaptation followed by carbohydrate restoration increases AMPK activity in skeletal muscle from trained humans.

Yeo WK, Lessard SJ, Chen ZP, Garnham AP, Burke LM, Rivas DA, Kemp BE, Hawley JA.

J Appl Physiol (1985). 2008 Nov;105(5):1519-26. doi: 10.1152/japplphysiol.90540.2008. Epub 2008 Sep 18.


Decreased PDH activation and glycogenolysis during exercise following fat adaptation with carbohydrate restoration.

Stellingwerff T, Spriet LL, Watt MJ, Kimber NE, Hargreaves M, Hawley JA, Burke LM.

Am J Physiol Endocrinol Metab. 2006 Feb;290(2):E380-8. Epub 2005 Sep 27.


Short-term exercise training in humans reduces AMPK signalling during prolonged exercise independent of muscle glycogen.

McConell GK, Lee-Young RS, Chen ZP, Stepto NK, Huynh NN, Stephens TJ, Canny BJ, Kemp BE.

J Physiol. 2005 Oct 15;568(Pt 2):665-76. Epub 2005 Jul 28.


Effect of fat adaptation and carbohydrate restoration on metabolism and performance during prolonged cycling.

Burke LM, Angus DJ, Cox GR, Cummings NK, Febbraio MA, Gawthorn K, Hawley JA, Minehan M, Martin DT, Hargreaves M.

J Appl Physiol (1985). 2000 Dec;89(6):2413-21.


Intensified exercise training does not alter AMPK signaling in human skeletal muscle.

Clark SA, Chen ZP, Murphy KT, Aughey RJ, McKenna MJ, Kemp BE, Hawley JA.

Am J Physiol Endocrinol Metab. 2004 May;286(5):E737-43. Epub 2003 Dec 23.


Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise.

Roepstorff C, Halberg N, Hillig T, Saha AK, Ruderman NB, Wojtaszewski JF, Richter EA, Kiens B.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E133-42. Epub 2004 Sep 21.


Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability.

Burke LM, Hawley JA, Angus DJ, Cox GR, Clark SA, Cummings NK, Desbrow B, Hargreaves M.

Med Sci Sports Exerc. 2002 Jan;34(1):83-91.


Effects of fat adaptation and carbohydrate restoration on prolonged endurance exercise.

Carey AL, Staudacher HM, Cummings NK, Stepto NK, Nikolopoulos V, Burke LM, Hawley JA.

J Appl Physiol (1985). 2001 Jul;91(1):115-22.


High-fat diet overrules the effects of training on fiber-specific intramyocellular lipid utilization during exercise.

Van Proeyen K, Szlufcik K, Nielens H, Deldicque L, Van Dyck R, Ramaekers M, Hespel P.

J Appl Physiol (1985). 2011 Jul;111(1):108-16. doi: 10.1152/japplphysiol.01459.2010. Epub 2011 May 5.


Progressive increase in human skeletal muscle AMPKalpha2 activity and ACC phosphorylation during exercise.

Stephens TJ, Chen ZP, Canny BJ, Michell BJ, Kemp BE, McConell GK.

Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E688-94.


Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle.

Wojtaszewski JF, MacDonald C, Nielsen JN, Hellsten Y, Hardie DG, Kemp BE, Kiens B, Richter EA.

Am J Physiol Endocrinol Metab. 2003 Apr;284(4):E813-22. Epub 2002 Dec 17.


Fat adaptation in well-trained athletes: effects on cell metabolism.

Yeo WK, Carey AL, Burke L, Spriet LL, Hawley JA.

Appl Physiol Nutr Metab. 2011 Feb;36(1):12-22. doi: 10.1139/H10-089. Review.


Intramyocellular lipid stores increase markedly in athletes after 1.5 days lipid supplementation and are utilized during exercise in proportion to their content.

Zehnder M, Christ ER, Ith M, Acheson KJ, Pouteau E, Kreis R, Trepp R, Diem P, Boesch C, Décombaz J.

Eur J Appl Physiol. 2006 Nov;98(4):341-54. Epub 2006 Aug 11.


Carbohydrate ingestion does not alter skeletal muscle AMPK signaling during exercise in humans.

Lee-Young RS, Palmer MJ, Linden KC, LePlastrier K, Canny BJ, Hargreaves M, Wadley GD, Kemp BE, McConell GK.

Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E566-73. Epub 2006 May 2.


Manipulation of dietary carbohydrate and muscle glycogen affects glucose uptake during exercise when fat oxidation is impaired by beta-adrenergic blockade.

Zderic TW, Schenk S, Davidson CJ, Byerley LO, Coyle EF.

Am J Physiol Endocrinol Metab. 2004 Dec;287(6):E1195-201. Epub 2004 Aug 17.


Dissociation of AMPK activity and ACCbeta phosphorylation in human muscle during prolonged exercise.

Wojtaszewski JF, Mourtzakis M, Hillig T, Saltin B, Pilegaard H.

Biochem Biophys Res Commun. 2002 Nov 1;298(3):309-16.


5'-AMP-activated protein kinase activity and protein expression are regulated by endurance training in human skeletal muscle.

Frøsig C, Jørgensen SB, Hardie DG, Richter EA, Wojtaszewski JF.

Am J Physiol Endocrinol Metab. 2004 Mar;286(3):E411-7. Epub 2003 Nov 12.


Short-term high-fat diet alters substrate utilization during exercise but not glucose tolerance in highly trained athletes.

Staudacher HM, Carey AL, Cummings NK, Hawley JA, Burke LM.

Int J Sport Nutr Exerc Metab. 2001 Sep;11(3):273-86.


Carbohydrate refeeding after a high-fat diet rapidly reverses the adaptive increase in human skeletal muscle PDH kinase activity.

Bigrigg JK, Heigenhauser GJ, Inglis JG, LeBlanc PJ, Peters SJ.

Am J Physiol Regul Integr Comp Physiol. 2009 Sep;297(3):R885-91. doi: 10.1152/ajpregu.90604.2008. Epub 2009 Jul 22.


Effect of high-fat and high-carbohydrate diets on pulmonary O2 uptake kinetics during the transition to moderate-intensity exercise.

Raper JA, Love LK, Paterson DH, Peters SJ, Heigenhauser GJ, Kowalchuk JM.

J Appl Physiol (1985). 2014 Dec 1;117(11):1371-9. doi: 10.1152/japplphysiol.00456.2014. Epub 2014 Oct 2.

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