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Items: 1 to 20 of 131


IRF8 regulates B-cell lineage specification, commitment, and differentiation.

Wang H, Lee CH, Qi C, Tailor P, Feng J, Abbasi S, Atsumi T, Morse HC 3rd.

Blood. 2008 Nov 15;112(10):4028-38. doi: 10.1182/blood-2008-01-129049.


IRF8 regulates myeloid and B lymphoid lineage diversification.

Wang H, Morse HC 3rd.

Immunol Res. 2009;43(1-3):109-17. doi: 10.1007/s12026-008-8055-8. Review.


Assembling a gene regulatory network for specification of the B cell fate.

Medina KL, Pongubala JM, Reddy KL, Lancki DW, Dekoter R, Kieslinger M, Grosschedl R, Singh H.

Dev Cell. 2004 Oct;7(4):607-17.


PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment.

Schönheit J, Kuhl C, Gebhardt ML, Klett FF, Riemke P, Scheller M, Huang G, Naumann R, Leutz A, Stocking C, Priller J, Andrade-Navarro MA, Rosenbauer F.

Cell Rep. 2013 May 30;3(5):1617-28. doi: 10.1016/j.celrep.2013.04.007.


Stem cell-specific epigenetic priming and B cell-specific transcriptional activation at the mouse Cd19 locus.

Walter K, Bonifer C, Tagoh H.

Blood. 2008 Sep 1;112(5):1673-82. doi: 10.1182/blood-2008-02-142786.


E2A Antagonizes PU.1 Activity through Inhibition of DNA Binding.

Rogers JH, Owens KS, Kurkewich J, Klopfenstein N, Iyer SR, Simon MC, Dahl R.

Biomed Res Int. 2016;2016:3983686. doi: 10.1155/2016/3983686.


Immunologic regulation of bone development.

Horowitz MC, Lorenzo JA.

Adv Exp Med Biol. 2007;602:47-56.


Positive regulatory domain I (PRDM1) and IRF8/PU.1 counter-regulate MHC class II transactivator (CIITA) expression during dendritic cell maturation.

Smith MA, Wright G, Wu J, Tailor P, Ozato K, Chen X, Wei S, Piskurich JF, Ting JP, Wright KL.

J Biol Chem. 2011 Mar 11;286(10):7893-904. doi: 10.1074/jbc.M110.165431.


IRF8 governs expression of genes involved in innate and adaptive immunity in human and mouse germinal center B cells.

Shin DM, Lee CH, Morse HC 3rd.

PLoS One. 2011;6(11):e27384. doi: 10.1371/journal.pone.0027384.


Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1.

Oguro H, Yuan J, Ichikawa H, Ikawa T, Yamazaki S, Kawamoto H, Nakauchi H, Iwama A.

Cell Stem Cell. 2010 Mar 5;6(3):279-86. doi: 10.1016/j.stem.2010.01.005.


Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development.

Kwon K, Hutter C, Sun Q, Bilic I, Cobaleda C, Malin S, Busslinger M.

Immunity. 2008 Jun;28(6):751-62. doi: 10.1016/j.immuni.2008.04.014.


Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.

Pongubala JM, Northrup DL, Lancki DW, Medina KL, Treiber T, Bertolino E, Thomas M, Grosschedl R, Allman D, Singh H.

Nat Immunol. 2008 Feb;9(2):203-15. doi: 10.1038/ni1555.


Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner.

Åhsberg J, Ungerbäck J, Strid T, Welinder E, Stjernberg J, Larsson M, Qian H, Sigvardsson M.

J Biol Chem. 2013 Nov 15;288(46):33449-61. doi: 10.1074/jbc.M113.506261.


Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage.

Anderson MK, Hernandez-Hoyos G, Diamond RA, Rothenberg EV.

Development. 1999 Jun;126(14):3131-48.


PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.

Venigalla RK, McGuire VA, Clarke R, Patterson-Kane JC, Najafov A, Toth R, McCarthy PC, Simeons F, Stojanovski L, Arthur JS.

EMBO J. 2013 Apr 3;32(7):1008-22. doi: 10.1038/emboj.2013.40.


Gradient of E2A activity in B-cell development.

Herblot S, Aplan PD, Hoang T.

Mol Cell Biol. 2002 Feb;22(3):886-900.


The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.

Carotta S, Willis SN, Hasbold J, Inouye M, Pang SH, Emslie D, Light A, Chopin M, Shi W, Wang H, Morse HC 3rd, Tarlinton DM, Corcoran LM, Hodgkin PD, Nutt SL.

J Exp Med. 2014 Oct 20;211(11):2169-81. doi: 10.1084/jem.20140425.

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