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Items: 1 to 20 of 265

1.

All EGF(ErbB) receptors have preformed homo- and heterodimeric structures in living cells.

Tao RH, Maruyama IN.

J Cell Sci. 2008 Oct 1;121(Pt 19):3207-17. doi: 10.1242/jcs.033399. Epub 2008 Sep 9.

2.

Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis.

Clayton AH, Walker F, Orchard SG, Henderson C, Fuchs D, Rothacker J, Nice EC, Burgess AW.

J Biol Chem. 2005 Aug 26;280(34):30392-9. Epub 2005 Jun 30.

3.

The ErbB/HER receptor protein-tyrosine kinases and cancer.

Roskoski R Jr.

Biochem Biophys Res Commun. 2004 Jun 18;319(1):1-11. Review.

PMID:
15158434
4.

Epidermal growth factor receptor (EGFR) signaling in cancer.

Normanno N, De Luca A, Bianco C, Strizzi L, Mancino M, Maiello MR, Carotenuto A, De Feo G, Caponigro F, Salomon DS.

Gene. 2006 Jan 17;366(1):2-16. Epub 2005 Dec 27. Review.

PMID:
16377102
5.

Bivalence of EGF-like ligands drives the ErbB signaling network.

Tzahar E, Pinkas-Kramarski R, Moyer JD, Klapper LN, Alroy I, Levkowitz G, Shelly M, Henis S, Eisenstein M, Ratzkin BJ, Sela M, Andrews GC, Yarden Y.

EMBO J. 1997 Aug 15;16(16):4938-50.

6.

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity.

Kochupurakkal BS, Harari D, Di-Segni A, Maik-Rachline G, Lyass L, Gur G, Kerber G, Citri A, Lavi S, Eilam R, Chalifa-Caspi V, Eshhar Z, Pikarsky E, Pinkas-Kramarski R, Bacus SS, Yarden Y.

J Biol Chem. 2005 Mar 4;280(9):8503-12. Epub 2004 Dec 17.

7.
8.

Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.

Ghiglione C, Amundadottir L, Andresdottir M, Bilder D, Diamonti JA, Noselli S, Perrimon N, Carraway III KL.

Development. 2003 Sep;130(18):4483-93.

9.

Epiregulin is a potent pan-ErbB ligand that preferentially activates heterodimeric receptor complexes.

Shelly M, Pinkas-Kramarski R, Guarino BC, Waterman H, Wang LM, Lyass L, Alimandi M, Kuo A, Bacus SS, Pierce JH, Andrews GC, Yarden Y.

J Biol Chem. 1998 Apr 24;273(17):10496-505.

10.
11.

Differential and synergistic effects of epidermal growth factor receptor antibodies on unliganded ErbB dimers and oligomers.

Kozer N, Kelly MP, Orchard S, Burgess AW, Scott AM, Clayton AH.

Biochemistry. 2011 May 10;50(18):3581-90. doi: 10.1021/bi101785h. Epub 2011 Apr 15.

PMID:
21495621
12.

The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases.

Laederich MB, Funes-Duran M, Yen L, Ingalla E, Wu X, Carraway KL 3rd, Sweeney C.

J Biol Chem. 2004 Nov 5;279(45):47050-6. Epub 2004 Sep 1.

13.

Active and inactive conformations of the epidermal growth factor receptor.

Ferguson KM.

Biochem Soc Trans. 2004 Nov;32(Pt 5):742-5. Review.

PMID:
15494003
14.

Oligomers of ERBB3 have two distinct interfaces that differ in their sensitivity to disruption by heregulin.

Kani K, Warren CM, Kaddis CS, Loo JA, Landgraf R.

J Biol Chem. 2005 Mar 4;280(9):8238-47. Epub 2004 Dec 20.

15.

Nerve growth factor receptor TrkA exists as a preformed, yet inactive, dimer in living cells.

Shen J, Maruyama IN.

FEBS Lett. 2011 Jan 21;585(2):295-9. doi: 10.1016/j.febslet.2010.12.031. Epub 2010 Dec 25.

16.

Quantum dot ligands provide new insights into erbB/HER receptor-mediated signal transduction.

Lidke DS, Nagy P, Heintzmann R, Arndt-Jovin DJ, Post JN, Grecco HE, Jares-Erijman EA, Jovin TM.

Nat Biotechnol. 2004 Feb;22(2):198-203. Epub 2004 Jan 4.

PMID:
14704683
17.

Distribution of resting and ligand-bound ErbB1 and ErbB2 receptor tyrosine kinases in living cells using number and brightness analysis.

Nagy P, Claus J, Jovin TM, Arndt-Jovin DJ.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16524-9. doi: 10.1073/pnas.1002642107. Epub 2010 Sep 2.

18.

Disabling receptor ensembles with rationally designed interface peptidomimetics.

Berezov A, Chen J, Liu Q, Zhang HT, Greene MI, Murali R.

J Biol Chem. 2002 Aug 2;277(31):28330-9. Epub 2002 May 14.

19.

Control of ErbB signaling through metalloprotease mediated ectodomain shedding of EGF-like factors.

Sanderson MP, Dempsey PJ, Dunbar AJ.

Growth Factors. 2006 Jun;24(2):121-36. Review.

PMID:
16801132
20.

Evolutionary analysis of the ErbB receptor and ligand families.

Stein RA, Staros JV.

J Mol Evol. 2000 May;50(5):397-412.

PMID:
10824084

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