Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 52

1.

Mdm2 induces mono-ubiquitination of FOXO4.

Brenkman AB, de Keizer PL, van den Broek NJ, Jochemsen AG, Burgering BM.

PLoS One. 2008 Jul 30;3(7):e2819. doi: 10.1371/journal.pone.0002819.

2.

MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation.

Fu W, Ma Q, Chen L, Li P, Zhang M, Ramamoorthy S, Nawaz Z, Shimojima T, Wang H, Yang Y, Shen Z, Zhang Y, Zhang X, Nicosia SV, Zhang Y, Pledger JW, Chen J, Bai W.

J Biol Chem. 2009 May 22;284(21):13987-4000. doi: 10.1074/jbc.M901758200. Epub 2009 Mar 25.

3.

Regulation of FOXO protein stability via ubiquitination and proteasome degradation.

Huang H, Tindall DJ.

Biochim Biophys Acta. 2011 Nov;1813(11):1961-4. doi: 10.1016/j.bbamcr.2011.01.007. Epub 2011 Jan 14. Review.

4.

The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressors.

Brenkman AB, de Keizer PL, van den Broek NJ, van der Groep P, van Diest PJ, van der Horst A, Smits AM, Burgering BM.

Cancer Res. 2008 Sep 15;68(18):7597-605. doi: 10.1158/0008-5472.CAN-08-1059.

5.

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP.

van der Horst A, de Vries-Smits AM, Brenkman AB, van Triest MH, van den Broek N, Colland F, Maurice MM, Burgering BM.

Nat Cell Biol. 2006 Oct;8(10):1064-73. Epub 2006 Sep 10.

PMID:
16964248
6.

Dual-site regulation of MDM2 E3-ubiquitin ligase activity.

Wallace M, Worrall E, Pettersson S, Hupp TR, Ball KL.

Mol Cell. 2006 Jul 21;23(2):251-63.

7.

Retinoblastoma protein modulates gankyrin-MDM2 in regulation of p53 stability and chemosensitivity in cancer cells.

Qiu W, Wu J, Walsh EM, Zhang Y, Chen CY, Fujita J, Xiao ZX.

Oncogene. 2008 Jul 3;27(29):4034-43. doi: 10.1038/onc.2008.43. Epub 2008 Mar 10.

PMID:
18332869
8.

Identification of a mechanism underlying regulation of the anti-angiogenic forkhead transcription factor FoxO1 in cultured endothelial cells and ischemic muscle.

Milkiewicz M, Roudier E, Doyle JL, Trifonova A, Birot O, Haas TL.

Am J Pathol. 2011 Feb;178(2):935-44. doi: 10.1016/j.ajpath.2010.10.042.

9.

Oxidative stress-dependent regulation of Forkhead box O4 activity by nemo-like kinase.

Szypowska AA, de Ruiter H, Meijer LA, Smits LM, Burgering BM.

Antioxid Redox Signal. 2011 Feb 15;14(4):563-78. doi: 10.1089/ars.2010.3243. Epub 2010 Nov 23.

PMID:
20874444
10.

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo.

Saville MK, Sparks A, Xirodimas DP, Wardrop J, Stevenson LF, Bourdon JC, Woods YL, Lane DP.

J Biol Chem. 2004 Oct 1;279(40):42169-81. Epub 2004 Jul 26.

11.

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins.

Tzivion G, Dobson M, Ramakrishnan G.

Biochim Biophys Acta. 2011 Nov;1813(11):1938-45. doi: 10.1016/j.bbamcr.2011.06.002. Epub 2011 Jun 17. Review.

12.

Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis.

Sehat B, Andersson S, Girnita L, Larsson O.

Cancer Res. 2008 Jul 15;68(14):5669-77. doi: 10.1158/0008-5472.CAN-07-6364.

13.

Mdm2 and PCAF increase Chk2 ubiquitination and degradation independently of their intrinsic E3 ligase activities.

Kass EM, Poyurovsky MV, Zhu Y, Prives C.

Cell Cycle. 2009 Feb 1;8(3):430-7. Epub 2009 Feb 12.

PMID:
19176998
14.

The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex.

Song MS, Song SJ, Kim SY, Oh HJ, Lim DS.

EMBO J. 2008 Jul 9;27(13):1863-74. doi: 10.1038/emboj.2008.115. Epub 2008 Jun 19.

15.

Src phosphorylation converts Mdm2 from a ubiquitinating to a neddylating E3 ligase.

Batuello CN, Hauck PM, Gendron JM, Lehman JA, Mayo LD.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1749-54. doi: 10.1073/pnas.1416656112. Epub 2015 Jan 26.

16.

Ribosomal protein S7 regulates arsenite-induced GADD45α expression by attenuating MDM2-mediated GADD45α ubiquitination and degradation.

Gao M, Li X, Dong W, Jin R, Ma H, Yang P, Hu M, Li Y, Hao Y, Yuan S, Huang J, Song L.

Nucleic Acids Res. 2013 May 1;41(10):5210-22. doi: 10.1093/nar/gkt223. Epub 2013 Apr 5.

17.

FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).

Kloet DE, Polderman PE, Eijkelenboom A, Smits LM, van Triest MH, van den Berg MC, Groot Koerkamp MJ, van Leenen D, Lijnzaad P, Holstege FC, Burgering BM.

Biochem J. 2015 Jul 15;469(2):289-98. doi: 10.1042/BJ20140831. Epub 2015 May 20.

18.

SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination.

Lee MH, Lee SW, Lee EJ, Choi SJ, Chung SS, Lee JI, Cho JM, Seol JH, Baek SH, Kim KI, Chiba T, Tanaka K, Bang OS, Chung CH.

Nat Cell Biol. 2006 Dec;8(12):1424-31. Epub 2006 Nov 5.

PMID:
17086174
19.

Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination.

Bonacci T, Audebert S, Camoin L, Baudelet E, Iovanna JL, Soubeyran P.

PLoS One. 2017 Jan 18;12(1):e0169988. doi: 10.1371/journal.pone.0169988. eCollection 2017.

20.

Dynamics in the p53-Mdm2 ubiquitination pathway.

Brooks CL, Gu W.

Cell Cycle. 2004 Jul;3(7):895-9. Epub 2004 Jul 2. Review.

PMID:
15254415

Supplemental Content

Support Center