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Items: 1 to 20 of 66

1.

Amyloid precursor protein trafficking, processing, and function.

Thinakaran G, Koo EH.

J Biol Chem. 2008 Oct 31;283(44):29615-9. doi: 10.1074/jbc.R800019200. Epub 2008 Jul 23. Review.

2.

Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments.

Vetrivel KS, Thinakaran G.

Neurology. 2006 Jan 24;66(2 Suppl 1):S69-73. Review.

PMID:
16432149
3.

Intracellular trafficking of the β-secretase and processing of amyloid precursor protein.

Chia PZ, Gleeson PA.

IUBMB Life. 2011 Sep;63(9):721-9. doi: 10.1002/iub.512. Epub 2011 Aug 10. Review. Erratum in: IUBMB Life. 2011 Nov;63(11):1045. Zhi, Pei [removed]; Chia, Cheryl [corrected to Chia, Pei Zhi Cheryl].

4.

Alzheimer's disease.

De-Paula VJ, Radanovic M, Diniz BS, Forlenza OV.

Subcell Biochem. 2012;65:329-52. doi: 10.1007/978-94-007-5416-4_14. Review.

PMID:
23225010
5.

Specific antibody binding to the APP672-699 region shifts APP processing from α- to β-cleavage.

Li S, Deng J, Hou H, Tian J, Giunta B, Wang Y, Sawmiller D, Smith A, Sanberg PR, Obregon D, Mori T, Tan J.

Cell Death Dis. 2014 Aug 14;5:e1374. doi: 10.1038/cddis.2014.336.

6.

Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation.

Lakshmana MK, Yoon IS, Chen E, Bianchi E, Koo EH, Kang DE.

J Biol Chem. 2009 May 1;284(18):11863-72. doi: 10.1074/jbc.M807345200. Epub 2009 Feb 27.

7.

The role of TMP21 in trafficking and amyloid-β precursor protein (APP) processing in Alzheimer's disease.

Bromley-Brits K, Song W.

Curr Alzheimer Res. 2012 May;9(4):411-24. Review.

PMID:
22299712
8.

Localization and Trafficking of Amyloid-β Protein Precursor and Secretases: Impact on Alzheimer's Disease.

Agostinho P, Pliássova A, Oliveira CR, Cunha RA.

J Alzheimers Dis. 2015;45(2):329-47. doi: 10.3233/JAD-142730. Review.

PMID:
25589722
9.

[Alzheimer disease: cellular and molecular aspects].

Octave JN.

Bull Mem Acad R Med Belg. 2005;160(10-12):445-9; discussion 450-1. French.

PMID:
16768248
10.

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production.

Herskowitz JH, Offe K, Deshpande A, Kahn RA, Levey AI, Lah JJ.

Mol Biol Cell. 2012 Jul;23(14):2645-57. doi: 10.1091/mbc.E12-01-0014. Epub 2012 May 23.

11.

Sorting receptor SORLA--a trafficking path to avoid Alzheimer disease.

Willnow TE, Andersen OM.

J Cell Sci. 2013 Jul 1;126(Pt 13):2751-60. doi: 10.1242/jcs.125393. Epub 2013 Jun 26. Review.

12.

Regulation of amyloid beta-protein precursor by phosphorylation and protein interactions.

Suzuki T, Nakaya T.

J Biol Chem. 2008 Oct 31;283(44):29633-7. doi: 10.1074/jbc.R800003200. Epub 2008 Jul 23. Review.

13.

Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.

Deng Y, Wang Z, Wang R, Zhang X, Zhang S, Wu Y, Staufenbiel M, Cai F, Song W.

Eur J Neurosci. 2013 Jun;37(12):1962-9. doi: 10.1111/ejn.12235.

PMID:
23773065
15.

Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.

Evin G, Zhu A, Holsinger RM, Masters CL, Li QX.

J Neurosci Res. 2003 Nov 1;74(3):386-92.

PMID:
14598315
16.

Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.

Wiltfang J, Esselmann H, Cupers P, Neumann M, Kretzschmar H, Beyermann M, Schleuder D, Jahn H, Rüther E, Kornhuber J, Annaert W, De Strooper B, Saftig P.

J Biol Chem. 2001 Nov 16;276(46):42645-57. Epub 2001 Aug 28.

17.

Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein.

Maloney JA, Bainbridge T, Gustafson A, Zhang S, Kyauk R, Steiner P, van der Brug M, Liu Y, Ernst JA, Watts RJ, Atwal JK.

J Biol Chem. 2014 Nov 7;289(45):30990-1000. doi: 10.1074/jbc.M114.589069. Epub 2014 Sep 24.

18.

Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation.

Obregon D, Hou H, Deng J, Giunta B, Tian J, Darlington D, Shahaduzzaman M, Zhu Y, Mori T, Mattson MP, Tan J.

Nat Commun. 2012 Apr 10;3:777. doi: 10.1038/ncomms1781.

19.

[Recent advances in Alzheimer's disease research--amyloid precursor protein trafficking, processing, and mutations in Alzheimer's disease linked genes].

Fukatsu R, Tsuzuki K, Hayashi Y, Takamaru Y, Sasaki N, Yoshida T, Hatakeyama Y, Fuji N, Takahata N.

Hokkaido Igaku Zasshi. 1997 Jan;72(1):3-11. Review. Japanese.

PMID:
9086357
20.

The amyloid peptide precursor in Alzheimer's disease.

Octave JN.

Acta Neurol Belg. 1995 Dec;95(4):197-209. Review.

PMID:
8553793

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