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Items: 1 to 20 of 141


Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans.

Driver EC, Pryor SP, Hill P, Turner J, Rüther U, Biesecker LG, Griffith AJ, Kelley MW.

J Neurosci. 2008 Jul 16;28(29):7350-8. doi: 10.1523/JNEUROSCI.0312-08.2008.


Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea.

Tateya T, Imayoshi I, Tateya I, Hamaguchi K, Torii H, Ito J, Kageyama R.

Development. 2013 Sep;140(18):3848-57. doi: 10.1242/dev.095398. Epub 2013 Aug 14.


Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling.

Benito-Gonzalez A, Doetzlhofer A.

J Neurosci. 2014 Sep 17;34(38):12865-76. doi: 10.1523/JNEUROSCI.1494-14.2014.


Rbpj regulates development of prosensory cells in the mammalian inner ear.

Yamamoto N, Chang W, Kelley MW.

Dev Biol. 2011 May 15;353(2):367-79. doi: 10.1016/j.ydbio.2011.03.016. Epub 2011 Mar 21.


In vivo overactivation of the Notch signaling pathway in the developing cochlear epithelium.

Tateya T, Sakamoto S, Imayoshi I, Kageyama R.

Hear Res. 2015 Sep;327:209-17. doi: 10.1016/j.heares.2015.07.012. Epub 2015 Jul 22.


Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa.

Basch ML, Ohyama T, Segil N, Groves AK.

J Neurosci. 2011 Jun 1;31(22):8046-58. doi: 10.1523/JNEUROSCI.6671-10.2011.


MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear.

Haque K, Pandey AK, Zheng HW, Riazuddin S, Sha SH, Puligilla C.

J Neurosci. 2016 Jan 27;36(4):1347-61. doi: 10.1523/JNEUROSCI.1853-15.2016.


Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development.

Tateya T, Imayoshi I, Tateya I, Ito J, Kageyama R.

Dev Biol. 2011 Apr 15;352(2):329-40. doi: 10.1016/j.ydbio.2011.01.038. Epub 2011 Feb 16.


Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea.

Okano T, Xuan S, Kelley MW.

J Neurosci. 2011 Dec 7;31(49):18104-18. doi: 10.1523/JNEUROSCI.3619-11.2011.


BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea.

Ohyama T, Basch ML, Mishina Y, Lyons KM, Segil N, Groves AK.

J Neurosci. 2010 Nov 10;30(45):15044-51. doi: 10.1523/JNEUROSCI.3547-10.2010.


GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells.

Cain JE, Islam E, Haxho F, Chen L, Bridgewater D, Nieuwenhuis E, Hui CC, Rosenblum ND.

PLoS One. 2009 Oct 7;4(10):e7313. doi: 10.1371/journal.pone.0007313.


Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development.

Brown AS, Epstein DJ.

Development. 2011 Sep;138(18):3967-76. doi: 10.1242/dev.066126. Epub 2011 Aug 10.


Genetic analysis of Hedgehog signaling in ventral body wall development and the onset of omphalocele formation.

Matsumaru D, Haraguchi R, Miyagawa S, Motoyama J, Nakagata N, Meijlink F, Yamada G.

PLoS One. 2011 Jan 20;6(1):e16260. doi: 10.1371/journal.pone.0016260.


Hedgehog signaling governs the development of otic sensory epithelium and its associated innervation in zebrafish.

Sapède D, Pujades C.

J Neurosci. 2010 Mar 10;30(10):3612-23. doi: 10.1523/JNEUROSCI.5109-09.2010.


The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea.

Golden EJ, Benito-Gonzalez A, Doetzlhofer A.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3864-73. doi: 10.1073/pnas.1501077112. Epub 2015 Jul 2.


The Gli3 transcription factor expressed in the thymus stroma controls thymocyte negative selection via Hedgehog-dependent and -independent mechanisms.

Hager-Theodorides AL, Furmanski AL, Ross SE, Outram SV, Rowbotham NJ, Crompton T.

J Immunol. 2009 Sep 1;183(5):3023-32. doi: 10.4049/jimmunol.0900152. Epub 2009 Aug 10.


A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea.

Jacques BE, Puligilla C, Weichert RM, Ferrer-Vaquer A, Hadjantonakis AK, Kelley MW, Dabdoub A.

Development. 2012 Dec 1;139(23):4395-404. doi: 10.1242/dev.080358.


Hedgehog pathway activity in the LADY prostate tumor model.

Gipp J, Gu G, Crylen C, Kasper S, Bushman W.

Mol Cancer. 2007 Mar 7;6:19.


Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells.

Dakubo GD, Beug ST, Mazerolle CJ, Thurig S, Wang Y, Wallace VA.

Brain Res. 2008 Sep 4;1228:27-42. doi: 10.1016/j.brainres.2008.06.058. Epub 2008 Jun 24.


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