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Items: 1 to 20 of 225

1.

NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly.

Gilchrist DA, Nechaev S, Lee C, Ghosh SK, Collins JB, Li L, Gilmour DS, Adelman K.

Genes Dev. 2008 Jul 15;22(14):1921-33. doi: 10.1101/gad.1643208.

2.

NELF and GAGA factor are linked to promoter-proximal pausing at many genes in Drosophila.

Lee C, Li X, Hechmer A, Eisen M, Biggin MD, Venters BJ, Jiang C, Li J, Pugh BF, Gilmour DS.

Mol Cell Biol. 2008 May;28(10):3290-300. doi: 10.1128/MCB.02224-07. Epub 2008 Mar 10.

3.

Kinetic competition between elongation rate and binding of NELF controls promoter-proximal pausing.

Li J, Liu Y, Rhee HS, Ghosh SK, Bai L, Pugh BF, Gilmour DS.

Mol Cell. 2013 Jun 6;50(5):711-22. doi: 10.1016/j.molcel.2013.05.016.

4.

Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex.

Missra A, Gilmour DS.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11301-6. doi: 10.1073/pnas.1000681107. Epub 2010 Jun 4.

5.

Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription.

Ardehali MB, Mei A, Zobeck KL, Caron M, Lis JT, Kusch T.

EMBO J. 2011 Jun 21;30(14):2817-28. doi: 10.1038/emboj.2011.194.

6.

NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila.

Wu CH, Yamaguchi Y, Benjamin LR, Horvat-Gordon M, Washinsky J, Enerly E, Larsson J, Lambertsson A, Handa H, Gilmour D.

Genes Dev. 2003 Jun 1;17(11):1402-14.

7.

NELF potentiates gene transcription in the Drosophila embryo.

Wang X, Hang S, Prazak L, Gergen JP.

PLoS One. 2010 Jul 9;5(7):e11498. doi: 10.1371/journal.pone.0011498.

8.
9.

Defining the status of RNA polymerase at promoters.

Core LJ, Waterfall JJ, Gilchrist DA, Fargo DC, Kwak H, Adelman K, Lis JT.

Cell Rep. 2012 Oct 25;2(4):1025-35. doi: 10.1016/j.celrep.2012.08.034. Epub 2012 Oct 10.

10.

CBP Regulates Recruitment and Release of Promoter-Proximal RNA Polymerase II.

Boija A, Mahat DB, Zare A, Holmqvist PH, Philip P, Meyers DJ, Cole PA, Lis JT, Stenberg P, Mannervik M.

Mol Cell. 2017 Nov 2;68(3):491-503.e5. doi: 10.1016/j.molcel.2017.09.031. Epub 2017 Oct 19.

PMID:
29056321
11.

Promoter elements associated with RNA Pol II stalling in the Drosophila embryo.

Hendrix DA, Hong JW, Zeitlinger J, Rokhsar DS, Levine MS.

Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7762-7. doi: 10.1073/pnas.0802406105. Epub 2008 May 27.

12.

Negative elongation factor NELF represses human immunodeficiency virus transcription by pausing the RNA polymerase II complex.

Zhang Z, Klatt A, Gilmour DS, Henderson AJ.

J Biol Chem. 2007 Jun 8;282(23):16981-8. Epub 2007 Apr 18.

13.

Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling.

Adelman K, Kennedy MA, Nechaev S, Gilchrist DA, Muse GW, Chinenov Y, Rogatsky I.

Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18207-12. doi: 10.1073/pnas.0910177106. Epub 2009 Oct 9.

14.

Regulation of snRNA gene expression by the Drosophila melanogaster small nuclear RNA activating protein complex (DmSNAPc).

Hung KH, Stumph WE.

Crit Rev Biochem Mol Biol. 2011 Feb;46(1):11-26. doi: 10.3109/10409238.2010.518136. Epub 2010 Oct 6. Review.

PMID:
20925482
15.

Human negative elongation factor activates transcription and regulates alternative transcription initiation.

Sun J, Li R.

J Biol Chem. 2010 Feb 26;285(9):6443-52. doi: 10.1074/jbc.M109.084285. Epub 2009 Dec 22.

16.

Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription.

Natarajan M, Schiralli Lester GM, Lee C, Missra A, Wasserman GA, Steffen M, Gilmour DS, Henderson AJ.

J Biol Chem. 2013 Sep 6;288(36):25995-6003. doi: 10.1074/jbc.M113.496489. Epub 2013 Jul 24.

17.

Defining NELF-E RNA binding in HIV-1 and promoter-proximal pause regions.

Pagano JM, Kwak H, Waters CT, Sprouse RO, White BS, Ozer A, Szeto K, Shalloway D, Craighead HG, Lis JT.

PLoS Genet. 2014 Jan;10(1):e1004090. doi: 10.1371/journal.pgen.1004090. Epub 2014 Jan 16.

18.

The heat shock response: A case study of chromatin dynamics in gene regulation.

Teves SS, Henikoff S.

Biochem Cell Biol. 2013 Feb;91(1):42-8. doi: 10.1139/bcb-2012-0075. Epub 2013 Feb 13. Review.

PMID:
23442140
19.

Negative elongation factor accelerates the rate at which heat shock genes are shut off by facilitating dissociation of heat shock factor.

Ghosh SK, Missra A, Gilmour DS.

Mol Cell Biol. 2011 Oct;31(20):4232-43. doi: 10.1128/MCB.05930-11. Epub 2011 Aug 22.

20.

RNA polymerase is poised for activation across the genome.

Muse GW, Gilchrist DA, Nechaev S, Shah R, Parker JS, Grissom SF, Zeitlinger J, Adelman K.

Nat Genet. 2007 Dec;39(12):1507-11. Epub 2007 Nov 11.

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