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cAMP-dependent protein kinase A (PKA) signaling induces TNFR1 exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to BIG2.

Islam A, Jones H, Hiroi T, Lam J, Zhang J, Moss J, Vaughan M, Levine SJ.

J Biol Chem. 2008 Sep 12;283(37):25364-71. doi: 10.1074/jbc.M804966200. Epub 2008 Jul 14.


The brefeldin A-inhibited guanine nucleotide-exchange protein, BIG2, regulates the constitutive release of TNFR1 exosome-like vesicles.

Islam A, Shen X, Hiroi T, Moss J, Vaughan M, Levine SJ.

J Biol Chem. 2007 Mar 30;282(13):9591-9. Epub 2007 Feb 2.


Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma.

Kuroda F, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3201-6. Epub 2007 Feb 21.


Protein kinase A-anchoring (AKAP) domains in brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2).

Li H, Adamik R, Pacheco-Rodriguez G, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1627-32. Epub 2003 Feb 5.


Extracellular TNFR1 release requires the calcium-dependent formation of a nucleobindin 2-ARTS-1 complex.

Islam A, Adamik B, Hawari FI, Ma G, Rouhani FN, Zhang J, Levine SJ.

J Biol Chem. 2006 Mar 10;281(10):6860-73. Epub 2006 Jan 5.


Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals.

Li CC, Le K, Kato J, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):5946-51. doi: 10.1073/pnas.1601918113. Epub 2016 May 9.


Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity.

Puxeddu E, Uhart M, Li CC, Ahmad F, Pacheco-Rodriguez G, Manganiello VC, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6158-63. doi: 10.1073/pnas.0901558106. Epub 2009 Mar 30.


An association between RBMX, a heterogeneous nuclear ribonucleoprotein, and ARTS-1 regulates extracellular TNFR1 release.

Adamik B, Islam A, Rouhani FN, Hawari FI, Zhang J, Levine SJ.

Biochem Biophys Res Commun. 2008 Jul 4;371(3):505-9. doi: 10.1016/j.bbrc.2008.04.103. Epub 2008 Apr 28.


Identification of cAMP-dependent protein kinase holoenzymes in preantral- and preovulatory-follicle-enriched ovaries, and their association with A-kinase-anchoring proteins.

Carr DW, Cutler RE Jr, Cottom JE, Salvador LM, Fraser ID, Scott JD, Hunzicker-Dunn M.

Biochem J. 1999 Dec 1;344 Pt 2:613-23.


The differential response of protein kinase A to cyclic AMP in discrete brain areas correlates with the abundance of regulatory subunit II.

Ventra C, Porcellini A, Feliciello A, Gallo A, Paolillo M, Mele E, Avvedimento VE, Schettini G.

J Neurochem. 1996 Apr;66(4):1752-61.


Cyclic AMP and AKAP-mediated targeting of protein kinase A regulates lactate dehydrogenase subunit A mRNA stability.

Jungmann RA, Kiryukhina O.

J Biol Chem. 2005 Jul 1;280(26):25170-7. Epub 2005 May 5.


Effect of protein kinase A on accumulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) in HepG2 cell nuclei.

Citterio C, Jones HD, Pacheco-Rodriguez G, Islam A, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2683-8. Epub 2006 Feb 8.


Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex.

Diviani D, Abuin L, Cotecchia S, Pansier L.

EMBO J. 2004 Jul 21;23(14):2811-20. Epub 2004 Jul 1.


The roles of the RIIβ linker and N-terminal cyclic nucleotide-binding domain in determining the unique structures of the type IIβ protein kinase A: a small angle x-ray and neutron scattering study.

Blumenthal DK, Copps J, Smith-Nguyen EV, Zhang P, Heller WT, Taylor SS.

J Biol Chem. 2014 Oct 10;289(41):28505-12. doi: 10.1074/jbc.M114.584177. Epub 2014 Aug 11.


Circulating TNFR1 exosome-like vesicles partition with the LDL fraction of human plasma.

Zhang J, Hawari FI, Shamburek RD, Adamik B, Kaler M, Islam A, Liao DW, Rouhani FN, Ingham M, Levine SJ.

Biochem Biophys Res Commun. 2008 Feb 8;366(2):579-84. Epub 2007 Dec 17.


The RIIbeta regulatory subunit of protein kinase A binds to cAMP response element: an alternative cAMP signaling pathway.

Srivastava RK, Lee YN, Noguchi K, Park YG, Ellis MJ, Jeong JS, Kim SN, Cho-Chung YS.

Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6687-92.

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