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Items: 1 to 20 of 81

1.

Intestinal deletion of Pofut1 in the mouse inactivates notch signaling and causes enterocolitis.

Guilmeau S, Flandez M, Bancroft L, Sellers RS, Tear B, Stanley P, Augenlicht LH.

Gastroenterology. 2008 Sep;135(3):849-60, 860.e1-6. doi: 10.1053/j.gastro.2008.05.050.

2.

Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions.

Yao D, Huang Y, Huang X, Wang W, Yan Q, Wei L, Xin W, Gerson S, Stanley P, Lowe JB, Zhou L.

Blood. 2011 May 26;117(21):5652-62. doi: 10.1182/blood-2010-12-326074.

3.

Roles of Pofut1 and O-fucose in mammalian Notch signaling.

Stahl M, Uemura K, Ge C, Shi S, Tashima Y, Stanley P.

J Biol Chem. 2008 May 16;283(20):13638-51. doi: 10.1074/jbc.M802027200.

4.

Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development.

Schuster-Gossler K, Harris B, Johnson KR, Serth J, Gossler A.

BMC Dev Biol. 2009 Jan 22;9:6. doi: 10.1186/1471-213X-9-6.

5.

Notch signaling controls the balance of ciliated and secretory cell fates in developing airways.

Tsao PN, Vasconcelos M, Izvolsky KI, Qian J, Lu J, Cardoso WV.

Development. 2009 Jul;136(13):2297-307. doi: 10.1242/dev.034884.

6.

Secretory cell hyperplasia and defects in Notch activity in a mouse model of leukocyte adhesion deficiency type II.

Waterhouse CC, Johnson S, Phillipson M, Zbytnuik L, Petri B, Kelly M, Lowe JB, Kubes P.

Gastroenterology. 2010 Mar;138(3):1079-90.e1-5. doi: 10.1053/j.gastro.2009.10.049.

PMID:
19900444
7.

Overexpression of protein O-fucosyltransferase 1 accelerates hepatocellular carcinoma progression via the Notch signaling pathway.

Ma L, Dong P, Liu L, Gao Q, Duan M, Zhang S, Chen S, Xue R, Wang X.

Biochem Biophys Res Commun. 2016 Apr 29;473(2):503-10. doi: 10.1016/j.bbrc.2016.03.062.

PMID:
27003260
8.

Protein O-fucosyltransferase 1 expression impacts myogenic C2C12 cell commitment via the Notch signaling pathway.

Der Vartanian A, Audfray A, Al Jaam B, Janot M, Legardinier S, Maftah A, Germot A.

Mol Cell Biol. 2015 Jan;35(2):391-405. doi: 10.1128/MCB.00890-14.

9.

O-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand function.

Müller J, Rana NA, Serth K, Kakuda S, Haltiwanger RS, Gossler A.

PLoS One. 2014 Feb 12;9(2):e88571. doi: 10.1371/journal.pone.0088571.

10.

Epithelial cell-intrinsic Notch signaling plays an essential role in the maintenance of gut immune homeostasis.

Obata Y, Takahashi D, Ebisawa M, Kakiguchi K, Yonemura S, Jinnohara T, Kanaya T, Fujimura Y, Ohmae M, Hase K, Ohno H.

J Immunol. 2012 Mar 1;188(5):2427-36. doi: 10.4049/jimmunol.1101128.

11.

Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.

Tsao PN, Wei SC, Wu MF, Huang MT, Lin HY, Lee MC, Lin KM, Wang IJ, Kaartinen V, Yang LT, Cardoso WV.

Development. 2011 Aug;138(16):3533-43. doi: 10.1242/dev.063727.

12.

Notch signaling is required for the maintenance of enteric neural crest progenitors.

Okamura Y, Saga Y.

Development. 2008 Nov;135(21):3555-65. doi: 10.1242/dev.022319.

13.

SOX9 is required for the differentiation of paneth cells in the intestinal epithelium.

Mori-Akiyama Y, van den Born M, van Es JH, Hamilton SR, Adams HP, Zhang J, Clevers H, de Crombrugghe B.

Gastroenterology. 2007 Aug;133(2):539-46.

PMID:
17681175
14.

Notch signaling regulates late-stage epidermal differentiation and maintains postnatal hair cycle homeostasis.

Lin HY, Kao CH, Lin KM, Kaartinen V, Yang LT.

PLoS One. 2011 Jan 18;6(1):e15842. doi: 10.1371/journal.pone.0015842.

15.

Pofut1 is required for the proper localization of the Notch receptor during mouse development.

Okamura Y, Saga Y.

Mech Dev. 2008 Aug;125(8):663-73. doi: 10.1016/j.mod.2008.04.007.

16.

O-fucose modulates Notch-controlled blood lineage commitment.

Yan Q, Yao D, Wei LL, Huang Y, Myers J, Zhang L, Xin W, Shim J, Man Y, Petryniak B, Gerson S, Lowe JB, Zhou L.

Am J Pathol. 2010 Jun;176(6):2921-34. doi: 10.2353/ajpath.2010.090702.

17.
18.

Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues.

Obata Y, Kimura S, Nakato G, Iizuka K, Miyagawa Y, Nakamura Y, Furusawa Y, Sugiyama M, Suzuki K, Ebisawa M, Fujimura Y, Yoshida H, Iwanaga T, Hase K, Ohno H.

EMBO Rep. 2014 Dec;15(12):1297-304. doi: 10.15252/embr.201438942.

19.

Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation.

Feng Y, Sentani K, Wiese A, Sands E, Green M, Bommer GT, Cho KR, Fearon ER.

Am J Pathol. 2013 Aug;183(2):493-503. doi: 10.1016/j.ajpath.2013.04.013.

20.

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