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Items: 1 to 20 of 157

1.

A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.

Weiss RB, Baker TB, Cannon DS, von Niederhausern A, Dunn DM, Matsunami N, Singh NA, Baird L, Coon H, McMahon WM, Piper ME, Fiore MC, Scholand MB, Connett JE, Kanner RE, Gahring LC, Rogers SW, Hoidal JR, Leppert MF.

PLoS Genet. 2008 Jul 11;4(7):e1000125. doi: 10.1371/journal.pgen.1000125.

2.

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes.

Baker TB, Weiss RB, Bolt D, von Niederhausern A, Fiore MC, Dunn DM, Piper ME, Matsunami N, Smith SS, Coon H, McMahon WM, Scholand MB, Singh N, Hoidal JR, Kim SY, Leppert MF, Cannon DS.

Nicotine Tob Res. 2009 Jul;11(7):785-96. doi: 10.1093/ntr/ntp064. Epub 2009 May 12.

3.

Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans.

Li MD, Xu Q, Lou XY, Payne TJ, Niu T, Ma JZ.

Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 5;153B(3):745-56. doi: 10.1002/ajmg.b.31043.

4.

Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans.

Olfson E, Saccone NL, Johnson EO, Chen LS, Culverhouse R, Doheny K, Foltz SM, Fox L, Gogarten SM, Hartz S, Hetrick K, Laurie CC, Marosy B, Amin N, Arnett D, Barr RG, Bartz TM, Bertelsen S, Borecki IB, Brown MR, Chasman DI, van Duijn CM, Feitosa MF, Fox ER, Franceschini N, Franco OH, Grove ML, Guo X, Hofman A, Kardia SL, Morrison AC, Musani SK, Psaty BM, Rao DC, Reiner AP, Rice K, Ridker PM, Rose LM, Schick UM, Schwander K, Uitterlinden AG, Vojinovic D, Wang JC, Ware EB, Wilson G, Yao J, Zhao W, Breslau N, Hatsukami D, Stitzel JA, Rice J, Goate A, Bierut LJ.

Mol Psychiatry. 2016 May;21(5):601-7. doi: 10.1038/mp.2015.105. Epub 2015 Aug 4.

5.

Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking.

Tyndale RF, Zhu AZ, George TP, Cinciripini P, Hawk LW Jr, Schnoll RA, Swan GE, Benowitz NL, Heitjan DF, Lerman C; PGRN-PNAT Research Group.

PLoS One. 2015 May 26;10(5):e0128109. doi: 10.1371/journal.pone.0128109. eCollection 2015.

6.

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.

Saccone NL, Wang JC, Breslau N, Johnson EO, Hatsukami D, Saccone SF, Grucza RA, Sun L, Duan W, Budde J, Culverhouse RC, Fox L, Hinrichs AL, Steinbach JH, Wu M, Rice JP, Goate AM, Bierut LJ.

Cancer Res. 2009 Sep 1;69(17):6848-56. doi: 10.1158/0008-5472.CAN-09-0786. Epub 2009 Aug 25.

7.

A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence.

Hancock DB, Wang JC, Gaddis NC, Levy JL, Saccone NL, Stitzel JA, Goate A, Bierut LJ, Johnson EO.

Hum Mol Genet. 2015 Oct 15;24(20):5940-54. doi: 10.1093/hmg/ddv303. Epub 2015 Jul 28.

8.

Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes.

Chen LS, Xian H, Grucza RA, Saccone NL, Wang JC, Johnson EO, Breslau N, Hatsukami D, Bierut LJ.

Drug Alcohol Depend. 2012 Jun;123 Suppl 1:S42-51. doi: 10.1016/j.drugalcdep.2012.01.014. Epub 2012 Feb 13.

9.

Contribution of Variants in CHRNA5/A3/B4 Gene Cluster on Chromosome 15 to Tobacco Smoking: From Genetic Association to Mechanism.

Wen L, Jiang K, Yuan W, Cui W, Li MD.

Mol Neurobiol. 2016 Jan;53(1):472-484. doi: 10.1007/s12035-014-8997-x. Epub 2014 Dec 5. Review.

PMID:
25471942
11.

CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users.

Zhu AZ, Renner CC, Hatsukami DK, Benowitz NL, Tyndale RF.

Addiction. 2013 Oct;108(10):1818-28. doi: 10.1111/add.12250. Epub 2013 Jul 5.

12.

An association study on the CHRNA5/A3/B4 gene cluster, smoking and psoriasis vulgaris.

Zhu KJ, Liu Z, Liu H, Li SJ, Zhu CY, Li KS, Fan YM.

Arch Dermatol Res. 2014 Dec;306(10):939-44. doi: 10.1007/s00403-014-1510-6. Epub 2014 Oct 9.

PMID:
25297392
13.

The CHRNA5-A3-B4 gene cluster in nicotine addiction.

Berrettini WH, Doyle GA.

Mol Psychiatry. 2012 Sep;17(9):856-66. doi: 10.1038/mp.2011.122. Epub 2011 Oct 4. Review.

PMID:
21968931
14.

Markers in the 15q24 nicotinic receptor subunit gene cluster (CHRNA5-A3-B4) predict severity of nicotine addiction and response to smoking cessation therapy.

Sarginson JE, Killen JD, Lazzeroni LC, Fortmann SP, Ryan HS, Schatzberg AF, Murphy GM Jr.

Am J Med Genet B Neuropsychiatr Genet. 2011 Apr;156B(3):275-84. doi: 10.1002/ajmg.b.31155. Epub 2011 Jan 25.

PMID:
21268243
15.

Nicotine dependence in an isolated population of Kashubians from North Poland: a population survey.

Sieminska A, Jassem E, Kita-Milczarska K.

BMC Public Health. 2015 Feb 4;15:80. doi: 10.1186/s12889-015-1455-5.

16.

The polymorphism of the CHRNA5 gene and the strength of nicotine addiction in lung cancer and COPD patients.

Wojas-Krawczyk K, Krawczyk P, Biernacka B, Grzybek M, KoƂodziej P, Kucharczyk T, Mlak R, Milanowski J.

Eur J Cancer Prev. 2012 Mar;21(2):111-7. doi: 10.1097/CEJ.0b013e32834c9b40.

PMID:
21955800
17.

Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk.

Wassenaar CA, Dong Q, Wei Q, Amos CI, Spitz MR, Tyndale RF.

J Natl Cancer Inst. 2011 Sep 7;103(17):1342-6. doi: 10.1093/jnci/djr237. Epub 2011 Jul 11.

18.

Association of CHRNA5-A3-B4 variation with esophageal squamous cell carcinoma risk and smoking behaviors in a Chinese population.

Wang Y, Wu H, Liu Q, Wang C, Fu L, Wang H, Zhu W, Fu W, Lv Y, Wang S, Hu L.

PLoS One. 2013 Jul 2;8(7):e67664. doi: 10.1371/journal.pone.0067664. Print 2013.

19.

Beyond cigarettes per day. A genome-wide association study of the biomarker carbon monoxide.

Bloom AJ, Hartz SM, Baker TB, Chen LS, Piper ME, Fox L, Martinez M, Hatsukami D, Johnson EO, Laurie CC, Saccone NL, Goate A, Bierut LJ.

Ann Am Thorac Soc. 2014 Sep;11(7):1003-10. doi: 10.1513/AnnalsATS.201401-010OC.

20.

Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.

Li MD, Yoon D, Lee JY, Han BG, Niu T, Payne TJ, Ma JZ, Park T.

PLoS One. 2010 Aug 16;5(8):e12183. doi: 10.1371/journal.pone.0012183.

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