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Items: 1 to 20 of 306


Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery.

Macůrek L, Lindqvist A, Lim D, Lampson MA, Klompmaker R, Freire R, Clouin C, Taylor SS, Yaffe MB, Medema RH.

Nature. 2008 Sep 4;455(7209):119-23. doi: 10.1038/nature07185. Epub 2008 Jul 9.


Bora and Aurora-A continue to activate Plk1 in mitosis.

Bruinsma W, Macurek L, Freire R, Lindqvist A, Medema RH.

J Cell Sci. 2014 Feb 15;127(Pt 4):801-11. doi: 10.1242/jcs.137216. Epub 2013 Dec 11.


Purification and proteomic identification of putative upstream regulators of polo-like kinase-1 from mitotic cell extracts.

Ji JH, Hwang HI, Lee HJ, Hyun SY, Kang HJ, Jang YJ.

FEBS Lett. 2010 Oct 22;584(20):4299-305. doi: 10.1016/j.febslet.2010.09.025. Epub 2010 Sep 25.


Integrated computational model of cell cycle and checkpoint reveals different essential roles of Aurora-A and Plk1 in mitotic entry.

Zou J, Luo SD, Wei YQ, Yang SY.

Mol Biosyst. 2011 Jan;7(1):169-79. doi: 10.1039/c0mb00004c. Epub 2010 Oct 26.


Regulation of Polo-like kinase 1 by DNA damage in mitosis. Inhibition of mitotic PLK-1 by protein phosphatase 2A.

Jang YJ, Ji JH, Choi YC, Ryu CJ, Ko SY.

J Biol Chem. 2007 Jan 26;282(4):2473-82. Epub 2006 Nov 22.


Cdk1 activity is required for mitotic activation of aurora A during G2/M transition of human cells.

Van Horn RD, Chu S, Fan L, Yin T, Du J, Beckmann R, Mader M, Zhu G, Toth J, Blanchard K, Ye XS.

J Biol Chem. 2010 Jul 9;285(28):21849-57. doi: 10.1074/jbc.M110.141010. Epub 2010 May 5.


Kicking off the polo game.

Eckerdt F, Maller JL.

Trends Biochem Sci. 2008 Nov;33(11):511-3. doi: 10.1016/j.tibs.2008.08.004. Epub 2008 Sep 23.


Plk1-dependent phosphorylation regulates functions of DNA topoisomerase IIalpha in cell cycle progression.

Li H, Wang Y, Liu X.

J Biol Chem. 2008 Mar 7;283(10):6209-21. doi: 10.1074/jbc.M709007200. Epub 2008 Jan 2.


Furry protein promotes aurora A-mediated Polo-like kinase 1 activation.

Ikeda M, Chiba S, Ohashi K, Mizuno K.

J Biol Chem. 2012 Aug 10;287(33):27670-81. doi: 10.1074/jbc.M112.378968. Epub 2012 Jun 29.


Polo-like kinase 1 regulates mitotic arrest after UV irradiation through dephosphorylation of p53 and inducing p53 degradation.

Chen J, Dai G, Wang YQ, Wang S, Pan FY, Xue B, Zhao DH, Li CJ.

FEBS Lett. 2006 Jun 26;580(15):3624-30. Epub 2006 May 30.


Mitotic entry: The interplay between Cdk1, Plk1 and Bora.

Parrilla A, Cirillo L, Thomas Y, Gotta M, Pintard L, Santamaria A.

Cell Cycle. 2016 Dec;15(23):3177-3182. Epub 2016 Nov 10.


Polo-like kinase 1 inactivation following mitotic DNA damaging treatments is independent of ataxia telangiectasia mutated kinase.

Yuan JH, Feng Y, Fisher RH, Maloid S, Longo DL, Ferris DK.

Mol Cancer Res. 2004 Jul;2(7):417-26.


Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora.

Bruinsma W, Aprelia M, García-Santisteban I, Kool J, Xu YJ, Medema RH.

Oncogene. 2017 Mar 30;36(13):1840-1848. doi: 10.1038/onc.2016.347. Epub 2016 Oct 10.


Polo-like kinase-activating kinases: Aurora A, Aurora B and what else?

Archambault V, Carmena M.

Cell Cycle. 2012 Apr 15;11(8):1490-5. doi: 10.4161/cc.19724. Epub 2012 Apr 15.


Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis.

Yamaguchi T, Goto H, Yokoyama T, Silljé H, Hanisch A, Uldschmid A, Takai Y, Oguri T, Nigg EA, Inagaki M.

J Cell Biol. 2005 Nov 7;171(3):431-6. Epub 2005 Oct 31.


Getting in and out of mitosis with Polo-like kinase-1.

van Vugt MA, Medema RH.

Oncogene. 2005 Apr 18;24(17):2844-59. Review.


P21-activated kinase is required for mitotic progression and regulates Plk1.

Maroto B, Ye MB, von Lohneysen K, Schnelzer A, Knaus UG.

Oncogene. 2008 Aug 21;27(36):4900-8. doi: 10.1038/onc.2008.131. Epub 2008 Apr 21.


Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage.

Tsvetkov L, Stern DF.

Cell Cycle. 2005 Jan;4(1):166-71. Epub 2005 Jan 5.


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