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Items: 1 to 20 of 159

1.

G protein-independent cell-based assays for drug discovery on seven-transmembrane receptors.

Verkaar F, van Rosmalen JW, Blomenröhr M, van Koppen CJ, Blankesteijn WM, Smits JF, Zaman GJ.

Biotechnol Annu Rev. 2008;14:253-74. doi: 10.1016/S1387-2656(08)00010-0. Review.

PMID:
18606367
2.

beta-Arrestin recruitment assay for the identification of agonists of the sphingosine 1-phosphate receptor EDG1.

van Der Lee MM, Bras M, van Koppen CJ, Zaman GJ.

J Biomol Screen. 2008 Dec;13(10):986-98. doi: 10.1177/1087057108326144. Epub 2008 Nov 25.

PMID:
19036707
3.

The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.

Tohgo A, Choy EW, Gesty-Palmer D, Pierce KL, Laporte S, Oakley RH, Caron MG, Lefkowitz RJ, Luttrell LM.

J Biol Chem. 2003 Feb 21;278(8):6258-67. Epub 2002 Dec 6.

4.

Use of the BRET 7TM receptor/beta-arrestin assay in drug discovery and screening.

Heding A.

Expert Rev Mol Diagn. 2004 May;4(3):403-11.

PMID:
15137906
5.

Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2.

Hamdan FF, Rochdi MD, Breton B, Fessart D, Michaud DE, Charest PG, Laporte SA, Bouvier M.

J Biol Chem. 2007 Oct 5;282(40):29089-100. Epub 2007 Aug 3.

6.

The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS).

Bertrand L, Parent S, Caron M, Legault M, Joly E, Angers S, Bouvier M, Brown M, Houle B, Ménard L.

J Recept Signal Transduct Res. 2002 Feb-Nov;22(1-4):533-41.

PMID:
12503639
7.

Pharmacological characterization of receptor redistribution and beta-arrestin recruitment assays for the cannabinoid receptor 1.

van der Lee MM, Blomenröhr M, van der Doelen AA, Wat JW, Smits N, Hanson BJ, van Koppen CJ, Zaman GJ.

J Biomol Screen. 2009 Aug;14(7):811-23. doi: 10.1177/1087057109337937. Epub 2009 Jun 11.

PMID:
19520790
8.

beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin.

Laporte SA, Miller WE, Kim KM, Caron MG.

J Biol Chem. 2002 Mar 15;277(11):9247-54. Epub 2002 Jan 2.

9.

β-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulation.

Seitz K, Dürsch V, Harnoš J, Bryja V, Gentzel M, Schambony A.

PLoS One. 2014 Jan 29;9(1):e87132. doi: 10.1371/journal.pone.0087132. eCollection 2014.

10.

A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation.

Barak LS, Ferguson SS, Zhang J, Caron MG.

J Biol Chem. 1997 Oct 31;272(44):27497-500.

12.

Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4.

Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE, Caron MG, Barak LS, Nusse R, Lefkowitz RJ.

Science. 2003 Sep 5;301(5638):1391-4.

13.

Selective recruitment of arrestin-3 to clathrin coated pits upon stimulation of G protein-coupled receptors.

Santini F, Penn RB, Gagnon AW, Benovic JL, Keen JH.

J Cell Sci. 2000 Jul;113 ( Pt 13):2463-70.

14.

beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor.

Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, Reiter E, Premont RT, Lichtarge O, Lefkowitz RJ.

J Biol Chem. 2006 Jan 13;281(2):1261-73. Epub 2005 Nov 9.

15.
16.

Cell signaling. beta-arrestin--not just for G protein-coupled receptors.

Spiegel A.

Science. 2003 Sep 5;301(5638):1338-9. No abstract available.

PMID:
12958351
18.

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors.

Azzi M, Charest PG, Angers S, Rousseau G, Kohout T, Bouvier M, Piñeyro G.

Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11406-11. Epub 2003 Sep 17.

20.

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