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Items: 1 to 20 of 103


Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate.

Traka M, Gasper AV, Melchini A, Bacon JR, Needs PW, Frost V, Chantry A, Jones AM, Ortori CA, Barrett DA, Ball RY, Mills RD, Mithen RF.

PLoS One. 2008 Jul 2;3(7):e2568. doi: 10.1371/journal.pone.0002568.


Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli.

Gasper AV, Al-Janobi A, Smith JA, Bacon JR, Fortun P, Atherton C, Taylor MA, Hawkey CJ, Barrett DA, Mithen RF.

Am J Clin Nutr. 2005 Dec;82(6):1283-91. Erratum in: Am J Clin Nutr. 2006 Mar;83(3):724.


Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently.

Lippmann D, Lehmann C, Florian S, Barknowitz G, Haack M, Mewis I, Wiesner M, Schreiner M, Glatt H, Brigelius-Flohé R, Kipp AP.

Food Funct. 2014 Jun;5(6):1073-81. doi: 10.1039/c3fo60676g. Epub 2014 Apr 9.


Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas.

Lin HJ, Probst-Hensch NM, Louie AD, Kau IH, Witte JS, Ingles SA, Frankl HD, Lee ER, Haile RW.

Cancer Epidemiol Biomarkers Prev. 1998 Aug;7(8):647-52.


A diet rich in high-glucoraphanin broccoli interacts with genotype to reduce discordance in plasma metabolite profiles by modulating mitochondrial function.

Armah CN, Traka MH, Dainty JR, Defernez M, Janssens A, Leung W, Doleman JF, Potter JF, Mithen RF.

Am J Clin Nutr. 2013 Sep;98(3):712-22. doi: 10.3945/ajcn.113.065235.


Cruciferous vegetables, genetic polymorphisms in glutathione S-transferases M1 and T1, and prostate cancer risk.

Joseph MA, Moysich KB, Freudenheim JL, Shields PG, Bowman ED, Zhang Y, Marshall JR, Ambrosone CB.

Nutr Cancer. 2004;50(2):206-13.


A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer.

Alumkal JJ, Slottke R, Schwartzman J, Cherala G, Munar M, Graff JN, Beer TM, Ryan CW, Koop DR, Gibbs A, Gao L, Flamiatos JF, Tucker E, Kleinschmidt R, Mori M.

Invest New Drugs. 2015 Apr;33(2):480-9. doi: 10.1007/s10637-014-0189-z. Epub 2014 Nov 29.


Cruciferous vegetables have variable effects on biomarkers of systemic inflammation in a randomized controlled trial in healthy young adults.

Navarro SL, Schwarz Y, Song X, Wang CY, Chen C, Trudo SP, Kristal AR, Kratz M, Eaton DL, Lampe JW.

J Nutr. 2014 Nov;144(11):1850-7. doi: 10.3945/jn.114.197434. Epub 2014 Aug 27.


The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer.

Traka MH, Spinks CA, Doleman JF, Melchini A, Ball RY, Mills RD, Mithen RF.

Mol Cancer. 2010 Jul 13;9:189. doi: 10.1186/1476-4598-9-189.


Potent induction of phase 2 enzymes in human prostate cells by sulforaphane.

Brooks JD, Paton VG, Vidanes G.

Cancer Epidemiol Biomarkers Prev. 2001 Sep;10(9):949-54.


Dietary intake of Cruciferous vegetables, Glutathione S-transferase (GST) polymorphisms and lung cancer risk in a Caucasian population.

Wang LI, Giovannucci EL, Hunter D, Neuberg D, Su L, Christiani DC.

Cancer Causes Control. 2004 Dec;15(10):977-85.


Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: Evidence from randomised controlled trials.

Armah CN, Derdemezis C, Traka MH, Dainty JR, Doleman JF, Saha S, Leung W, Potter JF, Lovegrove JA, Mithen RF.

Mol Nutr Food Res. 2015 May;59(5):918-26. doi: 10.1002/mnfr.201400863. Epub 2015 Apr 7.


Metabolism of isothiocyanates in individuals with positive and null GSTT1 and M1 genotypes after drinking watercress juice.

Dyba M, Wang A, Noone AM, Goerlitz D, Shields P, Zheng YL, Rivlin R, Chung FL.

Clin Nutr. 2010 Dec;29(6):813-8. doi: 10.1016/j.clnu.2010.06.010. Epub 2010 Jul 24.


Absence of the glutathione S-transferase M1 gene increases cytochrome P4501A2 activity among frequent consumers of cruciferous vegetables in a Caucasian population.

Probst-Hensch NM, Tannenbaum SR, Chan KK, Coetzee GA, Ross RK, Yu MC.

Cancer Epidemiol Biomarkers Prev. 1998 Jul;7(7):635-8.


Modulation of human serum glutathione S-transferase A1/2 concentration by cruciferous vegetables in a controlled feeding study is influenced by GSTM1 and GSTT1 genotypes.

Navarro SL, Chang JL, Peterson S, Chen C, King IB, Schwarz Y, Li SS, Li L, Potter JD, Lampe JW.

Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2974-8. doi: 10.1158/1055-9965.EPI-09-0701.


Cruciferous vegetable supplementation in a controlled diet study alters the serum peptidome in a GSTM1-genotype dependent manner.

Brauer HA, Libby TE, Mitchell BL, Li L, Chen C, Randolph TW, Yasui YY, Lampe JW, Lampe PD.

Nutr J. 2011 Jan 27;10:11. doi: 10.1186/1475-2891-10-11.

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