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Items: 1 to 20 of 112


Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae.

Teske B, Taramino S, Bhuiyan MS, Kumaraswami NS, Randall SK, Barbuch R, Eckstein J, Balliano G, Bard M.

Biochim Biophys Acta. 2008 Aug;1781(8):359-66. doi: 10.1016/j.bbalip.2008.04.017. Epub 2008 May 15.


In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity.

Mo C, Milla P, Athenstaedt K, Ott R, Balliano G, Daum G, Bard M.

Biochim Biophys Acta. 2003 Jul 4;1633(1):68-74.


Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from the downstream 3-ketoreductase (Erg27) in the yeast ergosterol biosynthetic pathway.

Layer JV, Barnes BM, Yamasaki Y, Barbuch R, Li L, Taramino S, Balliano G, Bard M.

Biochim Biophys Acta. 2013 Feb;1831(2):361-9. doi: 10.1016/j.bbalip.2012.09.012. Epub 2012 Sep 27.


Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast.

Taramino S, Valachovic M, Oliaro-Bosso S, Viola F, Teske B, Bard M, Balliano G.

Biochim Biophys Acta. 2010 Feb;1801(2):156-62. doi: 10.1016/j.bbalip.2009.10.005. Epub 2009 Oct 29.


Isolation, characterization, and regulation of the Candida albicans ERG27 gene encoding the sterol 3-keto reductase.

Pierson CA, Jia N, Mo C, Lees ND, Sturm AM, Eckstein J, Barbuct R, Bard M.

Med Mycol. 2004 Oct;42(5):461-73.


Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts.

Taramino S, Teske B, Oliaro-Bosso S, Bard M, Balliano G.

Biochim Biophys Acta. 2010 Nov;1801(11):1232-7. doi: 10.1016/j.bbalip.2010.07.006. Epub 2010 Jul 24.


Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis.

Mo C, Valachovic M, Randall SK, Nickels JT, Bard M.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9739-44. Epub 2002 Jul 15.


A novel gene conserved from yeast to humans is involved in sterol biosynthesis.

Gachotte D, Eckstein J, Barbuch R, Hughes T, Roberts C, Bard M.

J Lipid Res. 2001 Jan;42(1):150-4.


Functional characterization and localization of Pneumocystis carinii lanosterol synthase.

Joffrion TM, Collins MS, Sesterhenn T, Cushion MT.

Eukaryot Cell. 2010 Jan;9(1):107-15. doi: 10.1128/EC.00264-09. Epub 2009 Nov 6.


Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles.

Milla P, Athenstaedt K, Viola F, Oliaro-Bosso S, Kohlwein SD, Daum G, Balliano G.

J Biol Chem. 2002 Jan 25;277(4):2406-12. Epub 2001 Nov 12.


Targeting of proteins involved in sterol biosynthesis to lipid particles of the yeast Saccharomyces cerevisiae.

Müllner H, Zweytick D, Leber R, Turnowsky F, Daum G.

Biochim Biophys Acta. 2004 May 27;1663(1-2):9-13.


Characterization of the Saccharomyces cerevisiae ERG27 gene encoding the 3-keto reductase involved in C-4 sterol demethylation.

Gachotte D, Sen SE, Eckstein J, Barbuch R, Krieger M, Ray BD, Bard M.

Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12655-60.


Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p.

Ott RG, Athenstaedt K, Hrastnik C, Leitner E, Bergler H, Daum G.

Biochim Biophys Acta. 2005 Jul 15;1735(2):111-8.


Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae.

Zweytick D, Leitner E, Kohlwein SD, Yu C, Rothblatt J, Daum G.

Eur J Biochem. 2000 Feb;267(4):1075-82.


Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae--a review.

Lees ND, Skaggs B, Kirsch DR, Bard M.

Lipids. 1995 Mar;30(3):221-6. Review.


4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in the ERG27 Gene Encoding 3-Ketosteroid Reductase.

Ferrante T, Barge A, Taramino S, Oliaro-Bosso S, Balliano G.

Lipids. 2016 Sep;51(9):1103-13. doi: 10.1007/s11745-016-4173-6. Epub 2016 Jul 15.


A systematic study of yeast sterol biosynthetic protein-protein interactions using the split-ubiquitin system.

Mo C, Bard M.

Biochim Biophys Acta. 2005 Dec 15;1737(2-3):152-60. Epub 2005 Nov 14.


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