Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 103


The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer.

Spolski R, Leonard WJ.

Curr Opin Immunol. 2008 Jun;20(3):295-301. doi: 10.1016/j.coi.2008.02.004. Epub 2008 Jun 12. Review.


Interleukin-21: basic biology and implications for cancer and autoimmunity.

Spolski R, Leonard WJ.

Annu Rev Immunol. 2008;26:57-79. Review.


IL-21: roles in immunopathology and cancer therapy.

Søndergaard H, Skak K.

Tissue Antigens. 2009 Dec;74(6):467-79. doi: 10.1111/j.1399-0039.2009.01382.x. Epub 2009 Oct 21. Review.


The role of interleukin-21 in HIV infection.

Pallikkuth S, Parmigiani A, Pahwa S.

Cytokine Growth Factor Rev. 2012 Aug-Oct;23(4-5):173-80. doi: 10.1016/j.cytogfr.2012.05.004. Epub 2012 Jul 2. Review.


Il-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel disease.

Liu Z, Yang L, Cui Y, Wang X, Guo C, Huang Z, Kan Q, Liu Z, Liu Y.

Inflamm Bowel Dis. 2009 Aug;15(8):1133-44. doi: 10.1002/ibd.20923.


IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice.

Rankin AL, Guay H, Herber D, Bertino SA, Duzanski TA, Carrier Y, Keegan S, Senices M, Stedman N, Ryan M, Bloom L, Medley Q, Collins M, Nickerson-Nutter C, Craft J, Young D, Dunussi-Joannopoulos K.

J Immunol. 2012 Feb 15;188(4):1656-67. doi: 10.4049/jimmunol.1003871. Epub 2012 Jan 9.


Interleukin 21: a cytokine/cytokine receptor system that has come of age.

Leonard WJ, Zeng R, Spolski R.

J Leukoc Biol. 2008 Aug;84(2):348-56. doi: 10.1189/jlb.0308149. Epub 2008 May 8. Review.


IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production.

Coquet JM, Kyparissoudis K, Pellicci DG, Besra G, Berzins SP, Smyth MJ, Godfrey DI.

J Immunol. 2007 Mar 1;178(5):2827-34.


Key role for IL-21 in experimental autoimmune uveitis.

Wang L, Yu CR, Kim HP, Liao W, Telford WG, Egwuagu CE, Leonard WJ.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9542-7. doi: 10.1073/pnas.1018182108. Epub 2011 May 18.


IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo.

Sonderegger I, Kisielow J, Meier R, King C, Kopf M.

Eur J Immunol. 2008 Jul;38(7):1833-8. doi: 10.1002/eji.200838511.


T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17.

Rangachari M, Mauermann N, Marty RR, Dirnhofer S, Kurrer MO, Komnenovic V, Penninger JM, Eriksson U.

J Exp Med. 2006 Aug 7;203(8):2009-19. Epub 2006 Jul 31.


IL-21 is a double-edged sword in the systemic lupus erythematosus-like disease of BXSB.Yaa mice.

McPhee CG, Bubier JA, Sproule TJ, Park G, Steinbuck MP, Schott WH, Christianson GJ, Morse HC 3rd, Roopenian DC.

J Immunol. 2013 Nov 1;191(9):4581-8. doi: 10.4049/jimmunol.1300439. Epub 2013 Sep 27.


Interleukin-21: a new modulator of immunity, infection, and cancer.

Brandt K, Singh PB, Bulfone-Paus S, Rückert R.

Cytokine Growth Factor Rev. 2007 Jun-Aug;18(3-4):223-32. Epub 2007 May 16. Review.


Interleukin-21-producing c-Maf-expressing CD4+ T cells induce effector CD8+ T cells and enhance autoimmune inflammation in scurfy mice.

Iwamoto T, Suto A, Tanaka S, Takatori H, Suzuki K, Iwamoto I, Nakajima H.

Arthritis Rheumatol. 2014 Aug;66(8):2079-90. doi: 10.1002/art.38658.


A critical role for IL-21 in regulating immunoglobulin production.

Ozaki K, Spolski R, Feng CG, Qi CF, Cheng J, Sher A, Morse HC 3rd, Liu C, Schwartzberg PL, Leonard WJ.

Science. 2002 Nov 22;298(5598):1630-4.


IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms.

Nguyen V, Luzina I, Rus H, Tegla C, Chen C, Rus V.

J Immunol. 2012 Jul 15;189(2):1081-93. doi: 10.4049/jimmunol.1200318. Epub 2012 Jun 20.


Human alpha beta T-cell receptor CD4-CD8 T-cell clones are predominantly Th0-like.

Katsikis PD, Cohen SB, Murison JG, Uren J, Hibbart LM, Callard RE, Di Padova F, Feldmann M, Londei M.

Immunology. 1995 Apr;84(4):501-4.


Role of interleukin-21 in inflammation and allergy.

Fina D, Fantini MC, Pallone F, Monteleone G.

Inflamm Allergy Drug Targets. 2007 Mar;6(1):63-8. Review.


IL-33/ST2 axis in inflammation and immunopathology.

Milovanovic M, Volarevic V, Radosavljevic G, Jovanovic I, Pejnovic N, Arsenijevic N, Lukic ML.

Immunol Res. 2012 Apr;52(1-2):89-99. doi: 10.1007/s12026-012-8283-9. Review.


Supplemental Content

Support Center