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Items: 1 to 20 of 100

1.

Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.

Volvert ML, Seyen S, Piette M, Evrard B, Gangolf M, Plumier JC, Bettendorff L.

BMC Pharmacol. 2008 Jun 12;8:10. doi: 10.1186/1471-2210-8-10.

2.

The multifaceted therapeutic potential of benfotiamine.

Balakumar P, Rohilla A, Krishan P, Solairaj P, Thangathirupathi A.

Pharmacol Res. 2010 Jun;61(6):482-8. doi: 10.1016/j.phrs.2010.02.008. Epub 2010 Feb 25. Review.

PMID:
20188835
3.
4.

Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice.

Pan X, Gong N, Zhao J, Yu Z, Gu F, Chen J, Sun X, Zhao L, Yu M, Xu Z, Dong W, Qin Y, Fei G, Zhong C, Xu TL.

Brain. 2010 May;133(Pt 5):1342-51. doi: 10.1093/brain/awq069. Epub 2010 Apr 12.

PMID:
20385653
5.

Pharmacokinetics of thiamine derivatives especially of benfotiamine.

Loew D.

Int J Clin Pharmacol Ther. 1996 Feb;34(2):47-50. Review.

PMID:
8929745
6.

Pharmacokinetic study of benfotiamine and the bioavailability assessment compared to thiamine hydrochloride.

Xie F, Cheng Z, Li S, Liu X, Guo X, Yu P, Gu Z.

J Clin Pharmacol. 2014 Jun;54(6):688-95. doi: 10.1002/jcph.261. Epub 2014 Jan 22.

PMID:
24399744
7.

Pharmacokinetics of the transdermal delivery of benfotiamine.

Zhu Z, Varadi G, Carter SG.

Acta Diabetol. 2016 Apr;53(2):317-22. doi: 10.1007/s00592-015-0776-2. Epub 2015 Jul 4.

PMID:
26141141
8.

Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose.

Berrone E, Beltramo E, Solimine C, Ape AU, Porta M.

J Biol Chem. 2006 Apr 7;281(14):9307-13. Epub 2006 Feb 1.

9.

Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats.

Stracke H, Hammes HP, Werkmann D, Mavrakis K, Bitsch I, Netzel M, Geyer J, Köpcke W, Sauerland C, Bretzel RG, Federlin KF.

Exp Clin Endocrinol Diabetes. 2001;109(6):330-6.

PMID:
11571671
10.

Benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage in vitro.

Schmid U, Stopper H, Heidland A, Schupp N.

Diabetes Metab Res Rev. 2008 Jul-Aug;24(5):371-7. doi: 10.1002/dmrr.860.

PMID:
18384109
11.

Thiamine and benfotiamine improve cognition and ameliorate GSK-3β-associated stress-induced behaviours in mice.

Markova N, Bazhenova N, Anthony DC, Vignisse J, Svistunov A, Lesch KP, Bettendorff L, Strekalova T.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Apr 3;75:148-156. doi: 10.1016/j.pnpbp.2016.11.001. Epub 2016 Nov 5.

PMID:
27825907
12.

Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels.

Vignisse J, Sambon M, Gorlova A, Pavlov D, Caron N, Malgrange B, Shevtsova E, Svistunov A, Anthony DC, Markova N, Bazhenova N, Coumans B, Lakaye B, Wins P, Strekalova T, Bettendorff L.

Mol Cell Neurosci. 2017 Jul;82:126-136. doi: 10.1016/j.mcn.2017.05.005. Epub 2017 May 12.

PMID:
28506637
13.

Liver, plasma and erythrocyte levels of thiamine and its phosphate esters in rats with acute ethanol intoxication: a comparison of thiamine and benfotiamine administration.

Portari GV, Vannucchi H, Jordao AA Jr.

Eur J Pharm Sci. 2013 Mar 12;48(4-5):799-802. doi: 10.1016/j.ejps.2013.01.010. Epub 2013 Jan 29.

PMID:
23369791
14.

Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine.

Hurt JK, Coleman JL, Fitzpatrick BJ, Taylor-Blake B, Bridges AS, Vihko P, Zylka MJ.

PLoS One. 2012;7(10):e48562. doi: 10.1371/journal.pone.0048562. Epub 2012 Oct 31.

15.

The compartmentation of phosphorylated thiamine derivatives in cultured neuroblastoma cells.

Bettendorff L.

Biochim Biophys Acta. 1994 May 26;1222(1):7-14.

PMID:
8186267
16.

Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose.

Pomero F, Molinar Min A, La Selva M, Allione A, Molinatti GM, Porta M.

Acta Diabetol. 2001;38(3):135-8.

PMID:
11827434
17.

Bioavailability assessment of the lipophilic benfotiamine as compared to a water-soluble thiamin derivative.

Bitsch R, Wolf M, Möller J, Heuzeroth L, Grüneklee D.

Ann Nutr Metab. 1991;35(5):292-6.

PMID:
1776825
18.

Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine.

Babaei-Jadidi R, Karachalias N, Ahmed N, Battah S, Thornalley PJ.

Diabetes. 2003 Aug;52(8):2110-20.

19.

Detection of transketolase in bone marrow-derived insulin-producing cells: benfotiamine enhances insulin synthesis and glucose metabolism.

Oh SH, Witek RP, Bae SH, Darwiche H, Jung Y, Pi L, Brown A, Petersen BE.

Stem Cells Dev. 2009 Jan-Feb;18(1):37-46. doi: 10.1089/scd.2007.0255.

20.

Paraptosis cell death induction by the thiamine analog benfotiamine in leukemia cells.

Sugimori N, Espinoza JL, Trung LQ, Takami A, Kondo Y, An DT, Sasaki M, Wakayama T, Nakao S.

PLoS One. 2015 Apr 7;10(4):e0120709. doi: 10.1371/journal.pone.0120709. eCollection 2015.

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