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Items: 1 to 20 of 137

1.

ATM protein kinase mediates full activation of Akt and regulates glucose transporter 4 translocation by insulin in muscle cells.

Halaby MJ, Hibma JC, He J, Yang DQ.

Cell Signal. 2008 Aug;20(8):1555-63. doi: 10.1016/j.cellsig.2008.04.011. Epub 2008 Apr 26.

PMID:
18534819
2.

Ataxia telangiectasia mutated impacts insulin-like growth factor 1 signalling in skeletal muscle.

Ching JK, Luebbert SH, Collins RL 4th, Zhang Z, Marupudi N, Banerjee S, Hurd RD, Ralston L, Fisher JS.

Exp Physiol. 2013 Feb;98(2):526-35. doi: 10.1113/expphysiol.2012.066357. Epub 2012 Aug 31.

3.

Functional switching of ATM: sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells.

Li Y, Xiong H, Yang DQ.

Chin J Cancer. 2012 Aug;31(8):364-72. doi: 10.5732/cjc.012.10086. Epub 2012 Jun 26.

4.

Cytoplasmic ATM protein kinase: an emerging therapeutic target for diabetes, cancer and neuronal degeneration.

Yang DQ, Halaby MJ, Li Y, Hibma JC, Burn P.

Drug Discov Today. 2011 Apr;16(7-8):332-8. doi: 10.1016/j.drudis.2011.02.001. Epub 2011 Feb 15. Review.

PMID:
21315178
5.

Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM.

Viniegra JG, Martínez N, Modirassari P, Hernández Losa J, Parada Cobo C, Sánchez-Arévalo Lobo VJ, Aceves Luquero CI, Alvarez-Vallina L, Ramón y Cajal S, Rojas JM, Sánchez-Prieto R.

J Biol Chem. 2005 Feb 11;280(6):4029-36. Epub 2004 Nov 15.

6.

The ATM inhibitor KU-55933 suppresses cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.

Li Y, Yang DQ.

Mol Cancer Ther. 2010 Jan;9(1):113-25. doi: 10.1158/1535-7163.MCT-08-1189. Epub 2010 Jan 6.

7.

Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice.

Shao J, Yamashita H, Qiao L, Friedman JE.

J Endocrinol. 2000 Oct;167(1):107-15.

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10.

Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells.

Biton S, Dar I, Mittelman L, Pereg Y, Barzilai A, Shiloh Y.

J Biol Chem. 2006 Jun 23;281(25):17482-91. Epub 2006 Apr 20.

11.

A high-fructose diet impairs Akt and PKCzeta phosphorylation and GLUT4 translocation in rat skeletal muscle.

Li P, Koike T, Qin B, Kubota M, Kawata Y, Jia YJ, Oshida Y.

Horm Metab Res. 2008 Aug;40(8):528-32. doi: 10.1055/s-2008-1073162. Epub 2008 May 21.

PMID:
18500676
12.

Astragalus polysaccharide improves insulin sensitivity in KKAy mice: regulation of PKB/GLUT4 signaling in skeletal muscle.

Liu M, Wu K, Mao X, Wu Y, Ouyang J.

J Ethnopharmacol. 2010 Jan 8;127(1):32-7. doi: 10.1016/j.jep.2009.09.055. Epub 2009 Oct 2.

PMID:
19800959
13.
14.

Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence.

Zhan H, Suzuki T, Aizawa K, Miyagawa K, Nagai R.

J Biol Chem. 2010 Sep 17;285(38):29662-70. doi: 10.1074/jbc.M110.125138. Epub 2010 Jul 16.

15.

Mechanism of improving effect of losartan on insulin sensitivity of non-insulin-dependent diabetes mellitus rats.

Wu Y, Ouyang JP, Zhou YF, Wu K, Zhao DH, Wen CY.

Sheng Li Xue Bao. 2004 Aug 25;56(4):539-49.

16.

High-fat diet feeding impairs both the expression and activity of AMPKa in rats' skeletal muscle.

Liu Y, Wan Q, Guan Q, Gao L, Zhao J.

Biochem Biophys Res Commun. 2006 Jan 13;339(2):701-7. Epub 2005 Nov 21.

PMID:
16316631
17.

Analysis of the ataxia telangiectasia mutated-mediated DNA damage response in murine cerebellar neurons.

Dar I, Biton S, Shiloh Y, Barzilai A.

J Neurosci. 2006 Jul 19;26(29):7767-74.

18.

Role of PKCzeta translocation in the development of type 2 diabetes in rats following continuous glucose infusion.

Zhang JF, Yang JP, Wang GH, Xia Z, Duan SZ, Wu Y.

Diabetes Metab Res Rev. 2010 Jan;26(1):59-70. doi: 10.1002/dmrr.1056.

19.

The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation.

Saito T, Jones CC, Huang S, Czech MP, Pilch PF.

J Biol Chem. 2007 Nov 2;282(44):32280-7. Epub 2007 Sep 11.

20.

Angiotensin II-induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells.

Wei Y, Sowers JR, Nistala R, Gong H, Uptergrove GM, Clark SE, Morris EM, Szary N, Manrique C, Stump CS.

J Biol Chem. 2006 Nov 17;281(46):35137-46. Epub 2006 Sep 17.

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