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Items: 1 to 20 of 305

1.

Abcg5/8 independent biliary cholesterol excretion in Atp8b1-deficient mice.

Groen A, Kunne C, Jongsma G, van den Oever K, Mok KS, Petruzzelli M, Vrins CL, Bull L, Paulusma CC, Oude Elferink RP.

Gastroenterology. 2008 Jun;134(7):2091-100. doi: 10.1053/j.gastro.2008.02.097. Epub 2008 Mar 8.

PMID:
18466903
2.

Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice.

Plösch T, van der Veen JN, Havinga R, Huijkman NC, Bloks VW, Kuipers F.

Am J Physiol Gastrointest Liver Physiol. 2006 Sep;291(3):G414-23. Epub 2006 Apr 13.

3.

Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice.

Kosters A, Frijters RJ, Schaap FG, Vink E, Plösch T, Ottenhoff R, Jirsa M, De Cuyper IM, Kuipers F, Groen AK.

J Hepatol. 2003 Jun;38(6):710-6.

PMID:
12763362
4.

Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.

Plösch T, Bloks VW, Terasawa Y, Berdy S, Siegler K, Van Der Sluijs F, Kema IP, Groen AK, Shan B, Kuipers F, Schwarz M.

Gastroenterology. 2004 Jan;126(1):290-300. Erratum in: Gastroenterology. 2004 Mar;126(3):944. Schwartz Margrit [corrected to Schwarz Margrit].

PMID:
14699507
5.

Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice.

Wiersma H, Gatti A, Nijstad N, Oude Elferink RP, Kuipers F, Tietge UJ.

Hepatology. 2009 Oct;50(4):1263-72. doi: 10.1002/hep.23112.

PMID:
19637290
6.

Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.

Yu L, York J, von Bergmann K, Lutjohann D, Cohen JC, Hobbs HH.

J Biol Chem. 2003 May 2;278(18):15565-70. Epub 2003 Feb 22.

7.

ABCG5/ABCG8-independent biliary cholesterol excretion in lactating rats.

Coy DJ, Wooton-Kee CR, Yan B, Sabeva N, Su K, Graf G, Vore M.

Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G228-35. doi: 10.1152/ajpgi.00502.2009. Epub 2010 Apr 22.

8.

Activity of the bile salt export pump (ABCB11) is critically dependent on canalicular membrane cholesterol content.

Paulusma CC, de Waart DR, Kunne C, Mok KS, Elferink RP.

J Biol Chem. 2009 Apr 10;284(15):9947-54. doi: 10.1074/jbc.M808667200. Epub 2009 Feb 19.

9.

Evidence that the adenosine triphosphate-binding cassette G5/G8-independent pathway plays a determinant role in cholesterol gallstone formation in mice.

Wang HH, Li X, Patel SB, Wang DQ.

Hepatology. 2016 Sep;64(3):853-64. doi: 10.1002/hep.28570. Epub 2016 Jun 3.

PMID:
27014967
10.

Hepatic ABCG5/G8 overexpression substantially increases biliary cholesterol secretion but does not impact in vivo macrophage-to-feces RCT.

Dikkers A, de Boer JF, Groen AK, Tietge UJ.

Atherosclerosis. 2015 Dec;243(2):402-6. doi: 10.1016/j.atherosclerosis.2015.10.010. Epub 2015 Oct 8.

PMID:
26520893
11.

Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR.

Khovidhunkit W, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR.

J Lipid Res. 2003 Sep;44(9):1728-36. Epub 2003 Jun 1.

12.

Hepatic expression of ABC transporters G5 and G8 does not correlate with biliary cholesterol secretion in liver transplant patients.

Geuken E, Visser DS, Leuvenink HG, de Jong KP, Peeters PM, Slooff MJ, Kuipers F, Porte RJ.

Hepatology. 2005 Nov;42(5):1166-74.

PMID:
16250035
13.

The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice.

Kosters A, Kunne C, Looije N, Patel SB, Oude Elferink RP, Groen AK.

J Lipid Res. 2006 Sep;47(9):1959-66. Epub 2006 Jun 1.

14.

Stimulation of murine biliary cholesterol secretion by thyroid hormone is dependent on a functional ABCG5/G8 complex.

Bonde Y, Plösch T, Kuipers F, Angelin B, Rudling M.

Hepatology. 2012 Nov;56(5):1828-37. doi: 10.1002/hep.25861. Epub 2012 Oct 14.

15.

Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol.

van der Veen JN, van Dijk TH, Vrins CL, van Meer H, Havinga R, Bijsterveld K, Tietge UJ, Groen AK, Kuipers F.

J Biol Chem. 2009 Jul 17;284(29):19211-9. doi: 10.1074/jbc.M109.014860. Epub 2009 May 5.

16.

A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol.

Klett EL, Lu K, Kosters A, Vink E, Lee MH, Altenburg M, Shefer S, Batta AK, Yu H, Chen J, Klein R, Looije N, Oude-Elferink R, Groen AK, Maeda N, Salen G, Patel SB.

BMC Med. 2004 Mar 24;2:5.

17.

Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol.

Heverin M, Meaney S, Brafman A, Shafir M, Olin M, Shafaati M, von Bahr S, Larsson L, Lövgren-Sandblom A, Diczfalusy U, Parini P, Feinstein E, Björkhem I.

Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2191-7. Epub 2007 Aug 30.

18.

Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport.

Paulusma CC, Groen A, Kunne C, Ho-Mok KS, Spijkerboer AL, Rudi de Waart D, Hoek FJ, Vreeling H, Hoeben KA, van Marle J, Pawlikowska L, Bull LN, Hofmann AF, Knisely AS, Oude Elferink RP.

Hepatology. 2006 Jul;44(1):195-204.

PMID:
16799980
19.

The mechanism of increased biliary lipid secretion in mice with genetic inactivation of bile salt export pump.

Gooijert KE, Havinga R, Wolters H, Wang R, Ling V, Tazuma S, Verkade HJ.

Am J Physiol Gastrointest Liver Physiol. 2015 Mar 1;308(5):G450-7. doi: 10.1152/ajpgi.00391.2014. Epub 2014 Dec 31.

20.

Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

Repa JJ, Berge KE, Pomajzl C, Richardson JA, Hobbs H, Mangelsdorf DJ.

J Biol Chem. 2002 May 24;277(21):18793-800. Epub 2002 Mar 18.

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