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Items: 1 to 20 of 109

1.

Regulatory polymorphisms and their contribution to interindividual differences in the expression of enzymes influencing drug and toxicant disposition.

Hines RN, Koukouritaki SB, Poch MT, Stephens MC.

Drug Metab Rev. 2008;40(2):263-301. doi: 10.1080/03602530801952682 . Review.

PMID:
18464046
2.

Impact of genetic polymorphisms in transmembrane carrier-systems on drug and xenobiotic distribution.

Gerloff T.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Jan;369(1):69-77. Review. Erratum in: Naunyn Schmiedebergs Arch Pharmacol. 2004 Feb;369(2):268.

PMID:
14598019
3.

Genetic polymorphisms in drug-metabolizing enzymes and drug targets.

Hiratsuka M, Mizugaki M.

Mol Genet Metab. 2001 Aug;73(4):298-305. Review. No abstract available.

PMID:
11509011
4.

Polymorphisms affecting gene regulation and mRNA processing: broad implications for pharmacogenetics.

Johnson AD, Wang D, Sadee W.

Pharmacol Ther. 2005 Apr;106(1):19-38. Review.

PMID:
15781120
5.
6.

The biochemistry of drug metabolism--an introduction: part 6. Inter-individual factors affecting drug metabolism.

Krämer SD, Testa B.

Chem Biodivers. 2008 Dec;5(12):2465-578. doi: 10.1002/cbdv.200890214. Review. Erratum in: Chem Biodivers. 2009 Jul;6(7):1144.

PMID:
19089818
7.

Genetic polymorphisms in human drug-metabolizing enzymes: potential uses of reverse genetics to identify genes of toxicological relevance.

Puga A, Nebert DW, McKinnon RA, Menon AG.

Crit Rev Toxicol. 1997 Mar;27(2):199-222. Review.

PMID:
9099519
8.

Ontogeny of drug metabolizing enzymes in the neonate.

Blake MJ, Castro L, Leeder JS, Kearns GL.

Semin Fetal Neonatal Med. 2005 Apr;10(2):123-38. Review.

PMID:
15701578
9.

Epigenetic regulation of genes encoding drug-metabolizing enzymes and transporters; DNA methylation and other mechanisms.

Hirota T, Takane H, Higuchi S, Ieiri I.

Curr Drug Metab. 2008 Jan;9(1):34-8. Review.

PMID:
18220569
10.

An overview of the relations between polymorphisms in drug metabolising enzymes and drug transporters and survival after cancer drug treatment.

Ekhart C, Rodenhuis S, Smits PH, Beijnen JH, Huitema AD.

Cancer Treat Rev. 2009 Feb;35(1):18-31. doi: 10.1016/j.ctrv.2008.07.003. Review.

PMID:
18771857
11.
12.

[Overview: molecular variation, specific tissue localization and genetic polymorphisms of drug transporters].

Sugiyama Y, Maeda K.

Nihon Yakurigaku Zasshi. 2005 Apr;125(4):178-84. Review. Japanese. No abstract available.

PMID:
15930793
13.

Biomarkers in aquatic plants: selection and utility.

Brain RA, Cedergreen N.

Rev Environ Contam Toxicol. 2009;198:49-109. doi: 10.1007/978-0-387-09647-6_2. Review.

PMID:
19253039
14.

So many studies, too few subjects: establishing functional relevance of genetic polymorphisms on pharmacokinetics.

Williams JA, Johnson K, Paulauskis J, Cook J.

J Clin Pharmacol. 2006 Mar;46(3):258-64.

PMID:
16490801
15.

Validation of the performance of a comprehensive genotyping assay panel of single nucleotide polymorphisms in drug metabolism enzyme genes.

Welch RA, Lazaruk K, Haque KA, Hyland F, Xiao N, Wronka L, Burdett L, Chanock SJ, Ingber D, De La Vega FM, Yeager M.

Hum Mutat. 2008 May;29(5):750-6. doi: 10.1002/humu.20703.

PMID:
18327779
16.

Genetically determined polymorphisms in drug oxidation.

Jacqz E, Hall SD, Branch RA.

Hepatology. 1986 Sep-Oct;6(5):1020-32. No abstract available.

PMID:
3758933
17.

The evolution of drug metabolism.

Nebert DW, Dieter MZ.

Pharmacology. 2000 Sep;61(3):124-35. Review.

PMID:
10971198
18.

Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes.

Okey AB, Boutros PC, Harper PA.

Pharmacogenet Genomics. 2005 Jun;15(6):371-9. Review.

PMID:
15900209
19.

Genetic polymorphisms of drug-metabolizing enzymes: molecular mechanisms.

Meyer UA, Zanger U, Skoda R, Grant DM.

Psychopharmacol Ser. 1989;7:141-7. Review. No abstract available.

PMID:
2687852
20.

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