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Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virus.

Sarma N, Agarwal D, Shiflett LA, Read GS.

J Virol. 2008 Jul;82(13):6600-9. doi: 10.1128/JVI.00137-08. Epub 2008 Apr 30.


The virion host shutoff endonuclease (UL41) of herpes simplex virus interacts with the cellular cap-binding complex eIF4F.

Page HG, Read GS.

J Virol. 2010 Jul;84(13):6886-90. doi: 10.1128/JVI.00166-10. Epub 2010 Apr 28.


The pseudorabies virus vhs protein cleaves RNA containing an IRES sequence.

Liu YF, Tsai PY, Chulakasian S, Lin FY, Hsu WL.

FEBS J. 2016 Mar;283(5):899-911. doi: 10.1111/febs.13642. Epub 2016 Feb 3.


The herpes simplex virus 1 virion host shutoff protein enhances translation of viral late mRNAs by preventing mRNA overload.

Dauber B, Saffran HA, Smiley JR.

J Virol. 2014 Sep 1;88(17):9624-32. doi: 10.1128/JVI.01350-14. Epub 2014 Jun 11.


Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase.

Taddeo B, Zhang W, Roizman B.

J Virol. 2010 Oct;84(19):10182-90. doi: 10.1128/JVI.00975-10. Epub 2010 Jul 14.


Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein.

Shu M, Taddeo B, Zhang W, Roizman B.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):E1669-75. doi: 10.1073/pnas.1305475110. Epub 2013 Apr 15.


The effect of herpes simplex virus virion host shutoff gene- a new suicide gene- on tumor cells.

Bannazadeh Baghi H, Bamdad T, Soleimanjahi H.

Iran Biomed J. 2009 Jul;13(3):185-9.


Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage.

Shu M, Taddeo B, Roizman B.

J Virol. 2015 May;89(10):5643-50. doi: 10.1128/JVI.00091-15. Epub 2015 Mar 11.


The Herpes Simplex Virus Virion Host Shutoff Protein Enhances Translation of Viral True Late mRNAs Independently of Suppressing Protein Kinase R and Stress Granule Formation.

Dauber B, Poon D, Dos Santos T, Duguay BA, Mehta N, Saffran HA, Smiley JR.

J Virol. 2016 Jun 10;90(13):6049-57. doi: 10.1128/JVI.03180-15. Print 2016 Jul 1.


The herpes simplex virus 1 vhs protein enhances translation of viral true late mRNAs and virus production in a cell type-dependent manner.

Dauber B, Pelletier J, Smiley JR.

J Virol. 2011 Jun;85(11):5363-73. doi: 10.1128/JVI.00115-11. Epub 2011 Mar 23.


The herpes simplex virus host shutoff RNase degrades cellular and viral mRNAs made before infection but not viral mRNA made after infection.

Taddeo B, Zhang W, Roizman B.

J Virol. 2013 Apr;87(8):4516-22. doi: 10.1128/JVI.00005-13. Epub 2013 Feb 6.

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