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Items: 1 to 20 of 159


Critical role of extracellular heat shock cognate protein 70 in the myocardial inflammatory response and cardiac dysfunction after global ischemia-reperfusion.

Zou N, Ao L, Cleveland JC Jr, Yang X, Su X, Cai GY, Banerjee A, Fullerton DA, Meng X.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2805-13. doi: 10.1152/ajpheart.00299.2008. Epub 2008 Apr 25.


Myocardial TLR4 is a determinant of neutrophil infiltration after global myocardial ischemia: mediating KC and MCP-1 expression induced by extracellular HSC70.

Ao L, Zou N, Cleveland JC Jr, Fullerton DA, Meng X.

Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H21-8. doi: 10.1152/ajpheart.00292.2009. Epub 2009 May 15.


Human myocardium releases heat shock protein 27 (HSP27) after global ischemia: the proinflammatory effect of extracellular HSP27 through toll-like receptor (TLR)-2 and TLR4.

Jin C, Cleveland JC, Ao L, Li J, Zeng Q, Fullerton DA, Meng X.

Mol Med. 2014 Jun 9;20:280-9. doi: 10.2119/molmed.2014.00058.


Cytokines link Toll-like receptor 4 signaling to cardiac dysfunction after global myocardial ischemia.

Cha J, Wang Z, Ao L, Zou N, Dinarello CA, Banerjee A, Fullerton DA, Meng X.

Ann Thorac Surg. 2008 May;85(5):1678-85. doi: 10.1016/j.athoracsur.2008.01.043.


Extracellular heat shock cognate protein 70 induces cardiac functional tolerance to endotoxin: differential effect on TNF-alpha and ICAM-1 levels in heart tissue.

Su X, Sykes JB, Ao L, Raeburn CD, Fullerton DA, Meng X.

Cytokine. 2010 Jul;51(1):60-6. doi: 10.1016/j.cyto.2010.04.014. Epub 2010 May 15.


Toll-like receptor 5 deficiency exacerbates cardiac injury and inflammation induced by myocardial ischaemia-reperfusion in the mouse.

Parapanov R, Lugrin J, Rosenblatt-Velin N, Feihl F, Waeber B, Milano G, Vergely C, Li N, Pacher P, Liaudet L.

Clin Sci (Lond). 2015 Jul;129(2):187-98. doi: 10.1042/CS20140444.


Toll-like receptor-2 mediates adaptive cardiac hypertrophy in response to pressure overload through interleukin-1β upregulation via nuclear factor κB activation.

Higashikuni Y, Tanaka K, Kato M, Nureki O, Hirata Y, Nagai R, Komuro I, Sata M.

J Am Heart Assoc. 2013 Nov 18;2(6):e000267. doi: 10.1161/JAHA.113.000267.


Toll-like receptor 4 mediates the inflammatory responses and matrix protein remodeling in remote non-ischemic myocardium in a mouse model of myocardial ischemia and reperfusion.

Zhai Y, Ao L, Cleveland JC, Zeng Q, Reece TB, Fullerton DA, Meng X.

PLoS One. 2015 Mar 30;10(3):e0121853. doi: 10.1371/journal.pone.0121853. eCollection 2015.


The HMGB1-TLR4 axis contributes to myocardial ischemia/reperfusion injury via regulation of cardiomyocyte apoptosis.

Ding HS, Yang J, Chen P, Yang J, Bo SQ, Ding JW, Yu QQ.

Gene. 2013 Sep 15;527(1):389-93. doi: 10.1016/j.gene.2013.05.041. Epub 2013 May 30.


Bacterial DNA induces myocardial inflammation and reduces cardiomyocyte contractility: role of toll-like receptor 9.

Knuefermann P, Schwederski M, Velten M, Krings P, Ehrentraut H, Rüdiger M, Boehm O, Fink K, Dreiner U, Grohé C, Hoeft A, Baumgarten G, Koch A, Zacharowski K, Meyer R.

Cardiovasc Res. 2008 Apr 1;78(1):26-35. doi: 10.1093/cvr/cvn011. Epub 2008 Jan 14.


Novel Toll-like receptor-4 deficiency attenuates trastuzumab (Herceptin) induced cardiac injury in mice.

Yousif NG, Al-Amran FG.

BMC Cardiovasc Disord. 2011 Oct 14;11:62. doi: 10.1186/1471-2261-11-62.


Sulforaphane improves oxidative status without attenuating the inflammatory response or cardiac impairment induced by ischemia-reperfusion in rats.

Bonetto JH, Fernandes RO, Seolin BG, Müller DD, Teixeira RB, Araujo AS, Vassallo D, Schenkel PC, Belló-Klein A.

Can J Physiol Pharmacol. 2016 May;94(5):508-16. doi: 10.1139/cjpp-2015-0282. Epub 2015 Nov 19.


Improved myocardial preservation with short hyperthermia prior to cold cardioplegic ischemia in immature rabbit hearts.

Vogt S, Troitzsch D, Abdul-Khaliq H, Böttcher W, Lange PE, Moosdorf R.

Eur J Cardiothorac Surg. 2000 Aug;18(2):233-40.


Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response.

Boyd JH, Mathur S, Wang Y, Bateman RM, Walley KR.

Cardiovasc Res. 2006 Dec 1;72(3):384-93. Epub 2006 Sep 23.


Embryonic stem cells attenuate myocardial dysfunction and inflammation after surgical global ischemia via paracrine actions.

Crisostomo PR, Abarbanell AM, Wang M, Lahm T, Wang Y, Meldrum DR.

Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1726-35. doi: 10.1152/ajpheart.00236.2008. Epub 2008 Aug 22.


Attenuated recovery of contractile function in aging hearts following global ischemia/reperfusion: Role of extracellular HSP27 and TLR4.

Ao L, Zhai Y, Jin C, Cleveland JC, Fullerton DA, Meng X.

Mol Med. 2016 Dec 19;23. doi: 10.2119/molmed.2016.00204. [Epub ahead of print]


κ-Opioid receptor stimulation modulates TLR4/NF-κB signaling in the rat heart subjected to ischemia-reperfusion.

Lin J, Wang H, Li J, Wang Q, Zhang S, Feng N, Fan R, Pei J.

Cytokine. 2013 Mar;61(3):842-8. doi: 10.1016/j.cyto.2013.01.002. Epub 2013 Feb 10.


Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury.

Sakata Y, Dong JW, Vallejo JG, Huang CH, Baker JS, Tracey KJ, Tacheuchi O, Akira S, Mann DL.

Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H503-9. Epub 2006 Sep 15.


Expression of SERCA isoform with faster Ca2+ transport properties improves postischemic cardiac function and Ca2+ handling and decreases myocardial infarction.

Talukder MA, Kalyanasundaram A, Zhao X, Zuo L, Bhupathy P, Babu GJ, Cardounel AJ, Periasamy M, Zweier JL.

Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2418-28. Epub 2007 Jul 13.


Toll-like receptor 3 plays a role in myocardial infarction and ischemia/reperfusion injury.

Lu C, Ren D, Wang X, Ha T, Liu L, Lee EJ, Hu J, Kalbfleisch J, Gao X, Kao R, Williams D, Li C.

Biochim Biophys Acta. 2014 Jan;1842(1):22-31. doi: 10.1016/j.bbadis.2013.10.006. Epub 2013 Oct 16.

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