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Items: 1 to 20 of 69

1.

Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1.

Hirabayashi S, Nakagawa K, Sumita K, Hidaka S, Kawai T, Ikeda M, Kawata A, Ohno K, Hata Y.

Oncogene. 2008 Jul 17;27(31):4281-92. doi: 10.1038/onc.2008.66. Epub 2008 Mar 24.

PMID:
18362890
2.

Roles of mammalian sterile 20-like kinase 2-dependent phosphorylations of Mps one binder 1B in the activation of nuclear Dbf2-related kinases.

Bao Y, Sumita K, Kudo T, Withanage K, Nakagawa K, Ikeda M, Ohno K, Wang Y, Hata Y.

Genes Cells. 2009 Dec;14(12):1369-81. doi: 10.1111/j.1365-2443.2009.01354.x. Epub 2009 Nov 16.

3.

NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis.

Vichalkovski A, Gresko E, Cornils H, Hergovich A, Schmitz D, Hemmings BA.

Curr Biol. 2008 Dec 9;18(23):1889-95. doi: 10.1016/j.cub.2008.10.060.

4.

Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases.

Devroe E, Erdjument-Bromage H, Tempst P, Silver PA.

J Biol Chem. 2004 Jun 4;279(23):24444-51. Epub 2004 Apr 2.

5.

MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes.

Chiba S, Ikeda M, Katsunuma K, Ohashi K, Mizuno K.

Curr Biol. 2009 Apr 28;19(8):675-81. doi: 10.1016/j.cub.2009.02.054. Epub 2009 Mar 26.

6.

Regulation of mammalian STE20-like kinase 2 (MST2) by protein phosphorylation/dephosphorylation and proteolysis.

Deng Y, Pang A, Wang JH.

J Biol Chem. 2003 Apr 4;278(14):11760-7. Epub 2003 Jan 27.

7.

Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation.

Xiong S, Couzens AL, Kean MJ, Mao DY, Guettler S, Kurinov I, Gingras AC, Sicheri F.

Mol Cell Proteomics. 2017 Jun;16(6):1111-1125. doi: 10.1074/mcp.M117.068130. Epub 2017 Apr 3.

PMID:
28373297
8.

Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein.

Bichsel SJ, Tamaskovic R, Stegert MR, Hemmings BA.

J Biol Chem. 2004 Aug 20;279(34):35228-35. Epub 2004 Jun 14.

9.

HIV-1 incorporates and proteolytically processes human NDR1 and NDR2 serine-threonine kinases.

Devroe E, Silver PA, Engelman A.

Virology. 2005 Jan 5;331(1):181-9.

10.

Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase.

Tamaskovic R, Bichsel SJ, Rogniaux H, Stegert MR, Hemmings BA.

J Biol Chem. 2003 Feb 28;278(9):6710-8. Epub 2002 Dec 17.

11.

Regulation of NDR2 protein kinase by multi-site phosphorylation and the S100B calcium-binding protein.

Stegert MR, Tamaskovic R, Bichsel SJ, Hergovich A, Hemmings BA.

J Biol Chem. 2004 May 28;279(22):23806-12. Epub 2004 Mar 22.

12.

The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1.

Chan EH, Nousiainen M, Chalamalasetty RB, Schäfer A, Nigg EA, Silljé HH.

Oncogene. 2005 Mar 17;24(12):2076-86.

PMID:
15688006
13.

Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3.

Stegert MR, Hergovich A, Tamaskovic R, Bichsel SJ, Hemmings BA.

Mol Cell Biol. 2005 Dec;25(24):11019-29.

14.

Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors.

Fuller SJ, Pikkarainen S, Tham el L, Cullingford TE, Molkentin JD, Cornils H, Hergovich A, Hemmings BA, Clerk A, Sugden PH.

Cell Signal. 2008 Aug;20(8):1564-77. doi: 10.1016/j.cellsig.2008.04.013. Epub 2008 May 1.

PMID:
18555663
15.

Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.

Ni L, Zheng Y, Hara M, Pan D, Luo X.

Genes Dev. 2015 Jul 1;29(13):1416-31. doi: 10.1101/gad.264929.115. Epub 2015 Jun 24.

16.

MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation.

Praskova M, Xia F, Avruch J.

Curr Biol. 2008 Mar 11;18(5):311-21. doi: 10.1016/j.cub.2008.02.006.

17.
18.

Ndr protein kinase is regulated by phosphorylation on two conserved sequence motifs.

Millward TA, Hess D, Hemmings BA.

J Biol Chem. 1999 Nov 26;274(48):33847-50.

19.

Protein kinases of the Hippo pathway: regulation and substrates.

Avruch J, Zhou D, Fitamant J, Bardeesy N, Mou F, Barrufet LR.

Semin Cell Dev Biol. 2012 Sep;23(7):770-84. doi: 10.1016/j.semcdb.2012.07.002. Epub 2012 Aug 9. Review.

20.

The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2.

Guo C, Zhang X, Pfeifer GP.

J Biol Chem. 2011 Feb 25;286(8):6253-61. doi: 10.1074/jbc.M110.178210. Epub 2011 Jan 3.

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