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Items: 1 to 20 of 87

1.

The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor.

Schlisio S, Kenchappa RS, Vredeveld LC, George RE, Stewart R, Greulich H, Shahriari K, Nguyen NV, Pigny P, Dahia PL, Pomeroy SL, Maris JM, Look AT, Meyerson M, Peeper DS, Carter BD, Kaelin WG Jr.

Genes Dev. 2008 Apr 1;22(7):884-93. doi: 10.1101/gad.1648608. Epub 2008 Mar 11.

2.

Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer.

Lee S, Nakamura E, Yang H, Wei W, Linggi MS, Sajan MP, Farese RV, Freeman RS, Carter BD, Kaelin WG Jr, Schlisio S.

Cancer Cell. 2005 Aug;8(2):155-67.

3.

RNA helicase A is a downstream mediator of KIF1Bβ tumor-suppressor function in neuroblastoma.

Chen ZX, Wallis K, Fell SM, Sobrado VR, Hemmer MC, Ramsköld D, Hellman U, Sandberg R, Kenchappa RS, Martinson T, Johnsen JI, Kogner P, Schlisio S.

Cancer Discov. 2014 Apr;4(4):434-51. doi: 10.1158/2159-8290.CD-13-0362. Epub 2014 Jan 27.

4.

KIF1Bbeta functions as a haploinsufficient tumor suppressor gene mapped to chromosome 1p36.2 by inducing apoptotic cell death.

Munirajan AK, Ando K, Mukai A, Takahashi M, Suenaga Y, Ohira M, Koda T, Hirota T, Ozaki T, Nakagawara A.

J Biol Chem. 2008 Sep 5;283(36):24426-34. doi: 10.1074/jbc.M802316200. Epub 2008 Jul 9.

5.

Genomic structure and mutational analysis of the human KIF1Balpha gene located at 1p36.2 in neuroblastoma.

Chen YY, Takita J, Chen YZ, Yang HW, Hanada R, Yamamoto K, Hayashi Y.

Int J Oncol. 2003 Sep;23(3):737-44.

PMID:
12888911
6.

The 1p36 Tumor Suppressor KIF 1Bβ Is Required for Calcineurin Activation, Controlling Mitochondrial Fission and Apoptosis.

Li S, Fell SM, Surova O, Smedler E, Wallis K, Chen ZX, Hellman U, Johnsen JI, Martinsson T, Kenchappa RS, Uhlén P, Kogner P, Schlisio S.

Dev Cell. 2016 Jan 25;36(2):164-78. doi: 10.1016/j.devcel.2015.12.029.

7.

Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.

Aprelikova O, Chandramouli GV, Wood M, Vasselli JR, Riss J, Maranchie JK, Linehan WM, Barrett JC.

J Cell Biochem. 2004 Jun 1;92(3):491-501. Erratum in: J Cell Biochem. 2004 Oct 15;93(3):639.

PMID:
15156561
8.

Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.

Fell SM, Li S, Wallis K, Kock A, Surova O, Rraklli V, Höfig CS, Li W, Mittag J, Henriksson MA, Kenchappa RS, Holmberg J, Kogner P, Schlisio S.

Genes Dev. 2017 May 15;31(10):1036-1053. doi: 10.1101/gad.297077.117.

PMID:
28637693
9.

Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility.

Astuti D, Ricketts CJ, Chowdhury R, McDonough MA, Gentle D, Kirby G, Schlisio S, Kenchappa RS, Carter BD, Kaelin WG Jr, Ratcliffe PJ, Schofield CJ, Latif F, Maher ER.

Endocr Relat Cancer. 2010 Dec 21;18(1):73-83. doi: 10.1677/ERC-10-0113. Print 2011 Feb.

10.

The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress.

Mikhaylova O, Ignacak ML, Barankiewicz TJ, Harbaugh SV, Yi Y, Maxwell PH, Schneider M, Van Geyte K, Carmeliet P, Revelo MP, Wyder M, Greis KD, Meller J, Czyzyk-Krzeska MF.

Mol Cell Biol. 2008 Apr;28(8):2701-17. doi: 10.1128/MCB.01231-07. Epub 2008 Feb 19.

11.

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].

Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ.

J Biol Chem. 2004 Oct 8;279(41):42719-25. Epub 2004 Aug 9. Erratum in: J Biol Chem. 2004 Dec 24;279(52):54974.

12.

KIF1Bβ and Neuroblastoma: Failure to Divide and Cull.

Blackstone C.

Dev Cell. 2016 Jan 25;36(2):127-8. doi: 10.1016/j.devcel.2016.01.005.

13.

XAF1 promotes neuroblastoma tumor suppression and is required for KIF1Bβ-mediated apoptosis.

Choo Z, Koh RY, Wallis K, Koh TJ, Kuick CH, Sobrado V, Kenchappa RS, Loh AH, Soh SY, Schlisio S, Chang KT, Chen ZX.

Oncotarget. 2016 Jun 7;7(23):34229-39. doi: 10.18632/oncotarget.8748.

14.

Proline hydroxylation and gene expression.

Kaelin WG.

Annu Rev Biochem. 2005;74:115-28. Review.

PMID:
15952883
16.

Kif1Bbeta isoform is enriched in motor neurons but does not change in a mouse model of amyotrophic lateral sclerosis.

Conforti L, Dell'Agnello C, Calvaresi N, Tortarolo M, Giorgini A, Coleman MP, Bendotti C.

J Neurosci Res. 2003 Mar 1;71(5):732-9.

PMID:
12584731
17.

A germline mutation of the KIF1B beta gene on 1p36 in a family with neural and nonneural tumors.

Yeh IT, Lenci RE, Qin Y, Buddavarapu K, Ligon AH, Leteurtre E, Do Cao C, Cardot-Bauters C, Pigny P, Dahia PL.

Hum Genet. 2008 Oct;124(3):279-85. doi: 10.1007/s00439-008-0553-1. Epub 2008 Aug 26.

PMID:
18726616
18.
19.

CHD5 is a tumor suppressor at human 1p36.

Bagchi A, Papazoglu C, Wu Y, Capurso D, Brodt M, Francis D, Bredel M, Vogel H, Mills AA.

Cell. 2007 Feb 9;128(3):459-75.

20.

In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations.

Rathmell WK, Hickey MM, Bezman NA, Chmielecki CA, Carraway NC, Simon MC.

Cancer Res. 2004 Dec 1;64(23):8595-603.

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