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Items: 1 to 20 of 41

1.

Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia.

Carlucci A, Adornetto A, Scorziello A, Viggiano D, Foca M, Cuomo O, Annunziato L, Gottesman M, Feliciello A.

EMBO J. 2008 Apr 9;27(7):1073-84. doi: 10.1038/emboj.2008.33. Epub 2008 Mar 6.

2.

Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia.

Kim H, Scimia MC, Wilkinson D, Trelles RD, Wood MR, Bowtell D, Dillin A, Mercola M, Ronai ZA.

Mol Cell. 2011 Nov 18;44(4):532-44. doi: 10.1016/j.molcel.2011.08.045.

3.

Mitochondrial AKAP121 links cAMP and src signaling to oxidative metabolism.

Livigni A, Scorziello A, Agnese S, Adornetto A, Carlucci A, Garbi C, Castaldo I, Annunziato L, Avvedimento EV, Feliciello A.

Mol Biol Cell. 2006 Jan;17(1):263-71. Epub 2005 Oct 26.

4.

Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis.

Schiattarella GG, Cattaneo F, Pironti G, Magliulo F, Carotenuto G, Pirozzi M, Polishchuk R, Borzacchiello D, Paolillo R, Oliveti M, Boccella N, Avvedimento M, Sepe M, Lombardi A, Busiello RA, Trimarco B, Esposito G, Feliciello A, Perrino C.

PLoS One. 2016 May 2;11(5):e0154076. doi: 10.1371/journal.pone.0154076. eCollection 2016. Erratum in: PLoS One. 2016;11(7):e0158934.

5.

Regulation of Sprouty2 stability by mammalian Seven-in-Absentia homolog 2.

Nadeau RJ, Toher JL, Yang X, Kovalenko D, Friesel R.

J Cell Biochem. 2007 Jan 1;100(1):151-60.

PMID:
16888801
6.

NCX3 regulates mitochondrial Ca(2+) handling through the AKAP121-anchored signaling complex and prevents hypoxia-induced neuronal death.

Scorziello A, Savoia C, Sisalli MJ, Adornetto A, Secondo A, Boscia F, Esposito A, Polishchuk EV, Polishchuk RS, Molinaro P, Carlucci A, Lignitto L, Di Renzo G, Feliciello A, Annunziato L.

J Cell Sci. 2013 Dec 15;126(Pt 24):5566-77. doi: 10.1242/jcs.129668. Epub 2013 Oct 7.

7.

Seven in absentia homolog 2 (Siah2) protein is a regulator of NF-E2-related factor 2 (Nrf2).

Baba K, Morimoto H, Imaoka S.

J Biol Chem. 2013 Jun 21;288(25):18393-405. doi: 10.1074/jbc.M112.438762. Epub 2013 May 3.

8.

Pivotal role of AKAP121 in mitochondrial physiology.

Czachor A, Failla A, Lockey R, Kolliputi N.

Am J Physiol Cell Physiol. 2016 Apr 15;310(8):C625-8. doi: 10.1152/ajpcell.00292.2015. Epub 2016 Jan 28. Review.

9.

Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signaling.

Cardone L, Carlucci A, Affaitati A, Livigni A, DeCristofaro T, Garbi C, Varrone S, Ullrich A, Gottesman ME, Avvedimento EV, Feliciello A.

Mol Cell Biol. 2004 Jun;24(11):4613-26.

10.

Parkin Protects against Oxygen-Glucose Deprivation/Reperfusion Insult by Promoting Drp1 Degradation.

Tang J, Hu Z, Tan J, Yang S, Zeng L.

Oxid Med Cell Longev. 2016;2016:8474303. doi: 10.1155/2016/8474303. Epub 2016 Aug 14.

11.

Control of mitochondria dynamics and oxidative metabolism by cAMP, AKAPs and the proteasome.

Carlucci A, Lignitto L, Feliciello A.

Trends Cell Biol. 2008 Dec;18(12):604-13. doi: 10.1016/j.tcb.2008.09.006. Epub 2008 Oct 24. Review.

PMID:
18951795
12.

Essential role of A-kinase anchor protein 121 for cAMP signaling to mitochondria.

Affaitati A, Cardone L, de Cristofaro T, Carlucci A, Ginsberg MD, Varrone S, Gottesman ME, Avvedimento EV, Feliciello A.

J Biol Chem. 2003 Feb 7;278(6):4286-94. Epub 2002 Nov 8.

13.

Mitochondrial A-kinase anchoring protein 121 binds type II protein kinase A and enhances steroidogenic acute regulatory protein-mediated steroidogenesis in MA-10 mouse leydig tumor cells.

Dyson MT, Jones JK, Kowalewski MP, Manna PR, Alonso M, Gottesman ME, Stocco DM.

Biol Reprod. 2008 Feb;78(2):267-77. Epub 2007 Nov 7.

PMID:
17989356
14.

Expression of a kinase anchor protein 121 is regulated by hormones in thyroid and testicular germ cells.

Feliciello A, Rubin CS, Avvedimento EV, Gottesman ME.

J Biol Chem. 1998 Sep 4;273(36):23361-6.

15.

Mutual regulation between Polo-like kinase 3 and SIAH2 E3 ubiquitin ligase defines a regulatory network that fine-tunes the cellular response to hypoxia and nickel.

Li C, Park S, Zhang X, Dai W, Xu D.

J Biol Chem. 2017 Jul 7;292(27):11431-11444. doi: 10.1074/jbc.M116.767178. Epub 2017 May 17.

PMID:
28515325
16.

TIN2 stability is regulated by the E3 ligase Siah2.

Bhanot M, Smith S.

Mol Cell Biol. 2012 Jan;32(2):376-84. doi: 10.1128/MCB.06227-11. Epub 2011 Nov 7.

17.

Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells.

Sarkar TR, Sharan S, Wang J, Pawar SA, Cantwell CA, Johnson PF, Morrison DK, Wang JM, Sterneck E.

Mol Cell Biol. 2012 Jan;32(2):320-32. doi: 10.1128/MCB.05790-11. Epub 2011 Oct 28.

18.

An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response.

Calzado MA, de la Vega L, Möller A, Bowtell DD, Schmitz ML.

Nat Cell Biol. 2009 Jan;11(1):85-91. doi: 10.1038/ncb1816. Epub 2008 Nov 30.

PMID:
19043406
19.

An N-terminal SIAH-interacting motif regulates the stability of the ubiquitin specific protease (USP)-19.

Velasco K, Zhao B, Callegari S, Altun M, Liu H, Hassink G, Masucci MG, Lindsten K.

Biochem Biophys Res Commun. 2013 Apr 19;433(4):390-5. doi: 10.1016/j.bbrc.2013.02.094. Epub 2013 Mar 13.

PMID:
23500468
20.

Mutual regulation between SIAH2 and DYRK2 controls hypoxic and genotoxic signaling pathways.

Pérez M, García-Limones C, Zapico I, Marina A, Schmitz ML, Muñoz E, Calzado MA.

J Mol Cell Biol. 2012 Oct;4(5):316-30. doi: 10.1093/jmcb/mjs047. Epub 2012 Aug 9.

PMID:
22878263

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