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Evidence that tRNA modifying enzymes are important in vivo targets for 5-fluorouracil in yeast.

Gustavsson M, Ronne H.

RNA. 2008 Apr;14(4):666-74. doi: 10.1261/rna.966208. Epub 2008 Feb 26.


Unexpected expansion of tRNA substrate recognition by the yeast m1G9 methyltransferase Trm10.

Swinehart WE, Henderson JC, Jackman JE.

RNA. 2013 Aug;19(8):1137-46. doi: 10.1261/rna.039651.113. Epub 2013 Jun 21.


tRNAHis 5-methylcytidine levels increase in response to several growth arrest conditions in Saccharomyces cerevisiae.

Preston MA, D'Silva S, Kon Y, Phizicky EM.

RNA. 2013 Feb;19(2):243-56. doi: 10.1261/rna.035808.112. Epub 2012 Dec 18.


Rapid tRNA decay can result from lack of nonessential modifications.

Alexandrov A, Chernyakov I, Gu W, Hiley SL, Hughes TR, Grayhack EJ, Phizicky EM.

Mol Cell. 2006 Jan 6;21(1):87-96.


The yeast rapid tRNA decay pathway competes with elongation factor 1A for substrate tRNAs and acts on tRNAs lacking one or more of several modifications.

Dewe JM, Whipple JM, Chernyakov I, Jaramillo LN, Phizicky EM.

RNA. 2012 Oct;18(10):1886-96. doi: 10.1261/rna.033654.112. Epub 2012 Aug 15.


tRNA transfers to the limelight.

Hopper AK, Phizicky EM.

Genes Dev. 2003 Jan 15;17(2):162-80. Review. No abstract available.


Cytoplasmic splicing of tRNA in Saccharomyces cerevisiae.

Yoshihisa T, Ohshima C, Yunoki-Esaki K, Endo T.

Genes Cells. 2007 Mar;12(3):285-97.


tRNA modifying enzymes, NSUN2 and METTL1, determine sensitivity to 5-fluorouracil in HeLa cells.

Okamoto M, Fujiwara M, Hori M, Okada K, Yazama F, Konishi H, Xiao Y, Qi G, Shimamoto F, Ota T, Temme A, Tatsuka M.

PLoS Genet. 2014 Sep 18;10(9):e1004639. doi: 10.1371/journal.pgen.1004639. eCollection 2014 Sep.


Major identity determinants for enzymatic formation of ribothymidine and pseudouridine in the T psi-loop of yeast tRNAs.

Becker HF, Motorin Y, Sissler M, Florentz C, Grosjean H.

J Mol Biol. 1997 Dec 12;274(4):505-18.


Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1.

Chernyakov I, Whipple JM, Kotelawala L, Grayhack EJ, Phizicky EM.

Genes Dev. 2008 May 15;22(10):1369-80. doi: 10.1101/gad.1654308. Epub 2008 Apr 28.


Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae.

Kadaba S, Krueger A, Trice T, Krecic AM, Hinnebusch AG, Anderson J.

Genes Dev. 2004 Jun 1;18(11):1227-40. Epub 2004 May 14.


tRNA and protein methylase complexes mediate zymocin toxicity in yeast.

Studte P, Zink S, Jablonowski D, Bär C, von der Haar T, Tuite MF, Schaffrath R.

Mol Microbiol. 2008 Sep;69(5):1266-77. doi: 10.1111/j.1365-2958.2008.06358.x. Epub 2008 Jul 24.


PTA1, an essential gene of Saccharomyces cerevisiae affecting pre-tRNA processing.

O'Connor JP, Peebles CL.

Mol Cell Biol. 1992 Sep;12(9):3843-56.


Enzymatic formation of N2,N2-dimethylguanosine in eukaryotic tRNA: importance of the tRNA architecture.

Edqvist J, Stråby KB, Grosjean H.

Biochimie. 1995;77(1-2):54-61. Review.


Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits.

White J, Li Z, Sardana R, Bujnicki JM, Marcotte EM, Johnson AW.

Mol Cell Biol. 2008 May;28(10):3151-61. doi: 10.1128/MCB.01674-07. Epub 2008 Mar 10.

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