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Items: 1 to 20 of 154

1.

The multiple roles of CUX1: insights from mouse models and cell-based assays.

Sansregret L, Nepveu A.

Gene. 2008 Apr 15;412(1-2):84-94. doi: 10.1016/j.gene.2008.01.017. Review.

PMID:
18313863
3.

Biochemical characterization of the mammalian Cux2 protein.

Gingras H, Cases O, Krasilnikova M, Bérubé G, Nepveu A.

Gene. 2005 Jan 3;344:273-85.

PMID:
15656993
4.

Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types.

Cadieux C, Kedinger V, Yao L, Vadnais C, Drossos M, Paquet M, Nepveu A.

Cancer Res. 2009 Sep 15;69(18):7188-97. doi: 10.1158/0008-5472.CAN-08-4899.

5.

CUX1 transcription factor is a downstream effector of the proteinase-activated receptor 2 (PAR2).

Wilson BJ, Harada R, LeDuy L, Hollenberg MD, Nepveu A.

J Biol Chem. 2009 Jan 2;284(1):36-45. doi: 10.1074/jbc.M803808200.

6.

CUX1 transcription factors: from biochemical activities and cell-based assays to mouse models and human diseases.

Hulea L, Nepveu A.

Gene. 2012 Apr 10;497(1):18-26. doi: 10.1016/j.gene.2012.01.039. Review.

PMID:
22306263
7.

Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice.

Siam R, Harada R, Cadieux C, Battat R, Vadnais C, Nepveu A.

Mol Cancer. 2009 Aug 5;8:60. doi: 10.1186/1476-4598-8-60.

8.

Carboxyl-terminal proteolytic processing of CUX1 by a caspase enables transcriptional activation in proliferating cells.

Truscott M, Denault JB, Goulet B, Leduy L, Salvesen GS, Nepveu A.

J Biol Chem. 2007 Oct 12;282(41):30216-26.

9.

Transgenic mice expressing the p75 CCAAT-displacement protein/Cut homeobox isoform develop a myeloproliferative disease-like myeloid leukemia.

Cadieux C, Fournier S, Peterson AC, Bédard C, Bedell BJ, Nepveu A.

Cancer Res. 2006 Oct 1;66(19):9492-501.

10.

Characterization of a tissue-specific CDP/Cux isoform, p75, activated in breast tumor cells.

Goulet B, Watson P, Poirier M, Leduy L, Bérubé G, Meterissian S, Jolicoeur P, Nepveu A.

Cancer Res. 2002 Nov 15;62(22):6625-33.

11.

Polycystic kidneys caused by sustained expression of Cux1 isoform p75.

Cadieux C, Harada R, Paquet M, Côté O, Trudel M, Nepveu A, Bouchard M.

J Biol Chem. 2008 May 16;283(20):13817-24. doi: 10.1074/jbc.M709332200.

12.
13.

p110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes.

Truscott M, Harada R, Vadnais C, Robert F, Nepveu A.

Mol Cell Biol. 2008 May;28(10):3127-38. doi: 10.1128/MCB.02089-07.

14.

The Promyelocytic Leukemia Zinc Finger (PLZF ) gene is a novel transcriptional target of the CCAAT-Displacement-protein (CUX1) repressor.

Fréchette I, Darsigny M, Brochu-Gaudreau K, Jones C, Boudreau F.

FEBS J. 2010 Oct;277(20):4241-53.

PMID:
20945532
16.

CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness.

Michl P, Ramjaun AR, Pardo OE, Warne PH, Wagner M, Poulsom R, D'Arrigo C, Ryder K, Menke A, Gress T, Downward J.

Cancer Cell. 2005 Jun;7(6):521-32.

17.

Proteolytic processing of cut homeobox 1 by neutrophil elastase in the MV4;11 myeloid leukemia cell line.

Goulet B, Markovic Y, Leduy L, Nepveu A.

Mol Cancer Res. 2008 Apr;6(4):644-53. doi: 10.1158/1541-7786.MCR-07-0268.

18.

Tumor suppressor pRB functions as a co-repressor of the CCAAT displacement protein (CDP/cut) to regulate cell cycle controlled histone H4 transcription.

Gupta S, Luong MX, Bleuming SA, Miele A, Luong M, Young D, Knudsen ES, Van Wijnen AJ, Stein JL, Stein GS.

J Cell Physiol. 2003 Sep;196(3):541-56.

PMID:
12891711
19.

Glutamate receptor GRIA3--target of CUX1 and mediator of tumor progression in pancreatic cancer.

Ripka S, Riedel J, Neesse A, Griesmann H, Buchholz M, Ellenrieder V, Moeller F, Barth P, Gress TM, Michl P.

Neoplasia. 2010 Aug;12(8):659-67.

20.

p110 CUX1 homeodomain protein stimulates cell migration and invasion in part through a regulatory cascade culminating in the repression of E-cadherin and occludin.

Kedinger V, Sansregret L, Harada R, Vadnais C, Cadieux C, Fathers K, Park M, Nepveu A.

J Biol Chem. 2009 Oct 2;284(40):27701-11. doi: 10.1074/jbc.M109.031849.

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