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Worldwide distribution of NAT2 diversity: implications for NAT2 evolutionary history.

Sabbagh A, Langaney A, Darlu P, Gérard N, Krishnamoorthy R, Poloni ES.

BMC Genet. 2008 Feb 27;9:21. doi: 10.1186/1471-2156-9-21.


Genotyping of the polymorphic N-acetyltransferase (NAT2*) gene locus in two native African populations.

Deloménie C, Sica L, Grant DM, Krishnamoorthy R, Dupret JM.

Pharmacogenetics. 1996 Apr;6(2):177-85.


Variation in NAT2 acetylation phenotypes is associated with differences in food-producing subsistence modes and ecoregions in Africa.

Podgorná E, Diallo I, Vangenot C, Sanchez-Mazas A, Sabbagh A, Černý V, Poloni ES.

BMC Evol Biol. 2015 Dec 1;15:263. doi: 10.1186/s12862-015-0543-6.


Arylamine N-acetyltransferase 2 (NAT2) genetic diversity and traditional subsistence: a worldwide population survey.

Sabbagh A, Darlu P, Crouau-Roy B, Poloni ES.

PLoS One. 2011 Apr 6;6(4):e18507. doi: 10.1371/journal.pone.0018507.


Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.

Patin E, Barreiro LB, Sabeti PC, Austerlitz F, Luca F, Sajantila A, Behar DM, Semino O, Sakuntabhai A, Guiso N, Gicquel B, McElreavey K, Harding RM, Heyer E, Quintana-Murci L.

Am J Hum Genet. 2006 Mar;78(3):423-36. Epub 2006 Jan 13.


CYP3A4*1B and NAT2*14 alleles in a native African population.

Cavaco I, Reis R, Gil JP, Ribeiro V.

Clin Chem Lab Med. 2003 Apr;41(4):606-9.


Comparison of genetic polymorphisms of the NAT2 gene between Korean and four other ethnic groups.

Kang TS, Jin SK, Lee JE, Woo SW, Roh J.

J Clin Pharm Ther. 2009 Dec;34(6):709-18. doi: 10.1111/j.1365-2710.2009.01065.x.


Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene.

Patin E, Harmant C, Kidd KK, Kidd J, Froment A, Mehdi SQ, Sica L, Heyer E, Quintana-Murci L.

Hum Mutat. 2006 Jul;27(7):720.


Analysis of nucleotide diversity of NAT2 coding region reveals homogeneity across Native American populations and high intra-population diversity.

Fuselli S, Gilman RH, Chanock SJ, Bonatto SL, De Stefano G, Evans CA, Labuda D, Luiselli D, Salzano FM, Soto G, Vallejo G, Sajantila A, Pettener D, Tarazona-Santos E.

Pharmacogenomics J. 2007 Apr;7(2):144-52. Epub 2006 Jul 18.


Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia.

Magalon H, Patin E, Austerlitz F, Hegay T, Aldashev A, Quintana-Murci L, Heyer E.

Eur J Hum Genet. 2008 Feb;16(2):243-51. Epub 2007 Nov 28.


Interethnic diversity of NAT2 polymorphisms in Brazilian admixed populations.

Talbot J, Magno LA, Santana CV, Sousa SM, Melo PR, Correa RX, Di Pietro G, Rios-Santos F.

BMC Genet. 2010 Oct 5;11:87. doi: 10.1186/1471-2156-11-87.


Interethnic and intraethnic variability of NAT2 single nucleotide polymorphisms.

García-Martín E.

Curr Drug Metab. 2008 Jul;9(6):487-97. Review.


Impact of population diversity on the prediction of 7-SNP NAT2 phenotypes using the tagSNP rs1495741 or paired SNPs.

Suarez-Kurtz G, Sortica VA, Vargens DD, Bruxel EM, Petzl-Erler ML, Tsuneto LT, Hutz MH.

Pharmacogenet Genomics. 2012 Apr;22(4):305-9. doi: 10.1097/FPC.0b013e3283519c7c. Erratum in: Pharmacogenet Genomics. 2012 May;22(5):397. Petz-Erler, Maria-Luiza [corrected to Petzl-Erler, Maria-Luiza].


A homogenizing process of selection has maintained an "ultra-slow" acetylation NAT2 variant in humans.

Patillon B, Luisi P, Poloni ES, Boukouvala S, Darlu P, Genin E, Sabbagh A.

Hum Biol. 2014 Summer;86(3):185-214.


Genetic profile of the arylamine N-acetyltransferase 2 coding gene among individuals from two different regions of Brazil.

Teixeira RL, Miranda AB, Pacheco AG, Lopes MQ, Fonseca-Costa J, Rabahi MF, Melo HM, Kritski AL, Mello FC, Suffys PN, Santos AR.

Mutat Res. 2007 Nov 1;624(1-2):31-40. Epub 2007 Apr 19.


Study of NAT2 genetic polymorphism in West African subjects: example of an healthy non-smoker Senegalese population.

Touré A, Diop C, Cabral M, Fall M, Lhermitte M, Diouf A, Broly F, Allorge D.

Mol Biol Rep. 2012 Dec;39(12):10489-96. doi: 10.1007/s11033-012-1931-2. Epub 2012 Oct 7.


Arylamine N-acetyltransferase 2 genotypes in a Mexican population.

Taja-Chayeb L, Agúndez JA, Miguez-Muñoz C, Chavez-Blanco A, Dueñas-Gonzalez A.

Genet Mol Res. 2012 Apr 27;11(2):1082-92. doi: 10.4238/2012.April.27.7.


Genotyping NAT2 with only two SNPs (rs1041983 and rs1801280) outperforms the tagging SNP rs1495741 and is equivalent to the conventional 7-SNP NAT2 genotype.

Selinski S, Blaszkewicz M, Lehmann ML, Ovsiannikov D, Moormann O, Guballa C, Kress A, Truss MC, Gerullis H, Otto T, Barski D, Niegisch G, Albers P, Frees S, Brenner W, Thüroff JW, Angeli-Greaves M, Seidel T, Roth G, Dietrich H, Ebbinghaus R, Prager HM, Bolt HM, Falkenstein M, Zimmermann A, Klein T, Reckwitz T, Roemer HC, Löhlein D, Weistenhöfer W, Schöps W, Hassan Rizvi SA, Aslam M, Bánfi G, Romics I, Steffens M, Ekici AB, Winterpacht A, Ickstadt K, Schwender H, Hengstler JG, Golka K.

Pharmacogenet Genomics. 2011 Oct;21(10):673-8. doi: 10.1097/FPC.0b013e3283493a23.


Unraveling ambiguous NAT2 genotyping data.

Agúndez JA, Golka K, Martínez C, Selinski S, Blaszkewicz M, García-Martín E.

Clin Chem. 2008 Aug;54(8):1390-4. doi: 10.1373/clinchem.2008.105569.


A single nucleotide polymorphism tags variation in the arylamine N-acetyltransferase 2 phenotype in populations of European background.

García-Closas M, Hein DW, Silverman D, Malats N, Yeager M, Jacobs K, Doll MA, Figueroa JD, Baris D, Schwenn M, Kogevinas M, Johnson A, Chatterjee N, Moore LE, Moeller T, Real FX, Chanock S, Rothman N.

Pharmacogenet Genomics. 2011 Apr;21(4):231-6. doi: 10.1097/FPC.0b013e32833e1b54.

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