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Items: 1 to 20 of 106

1.

The RNA-binding and adaptor protein Sam68 modulates signal-dependent splicing and transcriptional activity of the androgen receptor.

Rajan P, Gaughan L, Dalgliesh C, El-Sherif A, Robson CN, Leung HY, Elliott DJ.

J Pathol. 2008 May;215(1):67-77. doi: 10.1002/path.2324.

PMID:
18273831
2.

The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7.

Stockley J, Markert E, Zhou Y, Robson CN, Elliott DJ, Lindberg J, Leung HY, Rajan P.

Sci Rep. 2015 Aug 27;5:13426. doi: 10.1038/srep13426.

3.

The transcriptional co-activator SND1 is a novel regulator of alternative splicing in prostate cancer cells.

Cappellari M, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Saarikettu J, Silvennoinen O, Sette C.

Oncogene. 2014 Jul 17;33(29):3794-802. doi: 10.1038/onc.2013.360. Epub 2013 Sep 2.

PMID:
23995791
4.

The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer.

Clark EL, Coulson A, Dalgliesh C, Rajan P, Nicol SM, Fleming S, Heer R, Gaughan L, Leung HY, Elliott DJ, Fuller-Pace FV, Robson CN.

Cancer Res. 2008 Oct 1;68(19):7938-46. doi: 10.1158/0008-5472.CAN-08-0932.

5.

Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68.

Paronetto MP, Cappellari M, Busà R, Pedrotti S, Vitali R, Comstock C, Hyslop T, Knudsen KE, Sette C.

Cancer Res. 2010 Jan 1;70(1):229-39. doi: 10.1158/0008-5472.CAN-09-2788. Epub 2009 Dec 22.

6.

p68/DdX5 supports β-catenin & RNAP II during androgen receptor mediated transcription in prostate cancer.

Clark EL, Hadjimichael C, Temperley R, Barnard A, Fuller-Pace FV, Robson CN.

PLoS One. 2013;8(1):e54150. doi: 10.1371/journal.pone.0054150. Epub 2013 Jan 17.

7.
8.

FOXP1 is an androgen-responsive transcription factor that negatively regulates androgen receptor signaling in prostate cancer cells.

Takayama K, Horie-Inoue K, Ikeda K, Urano T, Murakami K, Hayashizaki Y, Ouchi Y, Inoue S.

Biochem Biophys Res Commun. 2008 Sep 19;374(2):388-93. doi: 10.1016/j.bbrc.2008.07.056. Epub 2008 Jul 18.

PMID:
18640093
9.

RNA splicing and splicing regulator changes in prostate cancer pathology.

Munkley J, Livermore K, Rajan P, Elliott DJ.

Hum Genet. 2017 Sep;136(9):1143-1154. doi: 10.1007/s00439-017-1792-9. Epub 2017 Apr 5. Review.

10.

Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin.

Busà R, Geremia R, Sette C.

Nucleic Acids Res. 2010 May;38(9):3005-18. doi: 10.1093/nar/gkq004. Epub 2010 Jan 27.

12.

MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.

Nilsson EM, Laursen KB, Whitchurch J, McWilliam A, Ødum N, Persson JL, Heery DM, Gudas LJ, Mongan NP.

Oncotarget. 2015 Nov 3;6(34):35710-25. doi: 10.18632/oncotarget.5958.

13.

Dissociation between androgen responsiveness for malignant growth vs. expression of prostate specific differentiation markers PSA, hK2, and PSMA in human prostate cancer models.

Denmeade SR, Sokoll LJ, Dalrymple S, Rosen DM, Gady AM, Bruzek D, Ricklis RM, Isaacs JT.

Prostate. 2003 Mar 1;54(4):249-57.

PMID:
12539223
14.

The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling.

Correa RG, Krajewska M, Ware CF, Gerlic M, Reed JC.

Oncotarget. 2014 Mar 30;5(6):1666-82.

15.

Peroxisome proliferator-activated receptor gamma coactivator-1alpha interacts with the androgen receptor (AR) and promotes prostate cancer cell growth by activating the AR.

Shiota M, Yokomizo A, Tada Y, Inokuchi J, Tatsugami K, Kuroiwa K, Uchiumi T, Fujimoto N, Seki N, Naito S.

Mol Endocrinol. 2010 Jan;24(1):114-27. doi: 10.1210/me.2009-0302. Epub 2009 Nov 2.

16.

Identification of novel androgen receptor target genes in prostate cancer.

Jariwala U, Prescott J, Jia L, Barski A, Pregizer S, Cogan JP, Arasheben A, Tilley WD, Scher HI, Gerald WL, Buchanan G, Coetzee GA, Frenkel B.

Mol Cancer. 2007 Jun 6;6:39.

17.

Inhibition of MAPK-signaling pathway promotes the interaction of the corepressor SMRT with the human androgen receptor and mediates repression of prostate cancer cell growth in the presence of antiandrogens.

Eisold M, Asim M, Eskelinen H, Linke T, Baniahmad A.

J Mol Endocrinol. 2009 May;42(5):429-35. doi: 10.1677/JME-08-0084. Epub 2009 Feb 17.

PMID:
19223455
18.

The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy.

Pedrotti S, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Stamm S, Manley JL, Sette C.

EMBO J. 2010 Apr 7;29(7):1235-47. doi: 10.1038/emboj.2010.19. Epub 2010 Feb 25.

19.

Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1.

Zhang Y, Fondell JD, Wang Q, Xia X, Cheng A, Lu ML, Hamburger AW.

Oncogene. 2002 Aug 15;21(36):5609-18.

20.

Protein kinase D1 (PKD1) influences androgen receptor (AR) function in prostate cancer cells.

Mak P, Jaggi M, Syed V, Chauhan SC, Hassan S, Biswas H, Balaji KC.

Biochem Biophys Res Commun. 2008 Sep 5;373(4):618-23. doi: 10.1016/j.bbrc.2008.06.097. Epub 2008 Jul 3.

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