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Items: 1 to 20 of 92

1.

A gas chromatographic-mass spectrometric approach to examining stereoselective interaction of human plasma proteins with soman.

Yeung DT, Smith JR, Sweeney RE, Lenz DE, Cerasoli DM.

J Anal Toxicol. 2008 Jan-Feb;32(1):86-91.

PMID:
18269799
2.

Direct detection of stereospecific soman hydrolysis by wild-type human serum paraoxonase.

Yeung DT, Smith JR, Sweeney RE, Lenz DE, Cerasoli DM.

FEBS J. 2007 Mar;274(5):1183-91. Epub 2007 Feb 5.

3.

Binding and hydrolysis of soman by human serum albumin.

Li B, Nachon F, Froment MT, Verdier L, Debouzy JC, Brasme B, Gillon E, Schopfer LM, Lockridge O, Masson P.

Chem Res Toxicol. 2008 Feb;21(2):421-31. doi: 10.1021/tx700339m. Epub 2007 Dec 29.

PMID:
18163544
4.

Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: a mini review.

Lenz DE, Yeung D, Smith JR, Sweeney RE, Lumley LA, Cerasoli DM.

Toxicology. 2007 Apr 20;233(1-3):31-9. Epub 2006 Dec 1. Review.

PMID:
17188793
5.

Modifications to the organophosphorus nerve agent-protein adduct refluoridation method for retrospective analysis of nerve agent exposures.

Holland KE, Solano MI, Johnson RC, Maggio VL, Barr JR.

J Anal Toxicol. 2008 Jan-Feb;32(1):116-24.

PMID:
18269803
6.

Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase.

Barakat NH, Zheng X, Gilley CB, MacDonald M, Okolotowicz K, Cashman JR, Vyas S, Beck JM, Hadad CM, Zhang J.

Chem Res Toxicol. 2009 Oct;22(10):1669-79. doi: 10.1021/tx900096j.

7.

Enhanced stereoselective hydrolysis of toxic organophosphates by directly evolved variants of mammalian serum paraoxonase.

Amitai G, Gaidukov L, Adani R, Yishay S, Yacov G, Kushnir M, Teitlboim S, Lindenbaum M, Bel P, Khersonsky O, Tawfik DS, Meshulam H.

FEBS J. 2006 May;273(9):1906-19.

8.

Asymmetric fluorogenic organophosphates for the development of active organophosphate hydrolases with reversed stereoselectivity.

Amitai G, Adani R, Yacov G, Yishay S, Teitlboim S, Tveria L, Limanovich O, Kushnir M, Meshulam H.

Toxicology. 2007 Apr 20;233(1-3):187-98. Epub 2006 Oct 13.

PMID:
17129656
9.

Stereoselective detoxification of chiral sarin and soman analogues by phosphotriesterase.

Li WS, Lum KT, Chen-Goodspeed M, Sogorb MA, Raushel FM.

Bioorg Med Chem. 2001 Aug;9(8):2083-91.

PMID:
11504644
10.

Human paraoxonase double mutants hydrolyze V and G class organophosphorus nerve agents.

Kirby SD, Norris JR, Richard Smith J, Bahnson BJ, Cerasoli DM.

Chem Biol Interact. 2013 Mar 25;203(1):181-5. doi: 10.1016/j.cbi.2012.10.023. Epub 2012 Nov 15.

PMID:
23159884
11.

Efficient hydrolysis of the chemical warfare nerve agent tabun by recombinant and purified human and rabbit serum paraoxonase 1.

Valiyaveettil M, Alamneh Y, Biggemann L, Soojhawon I, Doctor BP, Nambiar MP.

Biochem Biophys Res Commun. 2010 Dec 3;403(1):97-102. doi: 10.1016/j.bbrc.2010.10.125. Epub 2010 Oct 30.

PMID:
21040699
12.

Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin.

Epstein TM, Samanta U, Kirby SD, Cerasoli DM, Bahnson BJ.

Biochemistry. 2009 Apr 21;48(15):3425-35. doi: 10.1021/bi8023527.

13.
14.

Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents.

Tsai PC, Fox N, Bigley AN, Harvey SP, Barondeau DP, Raushel FM.

Biochemistry. 2012 Aug 14;51(32):6463-75. Epub 2012 Jul 31.

15.

Chiral separation of G-type chemical warfare nerve agents via analytical supercritical fluid chromatography.

Kasten SA, Zulli S, Jones JL, Dephillipo T, Cerasoli DM.

Chirality. 2014 Dec;26(12):817-24. doi: 10.1002/chir.22368. Epub 2014 Oct 9.

16.

Hydrolysis of organophosphorus nerve agent soman by the monoclonal antibodies elicited against an oxyphosphorane hapten.

Yli-Kauhaluoma J, Humppi T, Yliniemelä A.

Acta Chem Scand. 1999 Jul;53(7):473-9.

PMID:
10423832
18.

In search of a catalytic bioscavenger for the prophylaxis of nerve agent toxicity.

diTargiani RC, Chandrasekaran L, Belinskaya T, Saxena A.

Chem Biol Interact. 2010 Sep 6;187(1-3):349-54. doi: 10.1016/j.cbi.2010.02.021. Epub 2010 Feb 20.

PMID:
20176006
19.

Stereochemical specificity of organophosphorus acid anhydrolase toward p-nitrophenyl analogs of soman and sarin.

Hill CM, Li WS, Cheng TC, DeFrank JJ, Raushel FM.

Bioorg Chem. 2001 Feb;29(1):27-35.

PMID:
11300693
20.

Immunodetection of serum albumin adducts as biomarkers for organophosphorus exposure.

Chen S, Zhang J, Lumley L, Cashman JR.

J Pharmacol Exp Ther. 2013 Feb;344(2):531-41. doi: 10.1124/jpet.112.201368. Epub 2012 Nov 28.

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