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Items: 1 to 20 of 125

1.

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.

Patel V, Li L, Cobo-Stark P, Shao X, Somlo S, Lin F, Igarashi P.

Hum Mol Genet. 2008 Jun 1;17(11):1578-90. doi: 10.1093/hmg/ddn045. Epub 2008 Feb 9.

2.

Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease.

Lin F, Hiesberger T, Cordes K, Sinclair AM, Goldstein LS, Somlo S, Igarashi P.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5286-91. Epub 2003 Apr 2.

3.

Combined deletion of Vhl, Trp53 and Kif3a causes cystic and neoplastic renal lesions.

Guinot A, Lehmann H, Wild PJ, Frew IJ.

J Pathol. 2016 Jul;239(3):365-73. doi: 10.1002/path.4736. Epub 2016 May 30.

PMID:
27126173
4.

Cystic gene dosage influences kidney lesions after nephron reduction.

Le Corre S, Viau A, Burtin M, El-Karoui K, Cnops Y, Terryn S, Debaix H, Bérissi S, Gubler MC, Devuyst O, Terzi F.

Nephron. 2015;129(1):42-51. doi: 10.1159/000369312. Epub 2014 Dec 19.

PMID:
25531116
5.

Advances in the pathogenesis and treatment of polycystic kidney disease.

Patel V, Chowdhury R, Igarashi P.

Curr Opin Nephrol Hypertens. 2009 Mar;18(2):99-106. doi: 10.1097/MNH.0b013e3283262ab0. Review.

6.

Polycystic kidney disease: the cilium as a common pathway in cystogenesis.

Lina F, Satlinb LM.

Curr Opin Pediatr. 2004 Apr;16(2):171-6. Review.

PMID:
15021197
7.

Putative roles of cilia in polycystic kidney disease.

Winyard P, Jenkins D.

Biochim Biophys Acta. 2011 Oct;1812(10):1256-62. doi: 10.1016/j.bbadis.2011.04.012. Epub 2011 May 8. Review.

8.

Polycystic kidney disease and the renal cilium.

Deane JA, Ricardo SD.

Nephrology (Carlton). 2007 Dec;12(6):559-64. Review.

PMID:
17995581
9.

Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice.

Lantinga-van Leeuwen IS, Leonhard WN, van der Wal A, Breuning MH, de Heer E, Peters DJ.

Hum Mol Genet. 2007 Dec 15;16(24):3188-96. Epub 2007 Oct 11.

PMID:
17932118
10.

Polycystic kidney disease: cell division without a c(l)ue?

Simons M, Walz G.

Kidney Int. 2006 Sep;70(5):854-64. Epub 2006 Jun 28. Review.

11.

Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways.

Happé H, Leonhard WN, van der Wal A, van de Water B, Lantinga-van Leeuwen IS, Breuning MH, de Heer E, Peters DJ.

Hum Mol Genet. 2009 Jul 15;18(14):2532-42. doi: 10.1093/hmg/ddp190. Epub 2009 Apr 28.

PMID:
19401297
12.

Modeling ciliopathies: Primary cilia in development and disease.

Quinlan RJ, Tobin JL, Beales PL.

Curr Top Dev Biol. 2008;84:249-310. doi: 10.1016/S0070-2153(08)00605-4. Review.

PMID:
19186246
13.

Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease.

Davenport JR, Watts AJ, Roper VC, Croyle MJ, van Groen T, Wyss JM, Nagy TR, Kesterson RA, Yoder BK.

Curr Biol. 2007 Sep 18;17(18):1586-94. Epub 2007 Sep 6.

14.

Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis.

Cano DA, Sekine S, Hebrok M.

Gastroenterology. 2006 Dec;131(6):1856-69. Epub 2006 Oct 26.

PMID:
17123526
15.

Loss of oriented cell division does not initiate cyst formation.

Nishio S, Tian X, Gallagher AR, Yu Z, Patel V, Igarashi P, Somlo S.

J Am Soc Nephrol. 2010 Feb;21(2):295-302. doi: 10.1681/ASN.2009060603. Epub 2009 Dec 3.

16.

Apico-basal polarity in polycystic kidney disease epithelia.

Wilson PD.

Biochim Biophys Acta. 2011 Oct;1812(10):1239-48. doi: 10.1016/j.bbadis.2011.05.008. Epub 2011 Jun 1. Review.

17.

Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney disease.

Chen Y, Chiang HC, Litchfield P, Pena M, Juang C, Riley DJ.

J Biomed Sci. 2014 Jul 17;21:63. doi: 10.1186/s12929-014-0063-5.

18.

Galectin-3 associates with the primary cilium and modulates cyst growth in congenital polycystic kidney disease.

Chiu MG, Johnson TM, Woolf AS, Dahm-Vicker EM, Long DA, Guay-Woodford L, Hillman KA, Bawumia S, Venner K, Hughes RC, Poirier F, Winyard PJ.

Am J Pathol. 2006 Dec;169(6):1925-38.

19.

Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney Disease.

Leonhard WN, Zandbergen M, Veraar K, van den Berg S, van der Weerd L, Breuning M, de Heer E, Peters DJ.

J Am Soc Nephrol. 2015 Jun;26(6):1322-33. doi: 10.1681/ASN.2013080864. Epub 2014 Oct 31.

20.

Pkd1 inactivation induced in adulthood produces focal cystic disease.

Takakura A, Contrino L, Beck AW, Zhou J.

J Am Soc Nephrol. 2008 Dec;19(12):2351-63. doi: 10.1681/ASN.2007101139. Epub 2008 Sep 5.

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