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Items: 1 to 20 of 111

1.

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.

Yamanaka K, Chun SJ, Boillee S, Fujimori-Tonou N, Yamashita H, Gutmann DH, Takahashi R, Misawa H, Cleveland DW.

Nat Neurosci. 2008 Mar;11(3):251-3. doi: 10.1038/nn2047. Epub 2008 Feb 3.

2.

Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis.

Almer G, Vukosavic S, Romero N, Przedborski S.

J Neurochem. 1999 Jun;72(6):2415-25.

3.

Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice.

Chen K, Northington FJ, Martin LJ.

Brain Struct Funct. 2010 Mar;214(2-3):219-34. doi: 10.1007/s00429-009-0226-4. Epub 2009 Nov 4.

4.

Onset and progression in inherited ALS determined by motor neurons and microglia.

Boillée S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW.

Science. 2006 Jun 2;312(5778):1389-92.

5.
6.

Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression.

Tortarolo M, Veglianese P, Calvaresi N, Botturi A, Rossi C, Giorgini A, Migheli A, Bendotti C.

Mol Cell Neurosci. 2003 Jun;23(2):180-92.

PMID:
12812752
7.

Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice.

Wang L, Gutmann DH, Roos RP.

Hum Mol Genet. 2011 Jan 15;20(2):286-93. doi: 10.1093/hmg/ddq463. Epub 2010 Oct 20.

PMID:
20962037
8.

System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.

Mesci P, Zaïdi S, Lobsiger CS, Millecamps S, Escartin C, Seilhean D, Sato H, Mallat M, Boillée S.

Brain. 2015 Jan;138(Pt 1):53-68. doi: 10.1093/brain/awu312. Epub 2014 Nov 10.

9.

Motor neuron disease in mice expressing the wild type-like D90A mutant superoxide dismutase-1.

Jonsson PA, Graffmo KS, Brännström T, Nilsson P, Andersen PM, Marklund SL.

J Neuropathol Exp Neurol. 2006 Dec;65(12):1126-36.

PMID:
17146286
10.

Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis.

Vercelli A, Mereuta OM, Garbossa D, Muraca G, Mareschi K, Rustichelli D, Ferrero I, Mazzini L, Madon E, Fagioli F.

Neurobiol Dis. 2008 Sep;31(3):395-405. doi: 10.1016/j.nbd.2008.05.016. Epub 2008 Jun 4.

PMID:
18586098
11.

Loss of glial fibrillary acidic protein marginally accelerates disease progression in a SOD1(H46R) transgenic mouse model of ALS.

Yoshii Y, Otomo A, Pan L, Ohtsuka M, Hadano S.

Neurosci Res. 2011 Jul;70(3):321-9. doi: 10.1016/j.neures.2011.03.006. Epub 2011 Mar 29.

PMID:
21453731
12.

Appearance of phagocytic microglia adjacent to motoneurons in spinal cord tissue from a presymptomatic transgenic rat model of amyotrophic lateral sclerosis.

Sanagi T, Yuasa S, Nakamura Y, Suzuki E, Aoki M, Warita H, Itoyama Y, Uchino S, Kohsaka S, Ohsawa K.

J Neurosci Res. 2010 Sep;88(12):2736-46. doi: 10.1002/jnr.22424.

PMID:
20648658
13.

Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis.

Ferraiuolo L, Higginbottom A, Heath PR, Barber S, Greenald D, Kirby J, Shaw PJ.

Brain. 2011 Sep;134(Pt 9):2627-41. doi: 10.1093/brain/awr193.

14.
15.

Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia.

Xiao Q, Zhao W, Beers DR, Yen AA, Xie W, Henkel JS, Appel SH.

J Neurochem. 2007 Sep;102(6):2008-19. Epub 2007 Jun 7.

16.
17.

Determinants of rapid disease progression in ALS.

Yamanaka K, Cleveland DW.

Neurology. 2005 Dec 27;65(12):1859-60. No abstract available.

PMID:
16380607
18.

Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells.

Marchetto MC, Muotri AR, Mu Y, Smith AM, Cezar GG, Gage FH.

Cell Stem Cell. 2008 Dec 4;3(6):649-57. doi: 10.1016/j.stem.2008.10.001.

19.

Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis.

Kirby J, Ning K, Ferraiuolo L, Heath PR, Ismail A, Kuo SW, Valori CF, Cox L, Sharrack B, Wharton SB, Ince PG, Shaw PJ, Azzouz M.

Brain. 2011 Feb;134(Pt 2):506-17. doi: 10.1093/brain/awq345. Epub 2011 Jan 12.

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