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Items: 1 to 20 of 148

1.

Pharmacokinetics of the main alkamides after administration of three different Echinacea purpurea preparations in humans.

Woelkart K, Dittrich P, Beubler E, Pinl F, Schoop R, Suter A, Bauer R.

Planta Med. 2008 May;74(6):651-6. doi: 10.1055/s-2008-1034284. Epub 2008 Jan 31.

PMID:
18240099
2.

Pharmacokinetics and immunomodulatory effects of phytotherapeutic lozenges (bonbons) with Echinacea purpurea extract.

Guiotto P, Woelkart K, Grabnar I, Voinovich D, Perissutti B, Invernizzi S, Granzotto M, Bauer R.

Phytomedicine. 2008 Aug;15(8):547-54. doi: 10.1016/j.phymed.2008.05.003. Epub 2008 Jun 25.

PMID:
18583121
3.

Absolute/relative bioavailability and metabolism of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides (tetraenes) after intravenous and oral single doses to rats.

Ardjomand-Woelkart K, Kollroser M, Magnes C, Sinner F, Frye RF, Derendorf H, Bauer R, Butterweck V.

Planta Med. 2011 Nov;77(16):1794-9. doi: 10.1055/s-0030-1271120. Epub 2011 May 20.

PMID:
21604240
4.

Bioavailability and pharmacokinetics of Echinacea purpurea preparations and their interaction with the immune system.

Woelkart K, Marth E, Suter A, Schoop R, Raggam RB, Koidl C, Kleinhappl B, Bauer R.

Int J Clin Pharmacol Ther. 2006 Sep;44(9):401-8.

PMID:
16995328
5.

Pharmacokinetics and tissue distribution of dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides after oral administration in rats.

Woelkart K, Frye RF, Derendorf H, Bauer R, Butterweck V.

Planta Med. 2009 Oct;75(12):1306-13. doi: 10.1055/s-0029-1185631. Epub 2009 Apr 27.

PMID:
19399718
6.
7.

The role of alkamides as an active principle of echinacea.

Woelkart K, Bauer R.

Planta Med. 2007 Jun;73(7):615-23. Epub 2007 May 31. Review.

PMID:
17538868
8.

Bioavailability and pharmacokinetics of alkamides from the roots of Echinacea angustifolia in humans.

Woelkart K, Koidl C, Grisold A, Gangemi JD, Turner RB, Marth E, Bauer R.

J Clin Pharmacol. 2005 Jun;45(6):683-9.

PMID:
15901750
9.

The bioanalysis of the major Echinacea purpurea constituents dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides in human plasma using LC-MS/MS.

Goey AK, Rosing H, Meijerman I, Sparidans RW, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Aug 1;902:151-6. doi: 10.1016/j.jchromb.2012.06.022. Epub 2012 Jun 26.

PMID:
22770780
10.

Comparison of Echinacea alkylamide pharmacokinetics between liquid and tablet preparations.

Matthias A, Addison RS, Agnew LL, Bone KM, Watson K, Lehmann RP.

Phytomedicine. 2007 Sep;14(9):587-90. Epub 2007 Feb 7.

PMID:
17289362
11.

Echinacea alkamide disposition and pharmacokinetics in humans after tablet ingestion.

Matthias A, Addison RS, Penman KG, Dickinson RG, Bone KM, Lehmann RP.

Life Sci. 2005 Sep 2;77(16):2018-29.

PMID:
15919096
12.

Bioavailability of Echinacea constituents: Caco-2 monolayers and pharmacokinetics of the alkylamides and caffeic acid conjugates.

Matthias A, Penman KG, Matovic NJ, Bone KM, De Voss JJ, Lehmann RP.

Molecules. 2005 Oct 30;10(10):1242-51.

13.
14.

Metabolomic profiling of liquid Echinacea medicinal products with in vitro inhibitory effects on cytochrome P450 3A4 (CYP3A4).

Modarai M, Yang M, Suter A, Kortenkamp A, Heinrich M.

Planta Med. 2010 Mar;76(4):378-85. doi: 10.1055/s-0029-1186152. Epub 2009 Sep 29.

PMID:
19790031
16.

Comparative metabolomics approach coupled with cell- and gene-based assays for species classification and anti-inflammatory bioactivity validation of Echinacea plants.

Hou CC, Chen CH, Yang NS, Chen YP, Lo CP, Wang SY, Tien YJ, Tsai PW, Shyur LF.

J Nutr Biochem. 2010 Nov;21(11):1045-59. doi: 10.1016/j.jnutbio.2009.08.010. Epub 2009 Dec 11.

PMID:
20005088
17.

Pharmacokinetics and bioavailability of herbal medicinal products.

Bhattaram VA, Graefe U, Kohlert C, Veit M, Derendorf H.

Phytomedicine. 2002;9 Suppl 3:1-33. Review.

PMID:
12222652
18.

Alkamides from Echinacea inhibit cyclooxygenase-2 activity in human neuroglioma cells.

Hinz B, Woelkart K, Bauer R.

Biochem Biophys Res Commun. 2007 Aug 24;360(2):441-6. Epub 2007 Jun 19.

PMID:
17599805
19.

Cytochrome P450 inhibitory action of Echinacea preparations differs widely and co-varies with alkylamide content.

Modarai M, Gertsch J, Suter A, Heinrich M, Kortenkamp A.

J Pharm Pharmacol. 2007 Apr;59(4):567-73.

PMID:
17430641
20.

Transport of alkamides from Echinacea species through Caco-2 monolayers.

Jager H, Meinel L, Dietz B, Lapke C, Bauer R, Merkle HP, Heilmann J.

Planta Med. 2002 May;68(5):469-71.

PMID:
12058332

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