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Items: 1 to 20 of 148

1.

IKK alpha causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung.

Yang SR, Valvo S, Yao H, Kode A, Rajendrasozhan S, Edirisinghe I, Caito S, Adenuga D, Henry R, Fromm G, Maggirwar S, Li JD, Bulger M, Rahman I.

Am J Respir Cell Mol Biol. 2008 Jun;38(6):689-98. doi: 10.1165/rcmb.2007-0379OC. Epub 2008 Jan 31.

2.

Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genes.

Sundar IK, Chung S, Hwang JW, Lapek JD Jr, Bulger M, Friedman AE, Yao H, Davie JR, Rahman I.

PLoS One. 2012;7(2):e31378. doi: 10.1371/journal.pone.0031378. Epub 2012 Feb 1.

3.

Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling.

Rajendrasozhan S, Chung S, Sundar IK, Yao H, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2010 Feb;298(2):L197-209. doi: 10.1152/ajplung.00265.2009. Epub 2009 Dec 4.

4.

Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications.

Yao H, Hwang JW, Moscat J, Diaz-Meco MT, Leitges M, Kishore N, Li X, Rahman I.

J Biol Chem. 2010 Feb 19;285(8):5405-16. doi: 10.1074/jbc.M109.041418. Epub 2009 Dec 11.

5.

Glutaredoxin 1 regulates cigarette smoke-mediated lung inflammation through differential modulation of I{kappa}B kinases in mice: impact on histone acetylation.

Chung S, Sundar IK, Yao H, Ho YS, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2010 Aug;299(2):L192-203. doi: 10.1152/ajplung.00426.2009. Epub 2010 May 14.

6.

RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke.

Yang SR, Yao H, Rajendrasozhan S, Chung S, Edirisinghe I, Valvo S, Fromm G, McCabe MJ Jr, Sime PJ, Phipps RP, Li JD, Bulger M, Rahman I.

Am J Respir Cell Mol Biol. 2009 Feb;40(2):147-58. doi: 10.1165/rcmb.2008-0207OC. Epub 2008 Aug 7.

7.

NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs.

Chung S, Sundar IK, Hwang JW, Yull FE, Blackwell TS, Kinnula VL, Bulger M, Yao H, Rahman I.

PLoS One. 2011;6(8):e23488. doi: 10.1371/journal.pone.0023488. Epub 2011 Aug 24.

8.

Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging.

Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2007 Feb;292(2):L567-76. Epub 2006 Oct 13.

PMID:
17041012
9.

IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300.

Hoberg JE, Popko AE, Ramsey CS, Mayo MW.

Mol Cell Biol. 2006 Jan;26(2):457-71.

10.

Cigarette smoke induced airway inflammation is independent of NF-κB signalling.

Rastrick JM, Stevenson CS, Eltom S, Grace M, Davies M, Kilty I, Evans SM, Pasparakis M, Catley MC, Lawrence T, Adcock IM, Belvisi MG, Birrell MA.

PLoS One. 2013;8(1):e54128. doi: 10.1371/journal.pone.0054128. Epub 2013 Jan 22. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/754d7b19-2dac-479b-a23c-db9fed0431be.

11.

Activating transcription factor 3 represses cigarette smoke-induced IL6 and IL8 expression via suppressing NF-κB activation.

Wu YP, Cao C, Wu YF, Li M, Lai TW, Zhu C, Wang Y, Ying SM, Chen ZH, Shen HH, Li W.

Toxicol Lett. 2017 Mar 15;270:17-24. doi: 10.1016/j.toxlet.2017.02.002. Epub 2017 Feb 6.

PMID:
28185985
12.

Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages.

Yang SR, Chida AS, Bauter MR, Shafiq N, Seweryniak K, Maggirwar SB, Kilty I, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2006 Jul;291(1):L46-57. Epub 2006 Feb 10.

PMID:
16473865
13.

In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions.

Miao F, Gonzalo IG, Lanting L, Natarajan R.

J Biol Chem. 2004 Apr 23;279(17):18091-7. Epub 2004 Feb 19.

14.

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression.

Anest V, Hanson JL, Cogswell PC, Steinbrecher KA, Strahl BD, Baldwin AS.

Nature. 2003 Jun 5;423(6940):659-63.

PMID:
12789343
15.
17.

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression.

Yamamoto Y, Verma UN, Prajapati S, Kwak YT, Gaynor RB.

Nature. 2003 Jun 5;423(6940):655-9.

PMID:
12789342
18.

New molecular bridge between RelA/p65 and NF-κB target genes via histone acetyltransferase TIP60 cofactor.

Kim JW, Jang SM, Kim CH, An JH, Kang EJ, Choi KH.

J Biol Chem. 2012 Mar 2;287(10):7780-91. doi: 10.1074/jbc.M111.278465. Epub 2012 Jan 16.

19.

Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs.

Marwick JA, Kirkham PA, Stevenson CS, Danahay H, Giddings J, Butler K, Donaldson K, Macnee W, Rahman I.

Am J Respir Cell Mol Biol. 2004 Dec;31(6):633-42. Epub 2004 Aug 27.

PMID:
15333327
20.

Berberine attenuates cigarette smoke-induced acute lung inflammation.

Lin K, Liu S, Shen Y, Li Q.

Inflammation. 2013 Oct;36(5):1079-86. doi: 10.1007/s10753-013-9640-0.

PMID:
23605560

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