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Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation.

Gurel Z, Ronni T, Ho S, Kuchar J, Payne KJ, Turk CW, Dovat S.

J Biol Chem. 2008 Mar 28;283(13):8291-300. doi: 10.1074/jbc.M707906200. Epub 2008 Jan 27.


Ikaros, CK2 kinase, and the road to leukemia.

Dovat S, Song C, Payne KJ, Li Z.

Mol Cell Biochem. 2011 Oct;356(1-2):201-7. doi: 10.1007/s11010-011-0964-5. Epub 2011 Jul 13. Review.


Protein phosphatase 1 (PP1) and Casein Kinase II (CK2) regulate Ikaros-mediated repression of TdT in thymocytes and T-cell leukemia.

Wang H, Song C, Gurel Z, Song N, Ma J, Ouyang H, Lai L, Payne KJ, Dovat S.

Pediatr Blood Cancer. 2014 Dec;61(12):2230-5. doi: 10.1002/pbc.25221. Epub 2014 Sep 11.


Ikaros stability and pericentromeric localization are regulated by protein phosphatase 1.

Popescu M, Gurel Z, Ronni T, Song C, Hung KY, Payne KJ, Dovat S.

J Biol Chem. 2009 May 15;284(20):13869-80. doi: 10.1074/jbc.M900209200. Epub 2009 Mar 11.


Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms.

Ronni T, Payne KJ, Ho S, Bradley MN, Dorsam G, Dovat S.

J Biol Chem. 2007 Jan 26;282(4):2538-47. Epub 2006 Nov 29.


Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator.

Trinh LA, Ferrini R, Cobb BS, Weinmann AS, Hahm K, Ernst P, Garraway IP, Merkenschlager M, Smale ST.

Genes Dev. 2001 Jul 15;15(14):1817-32.


Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.

Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST.

Genes Dev. 2000 Sep 1;14(17):2146-60.


Protein signaling and regulation of gene transcription in leukemia: role of the Casein Kinase II-Ikaros axis.

Gowda CS, Song C, Ding Y, Kapadia M, Dovat S.

J Investig Med. 2016 Mar;64(3):735-9. doi: 10.1136/jim-2016-000075. Epub 2016 Feb 9. Review.


Cell cycle-specific function of Ikaros in human leukemia.

Li Z, Song C, Ouyang H, Lai L, Payne KJ, Dovat S.

Pediatr Blood Cancer. 2012 Jul 15;59(1):69-76. doi: 10.1002/pbc.23406. Epub 2011 Nov 21.


Regulation of Ikaros function by casein kinase 2 and protein phosphatase 1.

Song C, Li Z, Erbe AK, Savic A, Dovat S.

World J Biol Chem. 2011 Jun 26;2(6):126-31. doi: 10.4331/wjbc.v2.i6.126.


Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia.

Wang H, Song C, Ding Y, Pan X, Ge Z, Tan BH, Gowda C, Sachdev M, Muthusami S, Ouyang H, Lai L, Francis OL, Morris CL, Abdel-Azim H, Dorsam G, Xiang M, Payne KJ, Dovat S.

J Biol Chem. 2016 Feb 19;291(8):4004-18. doi: 10.1074/jbc.M115.679332. Epub 2015 Dec 10.


Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes.

Sridharan R, Smale ST.

J Biol Chem. 2007 Oct 12;282(41):30227-38. Epub 2007 Aug 6.


Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin.

Hahm K, Cobb BS, McCarty AS, Brown KE, Klug CA, Lee R, Akashi K, Weissman IL, Fisher AG, Smale ST.

Genes Dev. 1998 Mar 15;12(6):782-96.


The leukemogenic CALM/AF10 fusion protein alters the subcellular localization of the lymphoid regulator Ikaros.

Greif PA, Tizazu B, Krause A, Kremmer E, Bohlander SK.

Oncogene. 2008 May 1;27(20):2886-96. Epub 2007 Nov 26.


Critical function of Ikaros in controlling Aiolos gene expression.

Ghadiri A, Duhamel M, Fleischer A, Reimann A, Dessauge F, Rebollo A.

FEBS Lett. 2007 Apr 17;581(8):1605-16. Epub 2007 Mar 20. Erratum in: FEBS Lett. 2009 May 6;583(9):1554.


Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1.

Chang CW, Chou HY, Lin YS, Huang KH, Chang CJ, Hsu TC, Lee SC.

BMC Mol Biol. 2008 Jul 1;9:61. doi: 10.1186/1471-2199-9-61.


Site-Specific Phosphorylation of Ikaros Induced by Low-Dose Ionizing Radiation Regulates Cell Cycle Progression of B Lymphoblast Through CK2 and AKT Activation.

Cho SJ, Kang H, Kim MY, Lee JE, Kim SJ, Nam SY, Kim JY, Kim HS, Pyo S, Yang KH.

Int J Radiat Oncol Biol Phys. 2016 Apr 1;94(5):1207-18. doi: 10.1016/j.ijrobp.2016.01.008. Epub 2016 Jan 14.


Phosphorylation site mutations in heterochromatin protein 1 (HP1) reduce or eliminate silencing activity.

Zhao T, Heyduk T, Eissenberg JC.

J Biol Chem. 2001 Mar 23;276(12):9512-8. Epub 2000 Dec 19.


Ikaros negatively regulates inducible nitric oxide synthase expression in macrophages: involvement of Ikaros phosphorylation by casein kinase 2.

Cho SJ, Huh JE, Song J, Rhee DK, Pyo S.

Cell Mol Life Sci. 2008 Oct;65(20):3290-303. doi: 10.1007/s00018-008-8332-7.


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