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cDNA microarray and bioinformatic analysis of nuclear factor-kappaB related genes in squamous cell carcinoma.

Chen Z, Lee TL, Yang XP, Dong G, Loercher A, Van Waes C.

Methods Mol Biol. 2007;383:81-99.


Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma.

Loercher A, Lee TL, Ricker JL, Howard A, Geoghegen J, Chen Z, Sunwoo JB, Sitcheran R, Chuang EY, Mitchell JB, Baldwin AS Jr, Van Waes C.

Cancer Res. 2004 Sep 15;64(18):6511-23. Erratum in: Cancer Res. 2004 Nov 1;64(21):8130-2.


Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-kappaB signaling as characteristics of a high-risk head and neck squamous cell carcinoma.

Chung CH, Parker JS, Ely K, Carter J, Yi Y, Murphy BA, Ang KK, El-Naggar AK, Zanation AM, Cmelak AJ, Levy S, Slebos RJ, Yarbrough WG.

Cancer Res. 2006 Aug 15;66(16):8210-8.


Nuclear factor-kappaB signature of inflammatory breast cancer by cDNA microarray validated by quantitative real-time reverse transcription-PCR, immunohistochemistry, and nuclear factor-kappaB DNA-binding.

Van Laere SJ, Van der Auwera I, Van den Eynden GG, Elst HJ, Weyler J, Harris AL, van Dam P, Van Marck EA, Vermeulen PB, Dirix LY.

Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3249-56.


Role of activated nuclear factor-kappaB in the pathogenesis and therapy of squamous cell carcinoma of the head and neck.

Allen CT, Ricker JL, Chen Z, Van Waes C.

Head Neck. 2007 Oct;29(10):959-71. Review.


A novel nuclear factor-kappaB gene signature is differentially expressed in head and neck squamous cell carcinomas in association with TP53 status.

Lee TL, Yang XP, Yan B, Friedman J, Duggal P, Bagain L, Dong G, Yeh NT, Wang J, Zhou J, Elkahloun A, Van Waes C, Chen Z.

Clin Cancer Res. 2007 Oct 1;13(19):5680-91.


Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells.

Ortis F, Pirot P, Naamane N, Kreins AY, Rasschaert J, Moore F, Théâtre E, Verhaeghe C, Magnusson NE, Chariot A, Orntoft TF, Eizirik DL.

Diabetologia. 2008 Jul;51(7):1213-25. doi: 10.1007/s00125-008-0999-7.


NF-kappaB gene signatures and p53 mutations in head and neck squamous cell carcinoma.

Ferris RL, Grandis JR.

Clin Cancer Res. 2007 Oct 1;13(19):5663-4. Review. No abstract available.


Genome-wide analysis of gene expression in T cells to identify targets of the NF-kappa B transcription factor c-Rel.

Bunting K, Rao S, Hardy K, Woltring D, Denyer GS, Wang J, Gerondakis S, Shannon MF.

J Immunol. 2007 Jun 1;178(11):7097-109.


Elevated expression of genes assigned to NF-kappaB and apoptotic pathways in human periodontal ligament fibroblasts following mechanical stretch.

Ritter N, Mussig E, Steinberg T, Kohl A, Komposch G, Tomakidi P.

Cell Tissue Res. 2007 Jun;328(3):537-48.


Gene expression profiling of human alveolar macrophages infected by B. anthracis spores demonstrates TNF-alpha and NF-kappab are key components of the innate immune response to the pathogen.

Dozmorov M, Wu W, Chakrabarty K, Booth JL, Hurst RE, Coggeshall KM, Metcalf JP.

BMC Infect Dis. 2009 Sep 10;9:152. doi: 10.1186/1471-2334-9-152.


Antibody-based proteomics for esophageal cancer: Identification of proteins in the nuclear factor-kappaB pathway and mitotic checkpoint.

Uemura N, Nakanishi Y, Kato H, Nagino M, Hirohashi S, Kondo T.

Cancer Sci. 2009 Sep;100(9):1612-22. doi: 10.1111/j.1349-7006.2009.01230.x.


NF-Kappa-B downregulation strategies in head and neck cancer treatment.

Patel A, Miller L, Ahmed K, Ondrey F.

Otolaryngol Head Neck Surg. 2004 Sep;131(3):288-95.


The LIM-homeodomain transcription factor LMX1B regulates expression of NF-kappa B target genes.

Rascle A, Neumann T, Raschta AS, Neumann A, Heining E, Kastner J, Witzgall R.

Exp Cell Res. 2009 Jan 1;315(1):76-96. doi: 10.1016/j.yexcr.2008.10.012.


The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma.

Sugimoto T, Seki N, Shimizu S, Kikkawa N, Tsukada J, Shimada H, Sasaki K, Hanazawa T, Okamoto Y, Hata A.

Genes Chromosomes Cancer. 2009 Feb;48(2):132-42. doi: 10.1002/gcc.20626.


A systems biology approach to identify the combination effects of human herpesvirus 8 genes on NF-kappaB activation.

Konrad A, Wies E, Thurau M, Marquardt G, Naschberger E, Hentschel S, Jochmann R, Schulz TF, Erfle H, Brors B, Lausen B, Neipel F, Stürzl M.

J Virol. 2009 Mar;83(6):2563-74. doi: 10.1128/JVI.01512-08.

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