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Items: 1 to 20 of 85

1.

A tale of two Paks.

Arias-Romero LE, Chernoff J.

Biol Cell. 2008 Feb;100(2):97-108. doi: 10.1042/BC20070109. Review.

PMID:
18199048
2.

PAK signaling in oncogenesis.

Molli PR, Li DQ, Murray BW, Rayala SK, Kumar R.

Oncogene. 2009 Jul 16;28(28):2545-55. doi: 10.1038/onc.2009.119. Epub 2009 May 25. Review.

3.

P21 activated kinases: structure, regulation, and functions.

Rane CK, Minden A.

Small GTPases. 2014;5. pii: e28003. doi: 10.4161/sgtp.28003. Epub 2014 Mar 21. Review.

4.

Role of p-21-activated kinases in cancer progression.

King H, Nicholas NS, Wells CM.

Int Rev Cell Mol Biol. 2014;309:347-87. doi: 10.1016/B978-0-12-800255-1.00007-7. Review.

PMID:
24529727
5.

Involvement of Rac/Cdc42/PAK pathway in cytoskeletal rearrangements.

Szczepanowska J.

Acta Biochim Pol. 2009;56(2):225-34. Epub 2009 Jun 10. Review.

6.

Pak protein kinases and their role in cancer.

Dummler B, Ohshiro K, Kumar R, Field J.

Cancer Metastasis Rev. 2009 Jun;28(1-2):51-63. doi: 10.1007/s10555-008-9168-1. Review.

7.

Signaling, Regulation, and Specificity of the Type II p21-activated Kinases.

Ha BH, Morse EM, Turk BE, Boggon TJ.

J Biol Chem. 2015 May 22;290(21):12975-83. doi: 10.1074/jbc.R115.650416. Epub 2015 Apr 8. Review.

8.

UnPAKing the class differences among p21-activated kinases.

Eswaran J, Soundararajan M, Kumar R, Knapp S.

Trends Biochem Sci. 2008 Aug;33(8):394-403. doi: 10.1016/j.tibs.2008.06.002. Epub 2008 Jul 17. Review.

PMID:
18639460
9.

Group I p21-activated kinases (PAKs) promote tumor cell proliferation and survival through the AKT1 and Raf-MAPK pathways.

Menges CW, Sementino E, Talarchek J, Xu J, Chernoff J, Peterson JR, Testa JR.

Mol Cancer Res. 2012 Sep;10(9):1178-88. Epub 2012 Jul 12.

10.

Structure, biochemistry, and biology of PAK kinases.

Kumar R, Sanawar R, Li X, Li F.

Gene. 2017 Mar 20;605:20-31. doi: 10.1016/j.gene.2016.12.014. Epub 2016 Dec 19. Review.

PMID:
28007610
11.

p21-activated kinases and gastrointestinal cancer.

He H, Baldwin GS.

Biochim Biophys Acta. 2013 Jan;1833(1):33-9. doi: 10.1016/j.bbamcr.2012.10.015. Epub 2012 Oct 22. Review.

12.

p21-activated kinases: three more join the Pak.

Jaffer ZM, Chernoff J.

Int J Biochem Cell Biol. 2002 Jul;34(7):713-7. Review.

PMID:
11950587
13.

Biology of the p21-activated kinases.

Bokoch GM.

Annu Rev Biochem. 2003;72:743-81. Epub 2003 Mar 27. Review.

PMID:
12676796
14.

p21-Activated kinase 5: a pleiotropic kinase.

Wen YY, Wang XX, Pei DS, Zheng JN.

Bioorg Med Chem Lett. 2013 Dec 15;23(24):6636-9. doi: 10.1016/j.bmcl.2013.10.051. Epub 2013 Oct 31. Review.

PMID:
24215894
15.

p21-Activated kinase inhibitors: a patent review.

Crawford JJ, Hoeflich KP, Rudolph J.

Expert Opin Ther Pat. 2012 Mar;22(3):293-310. doi: 10.1517/13543776.2012.668758. Epub 2012 Mar 11. Review.

PMID:
22404134
16.

Group I p21-activated kinases: emerging roles in immune function and viral pathogenesis.

Pacheco A, Chernoff J.

Int J Biochem Cell Biol. 2010 Jan;42(1):13-6. doi: 10.1016/j.biocel.2009.09.006. Epub 2009 Sep 9. Review.

17.

PAK thread from amoeba to mammals.

Kumar A, Molli PR, Pakala SB, Bui Nguyen TM, Rayala SK, Kumar R.

J Cell Biochem. 2009 Jul 1;107(4):579-85. doi: 10.1002/jcb.22159. Review.

18.

The emerging importance of group II PAKs.

Wells CM, Jones GE.

Biochem J. 2010 Jan 15;425(3):465-73. doi: 10.1042/BJ20091173. Review.

PMID:
20070256
19.

Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway.

Déléris P, Trost M, Topisirovic I, Tanguay PL, Borden KL, Thibault P, Meloche S.

J Biol Chem. 2011 Feb 25;286(8):6470-8. doi: 10.1074/jbc.M110.181529. Epub 2010 Dec 22.

20.

An oncogenic kinase: putting PAK5 forward.

Wen YY, Zheng JN, Pei DS.

Expert Opin Ther Targets. 2014 Jul;18(7):807-15. doi: 10.1517/14728222.2014.918103. Epub 2014 May 29. Review.

PMID:
24869804

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