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Items: 1 to 20 of 1086

1.

Tumor suppressor LATS1 is a negative regulator of oncogene YAP.

Hao Y, Chun A, Cheung K, Rashidi B, Yang X.

J Biol Chem. 2008 Feb 29;283(9):5496-509. Epub 2007 Dec 24.

2.

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.

Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, Zheng P, Ye K, Chinnaiyan A, Halder G, Lai ZC, Guan KL.

Genes Dev. 2007 Nov 1;21(21):2747-61.

3.

Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein.

Zhao B, Kim J, Ye X, Lai ZC, Guan KL.

Cancer Res. 2009 Feb 1;69(3):1089-98. doi: 10.1158/0008-5472.CAN-08-2997. Epub 2009 Jan 13.

4.

Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway.

Zhang J, Smolen GA, Haber DA.

Cancer Res. 2008 Apr 15;68(8):2789-94. doi: 10.1158/0008-5472.CAN-07-6205.

5.

Mammalian NDR/LATS protein kinases in hippo tumor suppressor signaling.

Hergovich A, Hemmings BA.

Biofactors. 2009 Jul-Aug;35(4):338-45. doi: 10.1002/biof.47. Review.

PMID:
19484742
6.

Transcriptional output of the Salvador/warts/hippo pathway is controlled in distinct fashions in Drosophila melanogaster and mammalian cell lines.

Zhang X, Milton CC, Humbert PO, Harvey KF.

Cancer Res. 2009 Aug 1;69(15):6033-41. doi: 10.1158/0008-5472.CAN-08-4592. Epub 2009 Jul 7.

7.

TEAD mediates YAP-dependent gene induction and growth control.

Zhao B, Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY, Chinnaiyan AM, Lai ZC, Guan KL.

Genes Dev. 2008 Jul 15;22(14):1962-71. doi: 10.1101/gad.1664408. Epub 2008 Jun 25.

8.

LATS1 tumor suppressor regulates G2/M transition and apoptosis.

Xia H, Qi H, Li Y, Pei J, Barton J, Blackstad M, Xu T, Tao W.

Oncogene. 2002 Feb 14;21(8):1233-41.

9.
10.

The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1.

Chan EH, Nousiainen M, Chalamalasetty RB, Schäfer A, Nigg EA, Silljé HH.

Oncogene. 2005 Mar 17;24(12):2076-86.

PMID:
15688006
11.

The bantam microRNA is a target of the hippo tumor-suppressor pathway.

Nolo R, Morrison CM, Tao C, Zhang X, Halder G.

Curr Biol. 2006 Oct 10;16(19):1895-904. Epub 2006 Aug 31.

12.

Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila.

Wei X, Shimizu T, Lai ZC.

EMBO J. 2007 Apr 4;26(7):1772-81. Epub 2007 Mar 8.

13.

Metabolic control of YAP and TAZ by the mevalonate pathway.

Sorrentino G, Ruggeri N, Specchia V, Cordenonsi M, Mano M, Dupont S, Manfrin A, Ingallina E, Sommaggio R, Piazza S, Rosato A, Piccolo S, Del Sal G.

Nat Cell Biol. 2014 Apr;16(4):357-66. doi: 10.1038/ncb2936. Epub 2014 Mar 23.

PMID:
24658687
14.

RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3.

Jang JW, Kim MK, Lee YS, Lee JW, Kim DM, Song SH, Lee JY, Choi BY, Min B, Chi XZ, Bae SC.

Oncogene. 2017 Feb 16;36(7):999-1011. doi: 10.1038/onc.2016.266. Epub 2016 Jul 18.

PMID:
27425596
15.

Identification of LATS transcriptional targets in HeLa cells using whole human genome oligonucleotide microarray.

Visser S, Yang X.

Gene. 2010 Jan 1;449(1-2):22-9. doi: 10.1016/j.gene.2009.09.008. Epub 2009 Sep 30.

PMID:
19799973
16.

Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP).

Oka T, Mazack V, Sudol M.

J Biol Chem. 2008 Oct 10;283(41):27534-46. doi: 10.1074/jbc.M804380200. Epub 2008 Jul 17.

17.

Intestinal regeneration: YAP-tumor suppressor and oncoprotein?

Li VS, Clevers H.

Curr Biol. 2013 Feb 4;23(3):R110-2. doi: 10.1016/j.cub.2012.12.021.

18.

SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila.

Goulev Y, Fauny JD, Gonzalez-Marti B, Flagiello D, Silber J, Zider A.

Curr Biol. 2008 Mar 25;18(6):435-41. doi: 10.1016/j.cub.2008.02.034. Epub 2008 Feb 28.

19.

Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity.

Tao W, Zhang S, Turenchalk GS, Stewart RA, St John MA, Chen W, Xu T.

Nat Genet. 1999 Feb;21(2):177-81.

PMID:
9988268
20.

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