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Effective induction of anti-tumor immune responses with oligomannose-coated liposome targeting to intraperitoneal phagocytic cells.

Ikehara Y, Shiuchi N, Kabata-Ikehara S, Nakanishi H, Yokoyama N, Takagi H, Nagata T, Koide Y, Kuzushima K, Takahashi T, Tsujimura K, Kojima N.

Cancer Lett. 2008 Feb 18;260(1-2):137-45.


Oligomannose-coated liposomes as a therapeutic antigen-delivery and an adjuvant vehicle for induction of in vivo tumor immunity.

Kojima N, Biao L, Nakayama T, Ishii M, Ikehara Y, Tsujimura K.

J Control Release. 2008 Jul 2;129(1):26-32. doi: 10.1016/j.jconrel.2008.03.023. Epub 2008 Apr 7.


An essential role of antigen-presenting cell/T-helper type 1 cell-cell interactions in draining lymph node during complete eradication of class II-negative tumor tissue by T-helper type 1 cell therapy.

Chamoto K, Wakita D, Narita Y, Zhang Y, Noguchi D, Ohnishi H, Iguchi T, Sakai T, Ikeda H, Nishimura T.

Cancer Res. 2006 Feb 1;66(3):1809-17.


Primary T-cell and activated macrophage response associated with tumor protection using peptide/poly-N-acetyl glucosamine vaccination.

Maitre N, Brown JM, Demcheva M, Kelley JR, Lockett MA, Vournakis J, Cole DJ.

Clin Cancer Res. 1999 May;5(5):1173-82.


Augmented induction of CD8+ cytotoxic T-cell response and antitumour resistance by T helper type 1-inducing peptide.

Kikuchi T, Uehara S, Ariga H, Tokunaga T, Kariyone A, Tamura T, Takatsu K.

Immunology. 2006 Jan;117(1):47-58.


Targeted delivery of oligomannose-coated liposome to the omental micrometastasis by peritoneal macrophages from patients with gastric cancer.

Matsui M, Shimizu Y, Kodera Y, Kondo E, Ikehara Y, Nakanishi H.

Cancer Sci. 2010 Jul;101(7):1670-7. doi: 10.1111/j.1349-7006.2010.01587.x. Epub 2010 Apr 7.


Tetramer-blocking assay for defining antigen-specific cytotoxic T lymphocytes using peptide-MHC tetramer.

Yokouchi H, Chamoto K, Wakita D, Noguchi D, Yamazaki K, Dosaka-Akita H, Nishimura M, Ikeda H, Nishimura T.

Cancer Sci. 2006 Feb;97(2):148-54.


Deoxyribonucleic acid (DNA) encoding a pan-major histocompatibility complex class II peptide analogue augmented antigen-specific cellular immunity and suppressive effects on tumor growth elicited by DNA vaccine immunotherapy.

Teramoto K, Kontani K, Ozaki Y, Sawai S, Tezuka N, Nagata T, Fujino S, Itoh Y, Taguchi O, Koide Y, Asai T, Ohkubo I, Ogasawara K.

Cancer Res. 2003 Nov 15;63(22):7920-5.


Immunization with a lentiviral vector stimulates both CD4 and CD8 T cell responses to an ovalbumin transgene.

Rowe HM, Lopes L, Ikeda Y, Bailey R, Barde I, Zenke M, Chain BM, Collins MK.

Mol Ther. 2006 Feb;13(2):310-9. Epub 2005 Nov 4.


Active CD4+ helper T cells directly stimulate CD8+ cytotoxic T lymphocyte responses in wild-type and MHC II gene knockout C57BL/6 mice and transgenic RIP-mOVA mice expressing islet beta-cell ovalbumin antigen leading to diabetes.

Ye Z, Ahmed KA, Hao S, Zhang X, Xie Y, Munegowda MA, Meng Q, Chibbar R, Xiang J.

Autoimmunity. 2008 Nov;41(7):501-11. doi: 10.1080/08916930802069256.


Reversal of CD8+ T cell ignorance and induction of anti-tumor immunity by peptide-pulsed APC.

Dalyot-Herman N, Bathe OF, Malek TR.

J Immunol. 2000 Dec 15;165(12):6731-7.


Delivery of protein antigens to the immune system by fusion-active virosomes: a comparison with liposomes and ISCOMs.

Bungener L, Huckriede A, Wilschut J, Daemen T.

Biosci Rep. 2002 Apr;22(2):323-38. Review.


Phagocyte-induced antigen-specific activation of unprimed CD8+ T cells in vitro.

De Bruijn ML, Jackson MR, Peterson PA.

Eur J Immunol. 1995 May;25(5):1274-85.


Cross-priming of T cell responses by synthetic microspheres carrying a CD8+ T cell epitope requires an adjuvant signal.

Boisgérault F, Rueda P, Sun CM, Hervas-Stubbs S, Rojas M, Leclerc C.

J Immunol. 2005 Mar 15;174(6):3432-9.


Linked foreign T-cell help activates self-reactive CTL and inhibits tumor growth.

Steinaa L, Rasmussen PB, Wegener AM, Sonderbye L, Leach DR, Rygaard J, Mouritsen S, Gautam AM.

J Immunol. 2005 Jul 1;175(1):329-34.

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