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Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor.

Memarzadeh S, Xin L, Mulholland DJ, Mansukhani A, Wu H, Teitell MA, Witte ON.

Cancer Cell. 2007 Dec;12(6):572-85.


Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal.

Memarzadeh S, Cai H, Janzen DM, Xin L, Lukacs R, Riedinger M, Zong Y, DeGendt K, Verhoeven G, Huang J, Witte ON.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7962-7. doi: 10.1073/pnas.1105243108. Epub 2011 Apr 25.


2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits fibroblast growth factor 10-induced prostatic bud formation in mouse urogenital sinus.

Vezina CM, Hardin HA, Moore RW, Allgeier SH, Peterson RE.

Toxicol Sci. 2010 Jan;113(1):198-206. doi: 10.1093/toxsci/kfp226. Epub 2009 Oct 4.


Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate.

Jin C, McKeehan K, Guo W, Jauma S, Ittmann MM, Foster B, Greenberg NM, McKeehan WL, Wang F.

Cancer Res. 2003 Dec 15;63(24):8784-90.


Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors.

Volckaert T, Campbell A, Dill E, Li C, Minoo P, De Langhe S.

Development. 2013 Sep;140(18):3731-42. doi: 10.1242/dev.096560. Epub 2013 Aug 7.


Initiation of prostate cancer in mice by Tp53R270H: evidence for an alternative molecular progression.

Vinall RL, Chen JQ, Hubbard NE, Sulaimon SS, Shen MM, Devere White RW, Borowsky AD.

Dis Model Mech. 2012 Nov;5(6):914-20. doi: 10.1242/dmm.008995. Epub 2012 Apr 12.


Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition.

Acevedo VD, Gangula RD, Freeman KW, Li R, Zhang Y, Wang F, Ayala GE, Peterson LE, Ittmann M, Spencer DM.

Cancer Cell. 2007 Dec;12(6):559-71.


Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice.

Elo TD, Valve EM, Seppänen JA, Vuorikoski HJ, Mäkelä SI, Poutanen M, Kujala PM, Härkönen PL.

Neoplasia. 2010 Nov;12(11):915-27.


Prostatic growth and development are regulated by FGF10.

Thomson AA, Cunha GR.

Development. 1999 Aug;126(16):3693-701.


Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a.

Chung D, Gao F, Jegga AG, Das SK.

Mol Cell Endocrinol. 2015 Jan 15;400:48-60. doi: 10.1016/j.mce.2014.11.002. Epub 2014 Nov 7.


ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells.

Zong Y, Xin L, Goldstein AS, Lawson DA, Teitell MA, Witte ON.

Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12465-70. doi: 10.1073/pnas.0905931106. Epub 2009 Jul 10.


Conditional expression of the androgen receptor induces oncogenic transformation of the mouse prostate.

Zhu C, Luong R, Zhuo M, Johnson DT, McKenney JK, Cunha GR, Sun Z.

J Biol Chem. 2011 Sep 23;286(38):33478-88. doi: 10.1074/jbc.M111.269894. Epub 2011 Jul 27.


Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.

Volckaert T, Dill E, Campbell A, Tiozzo C, Majka S, Bellusci S, De Langhe SP.

J Clin Invest. 2011 Nov;121(11):4409-19. doi: 10.1172/JCI58097. Epub 2011 Oct 10.


Identification of a cell of origin for human prostate cancer.

Goldstein AS, Huang J, Guo C, Garraway IP, Witte ON.

Science. 2010 Jul 30;329(5991):568-71. doi: 10.1126/science.1189992.


Fibroblast growth factor signaling regulates the expansion of A6-expressing hepatocytes in association with AKT-dependent β-catenin activation.

Utley S, James D, Mavila N, Nguyen MV, Vendryes C, Salisbury SM, Phan J, Wang KS.

J Hepatol. 2014 May;60(5):1002-9. doi: 10.1016/j.jhep.2013.12.017. Epub 2013 Dec 21.


Characterizing the contribution of stem/progenitor cells to tumorigenesis in the Pten-/-TP53-/- prostate cancer model.

Abou-Kheir WG, Hynes PG, Martin PL, Pierce R, Kelly K.

Stem Cells. 2010 Dec;28(12):2129-40. doi: 10.1002/stem.538.


Transforming growth factor beta 1 and androgen receptors in prostate neoplasia.

Cardillo MR, Petrangeli E, Salvatori L, Ravenna L, Di Silverio F.

Anal Quant Cytol Histol. 2000 Oct;22(5):403-10.


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