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Items: 1 to 20 of 114

1.

Force-induced bidirectional stepping of cytoplasmic dynein.

Gennerich A, Carter AP, Reck-Peterson SL, Vale RD.

Cell. 2007 Nov 30;131(5):952-65.

2.

Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains.

Nicholas MP, Berger F, Rao L, Brenner S, Cho C, Gennerich A.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):6371-6. doi: 10.1073/pnas.1417422112. Epub 2015 May 4.

3.

Single-molecule analysis of dynein processivity and stepping behavior.

Reck-Peterson SL, Yildiz A, Carter AP, Gennerich A, Zhang N, Vale RD.

Cell. 2006 Jul 28;126(2):335-48.

4.

A simple theoretical model explains dynein's response to load.

Gao YQ.

Biophys J. 2006 Feb 1;90(3):811-21. Epub 2005 Nov 11.

5.

Cytoplasmic dynein moves through uncoordinated stepping of the AAA+ ring domains.

DeWitt MA, Chang AY, Combs PA, Yildiz A.

Science. 2012 Jan 13;335(6065):221-5. doi: 10.1126/science.1215804. Epub 2011 Dec 8.

6.

Molecular motors: Dynein's gearbox.

Cross RA.

Curr Biol. 2004 May 4;14(9):R355-6. Review.

7.

Two independent switches regulate cytoplasmic dynein's processivity and directionality.

Walter WJ, Koonce MP, Brenner B, Steffen W.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5289-93. doi: 10.1073/pnas.1116315109. Epub 2012 Mar 12.

8.

Reconstitution of dynein transport to the microtubule plus end by kinesin.

Roberts AJ, Goodman BS, Reck-Peterson SL.

Elife. 2014 Jun 10;3:e02641. doi: 10.7554/eLife.02641.

10.

Cytoplasmic dynein functions as a gear in response to load.

Mallik R, Carter BC, Lex SA, King SJ, Gross SP.

Nature. 2004 Feb 12;427(6975):649-52.

PMID:
14961123
11.

Tension on the linker gates the ATP-dependent release of dynein from microtubules.

Cleary FB, Dewitt MA, Bilyard T, Htet ZM, Belyy V, Chan DD, Chang AY, Yildiz A.

Nat Commun. 2014 Aug 11;5:4587. doi: 10.1038/ncomms5587.

12.

Model for bidirectional movement of cytoplasmic dynein.

Sumathy S, Satyanarayana SV.

J Theor Biol. 2015 Sep 7;380:48-52. doi: 10.1016/j.jtbi.2015.04.029. Epub 2015 May 2.

PMID:
25944174
13.

Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor.

Huang J, Roberts AJ, Leschziner AE, Reck-Peterson SL.

Cell. 2012 Aug 31;150(5):975-86. doi: 10.1016/j.cell.2012.07.022.

14.

Dynein arms are strain-dependent direction-switching force generators.

Shingyoji C, Nakano I, Inoue Y, Higuchi H.

Cytoskeleton (Hoboken). 2015 Aug;72(8):388-401. doi: 10.1002/cm.21232. Epub 2015 Aug 31.

PMID:
26242795
15.

Multiscale approaches for studying energy transduction in dynein.

Serohijos AW, Tsygankov D, Liu S, Elston TC, Dokholyan NV.

Phys Chem Chem Phys. 2009 Jun 28;11(24):4840-50. doi: 10.1039/b902028d. Epub 2009 May 15. Review.

16.

Three-dimensional structure of cytoplasmic dynein bound to microtubules.

Mizuno N, Narita A, Kon T, Sutoh K, Kikkawa M.

Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20832-7. Epub 2007 Dec 19.

17.

Distinct functions of nucleotide-binding/hydrolysis sites in the four AAA modules of cytoplasmic dynein.

Kon T, Nishiura M, Ohkura R, Toyoshima YY, Sutoh K.

Biochemistry. 2004 Sep 7;43(35):11266-74.

PMID:
15366936
18.

Structural basis for microtubule binding and release by dynein.

Redwine WB, Hernandez-Lopez R, Zou S, Huang J, Reck-Peterson SL, Leschziner AE.

Science. 2012 Sep 21;337(6101):1532-1536. doi: 10.1126/science.1224151.

19.

A physical model reveals the mechanochemistry responsible for dynein's processive motion.

Tsygankov D, Serohijos AW, Dokholyan NV, Elston TC.

Biophys J. 2011 Jul 6;101(1):144-50. doi: 10.1016/j.bpj.2011.05.043.

20.

Cytoplasmic dynein transports cargos via load-sharing between the heads.

Belyy V, Hendel NL, Chien A, Yildiz A.

Nat Commun. 2014 Nov 26;5:5544. doi: 10.1038/ncomms6544.

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