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Items: 1 to 20 of 70

1.

Dynamic and redundant regulation of LRRK2 and LRRK1 expression.

Biskup S, Moore DJ, Rea A, Lorenz-Deperieux B, Coombes CE, Dawson VL, Dawson TM, West AB.

BMC Neurosci. 2007 Nov 28;8:102.

2.

Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease.

Westerlund M, Belin AC, Anvret A, Bickford P, Olson L, Galter D.

Neuroscience. 2008 Mar 18;152(2):429-36. doi: 10.1016/j.neuroscience.2007.10.062. Epub 2008 Jan 10.

PMID:
18272292
3.

Expression analysis of Lrrk1, Lrrk2 and Lrrk2 splice variants in mice.

Giesert F, Hofmann A, Bürger A, Zerle J, Kloos K, Hafen U, Ernst L, Zhang J, Vogt-Weisenhorn DM, Wurst W.

PLoS One. 2013 May 10;8(5):e63778. doi: 10.1371/journal.pone.0063778. Print 2013.

4.

Phosphorylation of 4E-BP1 in the mammalian brain is not altered by LRRK2 expression or pathogenic mutations.

Trancikova A, Mamais A, Webber PJ, Stafa K, Tsika E, Glauser L, West AB, Bandopadhyay R, Moore DJ.

PLoS One. 2012;7(10):e47784. doi: 10.1371/journal.pone.0047784. Epub 2012 Oct 17.

5.

Human leucine-rich repeat kinase 1 and 2: intersecting or unrelated functions?

Civiero L, Bubacco L.

Biochem Soc Trans. 2012 Oct;40(5):1095-101. Review.

PMID:
22988872
6.

Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents.

West AB, Cowell RM, Daher JP, Moehle MS, Hinkle KM, Melrose HL, Standaert DG, Volpicelli-Daley LA.

J Comp Neurol. 2014 Aug 1;522(11):2465-80. doi: 10.1002/cne.23583. Epub 2014 Apr 12.

7.

Gene and MicroRNA transcriptome analysis of Parkinson's related LRRK2 mouse models.

Dorval V, Mandemakers W, Jolivette F, Coudert L, Mazroui R, De Strooper B, Hébert SS.

PLoS One. 2014 Jan 10;9(1):e85510. doi: 10.1371/journal.pone.0085510. eCollection 2014.

8.

The Parkinson disease gene LRRK2: evolutionary and structural insights.

Marín I.

Mol Biol Evol. 2006 Dec;23(12):2423-33. Epub 2006 Sep 11.

9.

Expression of leucine-rich-repeat-kinase 2 (LRRK2) during embryonic development.

Zechel S, Meinhardt A, Unsicker K, von Bohlen Und Halbach O.

Int J Dev Neurosci. 2010 Aug;28(5):391-9. doi: 10.1016/j.ijdevneu.2010.04.002. Epub 2010 Apr 18.

PMID:
20403420
10.

A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.

Melrose HL, Kent CB, Taylor JP, Dachsel JC, Hinkle KM, Lincoln SJ, Mok SS, Culvenor JG, Masters CL, Tyndall GM, Bass DI, Ahmed Z, Andorfer CA, Ross OA, Wszolek ZK, Delldonne A, Dickson DW, Farrer MJ.

Neuroscience. 2007 Jul 29;147(4):1047-58. Epub 2007 Jul 3.

PMID:
17611037
11.
12.

Leucine-rich repeat kinase 2 modulates retinoic acid-induced neuronal differentiation of murine embryonic stem cells.

Schulz C, Paus M, Frey K, Schmid R, Kohl Z, Mennerich D, Winkler J, Gillardon F.

PLoS One. 2011;6(6):e20820. doi: 10.1371/journal.pone.0020820. Epub 2011 Jun 9.

13.

The mouse/human cross-species heterodimer of leucine-rich repeat kinase 2: possible significance in the transgenic model mouse of Parkinson's disease.

Miyajima T, Ohta E, Kawada H, Maekawa T, Obata F.

Neurosci Lett. 2015 Feb 19;588:142-6. doi: 10.1016/j.neulet.2015.01.003. Epub 2015 Jan 3.

PMID:
25562633
14.

Distribution of PINK1 and LRRK2 in rat and mouse brain.

Taymans JM, Van den Haute C, Baekelandt V.

J Neurochem. 2006 Aug;98(3):951-61. Epub 2006 Jun 12.

15.

Age-dependent and cell-population-restricted LRRK2 expression in normal mouse spleen.

Maekawa T, Kubo M, Yokoyama I, Ohta E, Obata F.

Biochem Biophys Res Commun. 2010 Feb 12;392(3):431-5. doi: 10.1016/j.bbrc.2010.01.041. Epub 2010 Jan 15.

PMID:
20079710
16.

Anatomical localization of leucine-rich repeat kinase 2 in mouse brain.

Melrose H, Lincoln S, Tyndall G, Dickson D, Farrer M.

Neuroscience. 2006;139(3):791-4. Epub 2006 Feb 28.

PMID:
16504409
17.

Ancient origin of the Parkinson disease gene LRRK2.

Marín I.

J Mol Evol. 2008 Jul;67(1):41-50. doi: 10.1007/s00239-008-9122-4. Epub 2008 Jun 4.

PMID:
18523712
18.

Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies.

Davies P, Hinkle KM, Sukar NN, Sepulveda B, Mesias R, Serrano G, Alessi DR, Beach TG, Benson DL, White CL, Cowell RM, Das SS, West AB, Melrose HL.

Biochem J. 2013 Jul 1;453(1):101-13. doi: 10.1042/BJ20121742.

19.

Leucine-rich repeat kinase 1: a paralog of LRRK2 and a candidate gene for Parkinson's disease.

Taylor JP, Hulihan MM, Kachergus JM, Melrose HL, Lincoln SJ, Hinkle KM, Stone JT, Ross OA, Hauser R, Aasly J, Gasser T, Payami H, Wszolek ZK, Farrer MJ.

Neurogenetics. 2007 Apr;8(2):95-102. Epub 2007 Jan 16.

PMID:
17225181
20.

Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment.

Klein CL, Rovelli G, Springer W, Schall C, Gasser T, Kahle PJ.

J Neurochem. 2009 Nov;111(3):703-15. doi: 10.1111/j.1471-4159.2009.06358.x. Epub 2009 Aug 27.

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